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Synthesis, Characterization and Biological Evaluation of 5-(2- Nitrophenyl)-1H-Pyrazole Derivatives as Putative Antiproliferative Agents

dc.contributor.authorSaini, Geetika
dc.date.accessioned2018-08-31T04:13:48Z
dc.date.available2018-08-31T04:13:48Z
dc.date.issued2018
dc.identifier.citationSaini, Geetika (2018) Synthesis, Characterization and Biological Evaluation of 5-(2- Nitrophenyl)-1H-Pyrazole Derivatives as Putative Antiproliferative Agentsen_US
dc.identifier.urihttp://kr.cup.edu.in/handle/32116/1931
dc.description.abstractPyrazoles are known to exhibit various biological activities like antibacterial, antiprotozoal, anticonvulsant, analgesic, anti-inflammatory, antiviral and antiproliferative. An attempt has been made to synthesize substituted pyrazoles. Their antiproliferative activity was determined by performing MTT assay on MDA-MB 231 cell line (breast cancer). The compounds were further docked into topoisomerase 1 and 2en_US
dc.language.isoen_USen_US
dc.publisherCentral University of Punjaben_US
dc.subjectCanceren_US
dc.subjectTopoisomeraseen_US
dc.subjectPyrazoleen_US
dc.subjectAntiproliferativeen_US
dc.subjectSynthesisen_US
dc.titleSynthesis, Characterization and Biological Evaluation of 5-(2- Nitrophenyl)-1H-Pyrazole Derivatives as Putative Antiproliferative Agentsen_US
dc.typeMaster Dissertationen_US
dc.contributor.supervisorKumar, Raj
dc.identifier.accessionnoT00630


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