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Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes
(2012)
Cancer cells reflect higher level of ROS in comparison to the normal cell, so they become more vulnerable to further oxidative stress induced by exogenous ROS-generating agents. Through this a novel therapeutic strategy ...
Temperature-stratified screening of chickpea (Cicer arietinum L.) genetic resource collections reveals very limited reproductive chilling tolerance compared to its annual wild relatives
(2012)
Low reproductive chilling tolerance in chickpea impairs ovule fertilization, delaying pod set, exposing the crop to terminal drought throughout much of its distribution range. Despite this realization, little progress has ...
Systematics and Taxonomic Keys for the Marine Green Algal Family Monostromataceae
(Nova Science Publishers, 2012)
Marine green algal family Monostromataceae consists of single cell-layered green seaweeds distributed throughout the world, yet identification of it being one of the most challenging. Monostromatic green seaweeds are all ...
Cancer phylogenetics: Computational modeling of tumor evolution
(Nova Science Publishers, Inc., 2012)
The field of phylogenetics is one of the core areas of Bioinformatics which deals with computational methods to infer evolutionary heritage of organisms and genes. While phylogenetics has been extensively utilized in ...
Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles
(2012)
Silver nanoparticles (Ag NPs) are used in consumer products and wound dressings due to their antimicrobial properties. However, in addition to toxic effects on microbes, Ag NPs can also induce stress responses as well as ...
Conflict and peace in Eurasia
(Taylor and Francis, 2012)
Focusing on a range of Eurasian conflicts, including Nagorno-Karabakh, South Ossetia and Abkhazia, this book offers contemporary perspectives on the ongoing conflicts in the Eurasia, with an emphasis on the attempts towards ...
Chromosomal location of non-hypersensitive leaf rust resistance genes in bread wheat cultivar PBW65 using microsatellite markers
(2012)
Microsatellite or simple sequence repeat (SSRs) markers have been powerful tool for genetic mapping in wheat. Indian bread wheat (Triticum aestivum L.) cultivar PBW65 has shown significant level of resistance to most ...
Insulin resistance induces a segmental difference in thoracic and abdominal aorta: Differential expression of AT1 and AT2 receptors
(2012)
Objectives: The study was pursued to understand and compare the vascular reactivity to angiotensin II (Ang II) and its receptor expression in thoracic and abdominal aorta under insulin resistance. Methods: Vascular reactivity ...
To Study the Dose and Time Dependent Effect of Human Insulin and Metformin on the Growth of Breast Cancer Cells
(Central University of Punjab, 2012)
Cancer and diabetes, both are leading causes of mortality globally. Both the diseases
are multifactorial and share number of common risk factors. Hyperglycemia and
hyperinsulinemia which are the characteristic features ...
To study the effect of insulin on advanced androgen-indpendent prostate cancer (pc-3) cells
(Central University of Punjab, 2012)
Prostate cancer is one of the major causes of mortality in males over the age of fifty all over the world. Many factors including genetics and diet have been associated with the development of prostate cancer. Hyperinsulinemia ...