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In silico study of flavonoids as DPP-4 and α-glucosidase inhibitors
(Bentham Science Publishers B.V., 2018)
Background: Diabetes being among the most prevalent disease is being studied widely to achieve most potent drug with lesser side-effects. Numerous targets have been explored and several drugs have been developed to combat ...
Multitargeted molecular docking study of natural-derived alkaloids on breast cancer pathway components
(Bentham Science Publishers B.V., 2017)
Background: Targeting of multiple sites is a pharmacologically, pharmacokinetic and dynamically more acceptable approach for complex diseases such as BC. It is recommended that the women who are at high risk of developing ...
In silico screening and molecular interaction studies of tetrahydrocannabinol and its derivatives with acetylcholine binding protein
(Bentham Science Publishers B.V., 2018)
Background: Alzheimer’s disease (AD) is the fourth largest cause of death among people over 65 years of age. Accumulation of β-amyloid and cholinergic deficiency are two prominent pathological descriptions for AD.
Objective: ...
Gene and metabolite profiling reveals flowering and survival strategies in Himalayan Rhododendron arboreum
(Elsevier, 2019)
Rhododendron arboreum inhabits the Himalayan climate otherwise detrimental to many species, though the underlying survival mechanism remains unclear. Such temperate species have an inherent endurance towards freezing ...
Chemical composition and biological effects of Artemisia essential oils from Western Himalaya
(Theime, 2014)
Artemisia species possess pharmacological properties that are used for medical purposes worldwide. In this paper, the essential oils from the aerial parts of Artemisia nilagirica and Artemisia maritima from the western ...
Drug Targeting Strategies in Breast Cancer Treatment
(Bentham Science, 2014)
Breast cancer (BC) is the leading cause of death among women all over the world. Estrogen receptor (ER) based therapy is one of the major approaches to target BC and is associated with various problems such as primary as ...
Chemical composition and biological activity of essential oils of dracocephalum heterophyllum benth And Hyssopus officinalis L Collected wild from Western Himalay
(Sage, 2015)
The essential oils of two representatives of the Lamiaceae, Dracocephalum heterophyllum Benth. and Hyssopus officinalis L., are described for their antifungal, antibacterial, larvicidal and inect biting deterrent activities. ...
Essential Oils: An Impending Substitute of Synthetic Antimicrobial Agents to Overcome Antimicrobial Resistance
(Bentham Science, 2019)
ntimicrobial resistance (AMR) is an emerging problem in the world that has a significant impact on our society. AMR made conventional drugs futile against microorganisms and diseases untreatable. Plant-derived medicines ...
Coumarin Derivatives as Anticancer Agents for Lung Cancer Therapy: A Review.
(Bentham Science, 2018)
Background: The prevalence of lung cancer is 14% among the newly diagnosed cancer cases worldwide. Currently, the number of drugs that are in clinical practice is having a high prevalence of side effect and multidrug ...