Now showing items 1-9 of 15
Editorial: Signal Transduction Inhibitors as Promising Anticancer Agents
Cancer is a group of diseases sharing common features like unrestrictive growth, metastasis, and angiogenesis; however the basic signal transduction pathways are deregulated to such an extent that every cancer case itself ...
Oxidative stress and inflammation in diabetic complications
(Hindawi Publishing Corporation, 2014)
Fruit waste (peel) as bio-reductant to synthesize silver nanoparticles with antimicrobial, antioxidant and cytotoxic activities
(University of South Bohemia, 2018)
Since last decade, biogenic synthesis of metal or metal-oxide nanoparticles is emerging as an alternative method, which is environment friendly, simple and safe to use. In this article, fruit waste (peel) extract (FWE) of ...
1-Acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles: Exhibiting anticancer activity through intracellular ROS scavenging and the mitochondria-dependent death pathway
(Wiley-VCH Verlag, 2014)
A series of 17 analogs of 1-acetyl-4,5-dihydro(1H)pyrazoles (JP-1 to JP-17) bearing two aromatic rings at positions 3 and 5, either of which ought to be heterocyclic, were synthesized and evaluated for their anti-proliferative ...
Synthesis of imine-pyrazolopyrimidinones and their mechanistic interventions on anticancer activity
Design, synthesis and anticancer activity of a series of imine-pyrazolopyrimidinones is reported for the first time. Compounds 9d, 9n and 9o in the series show encouraging in vitro anticancer activity with low micromolar ...
CYP/PON genetic variations as determinant of organophosphate pesticides toxicity
(Springer India, 2017)
In the present scenario of increased accumulation of pesticides in the environment, it is important to understand its impact on human health. The focus is on gene?environment interaction, highlighting the consequences and ...
miR-30c and miR-181a synergistically modulate p53?p21 pathway in diabetes induced cardiac hypertrophy
(Springer New York LLC, 2016)
p53?p21 pathway mediates cardiomyocyte hypertrophy and apoptosis and is upregulated in diabetic cardiomyopathy (DbCM). We investigated role of microRNAs in regulating p53?p21 pathway in high glucose (HG)-induced cardiomyocyte ...
Dietary Patterns and Breast Cancer Risk: A Multi-Centre Case Control Study among North Indian Women
Evidence from India, a country with unique and distinct food intake patterns often characterized by lifelong adherence, may offer important insight into the role of diet in breast cancer etiology. We evaluated the association ...