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dc.contributor.authorPramanik S.
dc.contributor.authorAgarwala P.
dc.contributor.authorVasudevan K.
dc.contributor.authorSarkar K.
dc.date.accessioned2020-01-31T11:34:00Z
dc.date.available2020-01-31T11:34:00Z
dc.date.issued2019
dc.identifier.issn218995
dc.identifier.urihttp://kr.cup.edu.in/handle/32116/2567
dc.description.abstractBiodegradable starch (Str) polymer was derived from potato, a plant-based natural carbohydrate polymers source, by one-pot synthesis. Hydroxyapatite (HA) was produced from goat bone by step sintering. The inexpensive starch/HA thin film composites were fabricated by customized spin coating. This study revealed that the hydrogen bond energy and distance have significant effect on glass transition temperature of the polymer. The 40 wt % HA contained starch (StrHA40) composite thin film showed excellent tensile strength (3.03 + ?0.03 MPa), elongation (21.5 + ?5.5%) and modulus (15.5 + ?0.2 MPa) closed to human skin. The in vitro swelling and biodegradation kinetics of pristine starch and pure HA has been controlled and improved by using suitable composition. This study postulated the probable water molecule-adsorption mechanisms of pristine starch and starch/HA composite films. The StrHA40 composite showed excellent biocompatibility to the human-blood derived lymphocyte cells. Therefore, the starch/HA thin film composite-based biodegradable scaffolds developed in the present study can be an excellent potential candidate for soft tissue regeneration and/or replacement applications. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 137, 48913.en_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.subjectbiodegradableen_US
dc.subjectbiomedical applicationsen_US
dc.subjectdifferential scanning calorimetry (DSC)en_US
dc.subjectglass transitionen_US
dc.subjectsynthesis and processing techniquesen_US
dc.titleHuman-lymphocyte cell friendly starch-hydroxyapatite biodegradable composites: Hydrophilic mechanism, mechanical, and structural impacten_US
dc.typeArticleen_US
dc.identifier.doi10.1002/app.48913
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/full/10.1002/app.48913
dc.title.journalJournal of Applied Polymer Scienceen_US
dc.type.accesstypeClose Accessen_US


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