Browsing School of Health Sciences by Title

Now showing items 269-288 of 397

    • Nanotheranostics revolutionizing neurodegenerative diseases: From precision diagnosis to targeted therapies 

      Joshi, Riya; Missong, Hemi; Mishra, Jayapriya; Kaur, Satinder; Saini, Sumant; Kandimalla, Ramesh; Reddy, P. Hemachandra; Babu, Arockia; Bhatti, Gurjit Kaur; Bhatti, Jasvinder Singh (Editions de Sante, 2023-10-16)
      Neurodegenerative disorders pose a significant burden on global healthcare systems, and the development of effective therapeutics and diagnostics remains a critical challenge. Nanotheranostics, the integration of ...

    • Nanotherapeutics for Parkinson's disease using metal nanocomposites 

      Dhapola, Rishika; Sharma, Prajjwal; Kumari, Sneha; Nagar, Pushank; Medhi, Bikash; Reddy, Dibbanti Harikrishna (CRC Press, 2023-10-19)
      [No abstract available]

    • Natural Compound-Based Nanoparticles to Target Free Radicals in Cancer 

      Yadav, Umesh Prasad; Rhuthuparna, M.; Vasudeva, Kanika; Suman, Prabhat; Munshi, Anjana; Kumar, Santosh; Singh, Sandeep (Springer Singapore, 2022-09-28)
      Cell proliferation and malignant transformation are enabled by genetic and epigenetic changes. During the malignancy process, malignant cells acquire distinguishing characteristics. Cancer cells have acquired the ability ...

    • Natural Compounds as Potential Anti-COVID Agents 

      Rani, Nidhi; Singh, Randhir; Kumar, Praveen; Sharma, Prerna; Sharma, Vikas (Bentham Science Publishers, 2022-04-05)
      Background: Since December 2019, COVID-19 has become a new health crisis in the world and has been declared a public health emergency of international concern by WHO. In search of anti-COVID treatment regimen, we applied ...

    • Natural Products as an Alternative Therapy for Brain Tumors: From Bench To Bedside 

      Kumar, Sachin; Kumar, Mandeep; Bijalwan, Anjali; Sharma, Shubham; Kumar, Puneet (Springer Singapore, 2022-09-28)
      Incremental elevation in the trends of a brain tumor in recent years accounts for 5% adult population, whereas the number exceeds 70% in the case of children. Evidence reveals an eventual metastasize of 20%-30% of malignant ...

    • Neurobiology of traumatic brain injury 

      Bagri, Kajal; Kumar, Puneet; Deshmukh, Rahul (Taylor and Francis Ltd., 2021-09-06)
      Traumatic brain injury (TBI) involves structural damage to the brain regions causing death or disability in patients with lifelong sufferings. Accidental injuries to the brain, besides structural damage, if any, cause ...

    • Neurodegenerative diseases and brain delivery of therapeutics: Bridging the gap using dendrimers 

      Kaur, Amandeep; Singh, Navneet; Kaur, Harmanpreet; Kakoty, Violina; Sharma, Deep Shikha; Khursheed, Rubiya; Babu, Molakpogu Ravindra; Harish, Vancha; Gupta, Gaurav; Gulati, Monica; Kumar, Puneet; Dureja, Harish; Alharthi, Nahed S.; Khan, Farhan R.; Rehman, Zia ur; Hakami, Mohammed Ageeli; Patel, Mrunali; Patel, Rashmin; Zandi, Milad; Vishwas, Sukriti; Dua, Kamal; Singh, Sachin Kumar (Editions de Sante, 2023-08-26)
      Neurodegenerative diseases (NDs) continue to burden human lives and economic conditions. They continue to challenge the healthcare system due to the associated physiological barriers. Traditional treatment approaches are ...

    • Neuroimaging Genomics a Predictor of Major Depressive Disorder (MDD) 

      Jindal, Manav; Chhetri, Aakash; Ludhiadch, Abhilash; Singh, Paramdeep; Peer, Sameer; Singh, Jawahar; Brar, Rahatdeep Singh; Munshi, Anjana (Springer, 2023-11-22)
      Depression is a complex psychiatric disorder influenced by various genetic and environmental factors. Strong evidence has established the contribution of genetic factors in depression through twin studies and the heritability ...

    • Neuroinflammation in Alzheimer�s Disease: Current Progress in Molecular Signaling and Therapeutics 

      Thakur, Sujata; Dhapola, Rishika; Sarma, Phulen; Medhi, Bikash; Reddy, Dibbanti HariKrishna (Springer, 2022-08-20)
      Alzheimer�s disease, a neurodegenerative disease with amyloid beta accumulation as a major hallmark, has become a dire global health concern as there is a lack of clear understanding of the causative agent. It is a major ...

    • Neuroprotection through G-CSF: recent advances and future viewpoints 

      Rahi, Vikrant; Jamwal, Sumit; Kumar, Puneet (Springer Science and Business Media Deutschland GmbH, 2021-01-02)
      Granulocyte-colony stimulating factor (G-CSF), a member of the cytokine family of hematopoietic growth factors, is 19.6�kDa glycoprotein which is responsible for the proliferation, maturation, differentiation, and survival ...

    • Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats 

      Kaur, Amandeep; Jaiswal, Gagandeep; Brar, Jasdeep; Kumar, Puneet (Oxford University Press, 2020-11-26)
      Traumatic brain injury (TBI) is an insult to the brain from an external mechanical force, leading to temporary/permanent secondary injuries, i.e. impairment of cognitive, physical, and psycho-social functions with altered ...

    • Neuroprotective effect of silymarin against 3-Nitropropionic acid-induced neurotoxicity in rats 

      Chandolia, Priyanka; Rahi, Vikrant; Kumar, Puneet (Elsevier B.V., 2022-09-20)
      (HD) Huntington's disease is a severe hereditary catastrophic neurological disease with an autosomal dominant heritable changes manifested by cognitive, behavioural, and motor progression deficits, resulting in death. ...

    • Neuroprotective potential of Moringa oleifera mediated by NF-kB/Nrf2/HO-1 signaling pathway: A review 

      Mundkar, Maroti; Bijalwan, Anjali; Soni, Divya; Kumar, Puneet (John Wiley and Sons Inc, 2022-10-07)
      Moringa oleifera is a traditional Indian herb belonging to the Moringaceae family, it is commonly known as the horse-radish tree, drumstick, or sahajna. In developing countries, Moringa is used as feed for both humans and ...

    • Neuroprotective role of apocynin against pentylenetetrazole kindling epilepsy and associated comorbidities in mice by suppression of ROS/RNS 

      Jaiswal, Gagandeep; Kumar, Puneet (Elsevier B.V., 2021-11-30)
      Epilepsy is a neurological disease that transpires due to the unusual synchronized neuronal discharge within the central nervous system, which drives repetitious unprovoked seizures. Nicotinamide adenine dinucleotide ...

    • A novel 7 bp deletion in PRPF31 associated with autosomal dominant retinitis pigmentosa with incomplete penetrance in an Indian family 

      Saini, S.; Robinson, P.N.; Singh, J.R.; Vanita, V. (2012)
      To localize and identify the gene linked with non-syndromic autosomal dominant retinitis pigmentosa (adRP) with high but not complete penetrance in an Indian family. A detailed family history and clinical data were recorded. ...

    • Novel pharmacological approaches for diabetic complications 

      Arora, Anchal; Navik, Uma Shanker; Jaiswal, Aiswarya; Kaur, Prabhsharan; Kumar, Puneet (Nova Science Publishers, Inc., 2021-03-24)
      Diabetes is a chronic illness characterized by uncontrolled hyperglycemia, disturbances in carbohydrate, and lipid and protein metabolism due to impaired function of insulin-secreting pancreatic ?-cell, insulin action or ...

    • Nutrition and neurological disorders 

      Sharma, Prerna; Gangwar, Aishwarya; Rani, Nidhi; Singh, Randhir (Elsevier, 2023-06-16)
      Nutritional intakes, homeostasis of glucose and also of electrolytes, are controlled by the central nervous system which triggers the various sensations. Certain risks are associated with malnutrition that may have severe ...

    • Obesity-Induced Chronic Low-Level Inflammation and Cancers 

      Bhattacharya, Neetu; Maurya, Shashank Kumar; Bhattacharya, Amit; Senapati, Sabyasachi (Springer Singapore, 2021-07-18)
      The World Health Organization (WHO) has highlighted �overweight and obesity� as a public health concern and a significant risk factor for several chronic diseases, including diabetes, cardiovascular diseases, and cancers. ...

    • Oncogenic metabolic reprogramming in breast cancer: focus on signaling pathways and mitochondrial genes 

      Malayil, Rhuthuparna; Chhichholiya, Yogita; Vasudeva, Kanika; Singh, Harsh Vikram; Singh, Tashvinder; Singh, Sandeep; Munshi, Anjana (Springer, 2023-05-11)
      Oncogenic metabolic reprogramming impacts the abundance of key metabolites that regulate signaling and epigenetics. Metabolic vulnerability in the cancer cell is evident from the Warburg effect. The research on metabolism ...

    • Opportunities and challenges in application of artificial intelligence in pharmacology 

      Kumar, Mandeep; Nguyen, T. P. Nhung; Kaur, Jasleen; Singh, Thakur Gurjeet; Soni, Divya; Singh, Randhir; Kumar, Puneet (Springer Science and Business Media Deutschland GmbH, 2023-01-09)
      Artificial intelligence (AI) is a machine science that can mimic human behaviour like intelligent analysis of data. AI functions with specialized algorithms and integrates with deep and machine learning. Living in the ...