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Serum Albumin Levels in Breast Cancer: Correlation with Overall Survival
(SciTechnol, 2017)
Introduction: Albumin in an important biomarker that indicates malnutrition as well as inflammation. The aim of the study was to evaluate the albumin levels in breast cancer patients and its association with overall survival ...
Role of p53 gene in breast cancer: Focus on mutation spectrum and therapeutic strategies
(Bentham Science Publishers B.V., 2018)
TP53 is a tumor suppressor gene which is commonly mutated in various cancers including breast cancer. Alterations in the gene lead to an altered expression of various genes that are directly or indirectly under the ...
Identification of Novel lncRNA in Breast Cancer Cell Line
(Central University of Punjab, 2018)
Long non-coding RNA(lncRNA) is RNA transcript having size of more 200 nucleotides and low number of exons are present due to which it expressed at lower level in specific tissues. Mainly the lncRNA is involved in gene ...
Eeffect of Natural Compounds on Her2 Expression
(Central University of Punjab, 2018)
Breast cancer is a heterogeneous disease that is challenging to treat.we examine potential natural compounds which may help in treating her2 positive breast cancer. The main objectives of this study are to determine the ...
Transcriptional Regulation of Pro-metastatic Protein Formin Binding Protein17 (FBP17) in Breast Cancer
(Central University of Punjab, 2018)
Breast cancer is a diverse disease with multiple subtypes. Among the different molecular subtypes, triple negative breast cancers (TNBC) harbor frequent mutation in tumor suppressor p53. Recently it was shown that p53 ...
Epidemiological factors, genetic and inflammatory markers in the development of Breast Cancer in Malwa region of Punjab
(Central University of Punjab, 2019)
Breast cancer is one of the most common malignancy among women and also the leading cause of death worldwide. Malwa region of Punjab is reported to have the highest number of cancer cases in comparison with the other two ...
Pharmacogenetics of Cyclophosphamide and Doxorubicin in Breast Cancer & Synthesis and Biological Evaluation of New Imidazole Based Putative Anticancer Agents
(Central University of Punjab, 2019)
Breast cancer is the second most prevalent cancer in women worldwide. It is treated by various strategies, including surgery, radiation therapy, hormonal therapy, targeted therapy and chemotherapy. Chemotherapeutic drugs ...
Association of elevated levels of C-reactive protein with breast cancer, breast cancer subtypes, and poor outcome
(Mosby Inc., 2019)
Background and Purpose: Inflammation and caner are linked in a bidirectional manner. C-reactive protein (CRP) is an important inflammatory marker. The aim of the study was to test whether the inflammatory marker, CRP at ...
Dietary Patterns and Breast Cancer Risk: A Multi-Centre Case Control Study among North Indian Women
(mdpi, 2018)
Evidence from India, a country with unique and distinct food intake patterns often characterized by lifelong adherence, may offer important insight into the role of diet in breast cancer etiology. We evaluated the association ...
Structural assembly of Polycomb group protein and Insight of EZH2 in cancer progression: A review
(Wolters Kluwer Medknow Publications, 2020-10-13)
Polycomb group proteins (PcG) are multi-subunit structure, consisting of polycomb repressive complex 1 (PRC1), PRC2/3, and pleiohomeotic repressive complex. PRC1 is made up of PHC, BMI-1, CBX, and Ring 1A/B. PRC2 protein ...