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Identification of Novel Natural Inhibitors Of Proteins Involved In Cancer Cell Stemness
(Central University of Punjab, 2018)
Cancer stem cells (CSCs) are a small subpopulation of cells identified in a variety of tumors that are capable of self-renewal, differentiation and have the unique property to evade radiotherapy and chemotherapy. CSCs are ...
Identification of natural inhibitors of proteins involved in the pathology of Parkinson's disease
(Central University of Punjab, 2018)
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused due to the lack of dopamine in the brain. Different drug therapies are available for PD showing excellent efficiency, but most of them are cost ...
Role of Helicobacter pylori Enriched Media in Inducing Oxidative Stress in Human Cell lines
(Central University of Punjab, 2018)
Helicobacter pylori is a gram-negative, helical, microaerophilic bacterium which colonizes the human gastrointestinal tract. Vacuolating cytotoxin A (VacA) is one of the major virulent factors. Reactive oxygen species (ROS) ...
Extraction And Identification Of Secondary Metabolites Produced By Soil Actinomycetes And Their Biochemical Characterization
(Central University of Punjab, 2018)
The worldwide use of antibiotics has rapidly increased since the discovery of penicillin in 1928 by Alexander Fleming, for treating terrible bacterial diseases. But in due course of time, over-consumption of antibiotics ...
Expression, Purification and Kinetic Characterization of Lactate Dehydrogenase of Lactic Acid Bacteria and ProB of Bacillus subtilis
(Central University of Punjab, 2018)
Lactate dehydrogenase is very well known for its role in glucose metabolism in Lactic Acid Bacteria (LAB). These bacteria are widely used in the industrial and research areas. LAB use NADH as a cofactor to produce lactate ...
Role of Plant Growth Promoting Bacteria in Improving the Quality of Marginal Soil for Multiple Purposes
(Central University of Punjab, 2018)
Degrading quality of soil by the presence of xenobiotics or change in the natural environment of soil is of great concern. One of them is heavy metal pollution of soil. With increasing population, sustainable food production ...
Antibacterial and Anticancer property of bioactive secondary metabolites from Actinomycetes isolated from different regions of Himachal Pradesh
(Central University of Punjab, 2018)
The prime objective of the present work is to isolate, characterize and purify soil
microbes and to know about their antibacterial and anticancer properties. Soil
samples were obtained from different locations in Dharamsala, ...
Isolation And Determination Of Antibiotic Susceptibility Of Enterococcus Faecalis From Malwa Region
(Central University of Punjab, 2018)
About 20 isolates of Enterococcus faecalis is isolated from six different places of Malwa region. They include isolate from Animal waste soil, Agriculture soil, Sewage soil and public place soil also. Isolation of Enterococcus ...
Production and Optimization of Lovastatin by Microbial Fermentation using Aspergillus terreus
(Central University of Punjab, 2018)
In the recent times, the fungus Aspergillus (A.) terreus has been highly popularized regarding its domination for the production of the "crackerjack" drugs known as statins, particularly lovastatin. The aim of this research ...
Comparison of Pyruvate Kinase of different species of Lactic Acid Bacteria
(Central University of Punjab, 2018)
Pyruvate kinase (PK) is an important allosterically regulated enzyme that connects Glycolysis from the primary energy to cellular metabolism. It catalyzes the last step of Glycolysis by producing one mole of energy in the ...