Browsing Human Genetics and Molecular Medicine-Master Dissertation by Title
Now showing items 15-19 of 19
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Literature survey of HDACs in cancer and in-vitro analysis of HDAC inhibitor mediated chemo-sensitization
(Central University of Punjab, 2018)HDACs are chromatin modifying enzymes and post translational modifiers regulating transcription and activity of various proteins such as tubulin, Hsp90 and cortactin respectively. HDAC is divided into four classes (Class ... -
Meta-analysis and estimation of gene expression to establish the role of SFTPD in COPD
(Central University of Punjab, 2018)COPD is considered to be third leading cause of death by 2020. So far, there is no proper biomarker available for the diagnosis of all the different sub-phenotypes. Multiple GWAS studies have reported the role of SFTPD ... -
Potential Mitochondrial-Specific Function Of piRNAs
(Central University of Punjab, 2018)Piwi-interacting RNAs (piRNAs) are (26-31 nt) small noncoding RNAs processed from their longer precursor transcripts with the help of Piwi proteins. There are more than 30,000 piRNA genes present in the human genome which ... -
Psychological Burden Faced By Vitiligo Patients: A Comparative Study In Kerala And Punjab
(Central University of Punjab, 2018)Vitiligo is a common chronic skin disease having unknown aetiology, which causes a disfigurement and variable amount of skin and hair depigmentation and may affect a patient?s quality of life. To assess the psychological ... -
Study the effect of phytochemicals phenethyl isothiocyanate (PEITC) and Quercetin on mitochondrial biogenesis in cancer and normal cell lines
(Central University of Punjab, 2018)Phytochemicals are plant-derived chemicals generally are biologically active compounds and mediate positive health benefits by targeting genes or metabolic pathways of a cell. The phytochemicals examined can be classified ...