| dc.description.abstract | COPD is characterized by increasing breathlessness. It is the fourth cause of death in
the world and it is currently presenting a major global public health challenge, causing
premature death from pathophysiological complications. It continues to be an
important cause of morbidity, mortality, and health-care costs worldwide. It is a global
health issue, with cigarette smoking being an important risk factor universally with
several other factors, such as exposure to indoor and outdoor air pollution,
occupational hazards, and infections. As the global population ages, the burden of
COPD will increase in years to come. Folic acid or vitamin B9 is a water soluble
vitamin plays a major role in metabolism. Since, COPD is a disease characterized by
complex nutritional abnormalities and lower level of vitamin B9 and B12.
Homocysteine or total homocysteine is a sulfur containing amino acid, acts as an
intermediate in the metabolism of methionine in the folic acid or folate pathway. As
observed among general population hyperhomocysteinaemia (mild to moderate), is
mainly associated with vitamin B deficiencies, which are considered to be essential
cofactors for the level and catabolism of hcy. Assessment of level of micronutrients is
useful in establishing effects in COPD. | en_US |
