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Editorial: Novel biomarkers for type 2 diabetes
(Frontiers Media S.A., 2019)
[No abstract available]
Genetics of platelet traits in ischaemic stroke: focus on mean platelet volume and platelet count
(Taylor and Francis Ltd, 2019)
Purpose/Aim of the study: The aim of this review is to summarize the role of genetic variants affecting mean platelet volume (MPV) and platelet count (PLT) leading to higher platelet reactivity and in turn to thrombotic ...
Effect of TiO2 and Fe doped TiO2 nanoparticles on mitochondrial membrane potential in HBL-100 cells
(American Institute of Physics Inc., 2019)
Titanium dioxide (TiO2) nanoparticles (NPs) have made unbelievable progress in the field of nanotechnology and biomedical research. The proper toxicological assessment of TiO2 NPs and the reduction of its cytotoxicity need ...
ACE-Triggered Hypertension Incites Stroke: Genetic, Molecular, and Therapeutic Aspects
(Springer, 2019)
Stroke is the second largest cause of death worldwide. Angiotensin converting enzyme (ACE) gene has emerged as an important player in the pathogenesis of hypertension and consequently stroke. It encodes ACE enzyme that ...
Caulerpa taxifolia inhibits cell proliferation and induces oxidative stress in breast cancer cells
(De Gruyter, 2019)
Caulerpa taxifolia (M. Vahl) C. Agardh or killer alga is known to possess several bioactive secondary metabolites with unique structural modifications. We investigated anti-oxidant and anti-proliferative activity of C. ...
P53-mediated anticancer activity of Citrullus colocynthis extracts
(Bentham Science Publishers, 2019)
Background: Current anticancer therapeutics comes with significant side effects and thus focus is shifting towards minimizing the side effects or to avoid the disease altogether. Thus, various natural products are being ...
Small regulatory molecules acting big in cancer: Potential role of mito-miRs in cancer
(Bentham Science Publishers, 2019)
MicroRNAs [miRNAs] are short, non-coding, single stranded RNA molecules regulating gene expression of their targets at the posttranscriptional level by either degrading mRNA or by inhibiting translation. Previously, miRNAs ...
Association study identified biologically relevant receptor genes with synergistic functions in celiac disease
(NLM (Medline), 2019)
Receptors are essential mediators of cellular physiology, which facilitate molecular and cellular cross-talk with the environment. Nearly 20% of the all known celiac disease (CD) genes are receptors by function. We ...