Browsing by Author "Acharya, Varnali"

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    Clinical potential of long non-coding RNA LINC01133 as a promising biomarker and therapeutic target in cancers
    (Newlands Press Ltd, 2022-02-23T00:00:00) Sharma, Uttam; Barwal, Tushar Singh; Murmu, Masang; Acharya, Varnali; Pant, Neha; Dey, Damayanti; Vivek; Gautam, Ashima; Bazala, Sonali; Singh, Ipsa; Azzouz, Farah; Bishayee, Anupam; Jain, Aklank
    Recently, long intergenic non-protein coding RNA 01133 (LINC01133) was identified as a novel transcript in cancers. It modulates various hallmarks of cancers and acts as oncogenic in some cancers while tumor-suppressive in others. Furthermore, the expression of LINC01133 correlates with tumor size, advanced tumor node metastasis stage and lymphatic node metastasis, Ki-67 levels and overall survival of patients. Herein, the authors provide an in-depth analysis describing how LINC01133 modulates the multiple cancer-associated signaling pathways and the pathogenesis of various malignancies and treatment regimens. Based on the role played by LINC01133, the authors propose LINC01133 as both a potential biomarker and a therapeutic target in cancer. � 2022 Future Medicine Ltd.