Browsing by Author "Chattu, Vijay Kumar"
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Item Access to medicines through global health diplomacy(Tabriz University of Medical Sciences, 2023-06-10T00:00:00) Chattu, Vijay Kumar; Singh, Bawa; Pattanshetty, Sanjay; Reddy, SrikanthThe World Health Organisation (WHO) emphasizes that equitable access to safe and affordable medicines is vital to attaining the highest possible standard of health by all. Ensuring equitable access to medicines (ATM) is also a key narrative of the Sustainable Development Goals (SDGs), as SDG 3.8 specifies �access to safe, effective, quality and affordable essential medicines and vaccines for all� as a central component of universal health coverage (UHC). The SDG 3.b emphasizes the need to develop medicines to address persistent treatment gaps. However, around 2 billion people globally have no access to essential medicines, particularly in lower- and middle-income countries. The states� recognition of health as a human right obligates them to ensure access to timely, acceptable, affordable health care. While ATM is inherent in minimizing the treatment gaps, global health diplomacy (GHD) contributes to addressing these gaps and fulfilling the state�s embracement of health as a human right. � 2023 The Author(s).Item Advancing african medicines agency through global health diplomacy for an equitable pan-african universal health coverage: A scoping review(MDPI, 2021-11-09T00:00:00) Chattu, Vijay Kumar; Dave, Vishal B.; Reddy, K. Srikanth; Singh, Bawa; Sahiledengle, Biniyam; Heyi, Demisu Zenbaba; Nattey, Cornelius; Atlaw, Daniel; Jackson, Kioko; El-Khatib, Ziad; Eltom, Akram AliThe African continent is home to 15% of the world�s population and suffers from a disease burden of more than 25% globally. In this COVID-19 era, the high burden and mortality are further worsened due to inequities, inequalities such as inadequate health systems, scarce financial and human resources, as well as unavailability of inexpensive medicines of good quality, safety, and efficacy. The Universal Health Coverage ensures that people have access to high-quality essential health services, secure, reliable, and affordable essential medicines and vaccines, as well as financial security. This paper aimed at addressing the critical need for a continental African Medicines Agency (AMA) in addressing the inequities and the role of global health diplomacy in building consensus to support the ratification of the Treaty of AMA. A literature review was done in Scopus, Web of Science, MEDLINE/PubMed, and Google Scholar search engine to identify the critical literature in the context of study objectives. All the articles published after 2015 till 2021 in the context of AMA were included. African Health Strategy 2016�2030 highlighted the importance of an African regulatory mechanism for medicines and medical products. Through global health diplomacy (GHD), the African Union and its partners can negotiate and cooperate in providing infrastructural, administrative, and regulatory support for establishing the AMA. The paper emphasizes the South�South cooperation and highlights the contributions of India and China in the supply of medicines and vaccines to Africa. A strong AMA created through GHD can be a vital instrument in utilizing Trade-Related Aspects of Intellectual Property Rights (TRIPS) flexibilities extension and an ideal partner for European and other regional regulatory authorities seeking to stem the tide of counterfeit, sub-standard, or fake products. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.Item Barriers to Indo-Pak Trade: A Case Study of Land Routes(SAGE Publications Ltd, 2023-07-02T00:00:00) Zahid-ul-Islam-Dar; Kaur, Sandeep; Chattu, Vijay KumarConcerning land routes, the study aims to document some crucial barriers, which are relatively easy to address but potent enough to expand trade between India and Pakistan. Using field research, this article examines the factors that impede trade between India and Pakistan through land-border crossings�Attari�Wagah border in Punjab and, Chakkan da Bagh, Poonch, and Salamabad Uri, Baramulla, the two land-border crossings in Jammu and Kashmir. Semi-structured questionnaires are administered to traders and unstructured interviews are held with other stakeholders. The findings such as security issues, inadequate banking facilities, inadequate physical infrastructure, communication lacunae, excessive paperwork, and lack of arrangements for traders� meets are documented as some of the prominent impeding factors in overland trade between the two nations. The prominent barriers perceived by the traders concerning Attari and Cross-the Line of Control (LoC) trade are excessive documentation, complex procedures, and nonavailability of banking facilities. � 2023 Association of Asia Scholars.Item The Burden of Non-Communicable Diseases (NCDs) among Prisoners in India: A Systematic Review and Meta-Analysis(MDPI, 2022-10-18T00:00:00) Manna, Subhanwita; Tripathy, Snehasish; Sah, Rahul Kumar; Padhi, Bijaya Kumar; Kaur, Sandeep; Nowrouzi-Kia, Behdin; Chattu, Vijay KumarBackground: The increasing prevalence and subsequent mortality due to non-communicable diseases (NCDs) among Indian prisoners are often ignored by policymakers. This systematic review and meta-analysis aim to analyze the rising burden of Noncommunicable Diseases in Indian prisons and estimate the pooled prevalence of depression among Indian prisoners. Methods: A total 9 studies were chosen in accordance with PRISMA guidelines that investigated the burden of NCDs in Indian prisons and were published between January 2010 and August 2022. Statistical analysis was performed in STATA Version 16 software, and the funnel plot was used to identify publication bias. Results: A total of 167 articles were identified, and 9 were included in this analysis. The pooled prevalence of depression among prisoners was 48.78% (95% CI, 27.24�70.55%). According to the review, prisoners showed a significant prevalence of moderate to severe depression, dental caries, poor periodontal condition, and suicide ideation. This study is the first to analyze NCDs prevalence among Indian prisoners. Poor mental and dental health standards and the virtual absence of healthcare facilities necessitate governmental actions to boost inmates� health. It is essential to develop preventative interventions for this extremely isolated and vulnerable group in addition to diagnosing and treating noncommunicable diseases. Conclusions: Our study findings will enable decision-makers to structure and develop appropriate preventative and curative programs for inmates� general wellbeing. � 2022 by the authors.Item COVID-19 and Global Distributive Justice: �Health Diplomacy� of India and South Africa for the TRIPS waiver(SAGE Publications Ltd, 2022-01-19T00:00:00) Singh, Bawa; Chattu, Vijay Kumar; Kaur, Jaspal; Mol, Rajni; Gauttam, Priya; Singh, BalinderThe second wave of the COVID-19 pandemic had left heart-wrenching impacts on all facets of life in general and the availability, accessibility, and affordability of medicines and vaccines in particular. Rather, the world has been divided into two groups regarding access to medicine and vaccines as haves and have-nots. The rich countries had pre-ordered the vaccines of COVID-19 along with the holding of the same. The pandemic situation was further worsened, given the Trade-Related Intellectual Property Rights (TRIPS) in practice and restrictions on sharing technology of vaccines, medicines, and life-saving equipment. In this context, India and South Africa have proposed the joint proposal and garnered support for waiving off TRIPS to ensure equity, accessibility, and affordability of vaccines and the same as public goods. In this review, we emphasize that global justice is one of the important elements of normative international theories, which focus on all the moral obligations from the world�s rich to the world�s poor. The paper also questions and argues that if the rich countries fail to go by the principles of global justice, can the Indian and South African (SA) patent diplomacy play a catalyst role in global justice? The review concludes with an emphasis on global solidarity, and the acceptance of joint India�South Africa�s �patent diplomacy� for TRIPS waiver would result in mass production and fair distribution, making the COVID-19 medicines and technologies available to everyone regardless of their poor�rich status. � The Author(s) 2022.Item Covid-19 pandemic and reimagination of multilateralism through global health diplomacy(MDPI, 2021-10-21T00:00:00) Gupta, Nippun; Singh, Bawa; Kaur, Jaspal; Singh, Sandeep; Chattu, Vijay KumarThe ongoing pandemic COVID-19 has made it very clear that no one is safe until everyone is safe. But how can everyone be safe when the pandemic has broken every nerve of the economy and put an extra burden on the already crippled healthcare systems in low-income countries? Thus, the pandemic has changed the orientation of domestic as well as global politics, with many geopolitical shifts. The exponential growing infected cases and more than four million deaths has demanded a global response in terms of multilateralism. However, declining multilateralism and the need for its reforms was a much-delayed response. Given this context, this paper aimed to link the decline of multilateralism in the face of the pandemic by highlighting various instances of its failure and success; and highlighting the need for its revival. The article critically examines and evaluates the responses of multilateralism and global health diplomacy (GHD) during the pandemic. The ongoing black swan kind of event (an unexpected event) has obligated global leadership to think in terms of the revival of multilateralism through GHD. Historically, multilateralism through GHD has been shown to play an important role in managing and combating pandemics. The article further discusses various theoretical aspects such as sovereignty and hegemonic stability theory as reasons for the failing of multilateralism. The paper concludes by emphasizing the importance of foresight in reviving multilateralism in the pursuit of a more sustainable future. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.Item COVID-19 Vaccine, TRIPS, and Global Health Diplomacy: India's Role at the WTO Platform(Hindawi Limited, 2021-08-27T00:00:00) Chattu, Vijay Kumar; Singh, Bawa; Kaur, Jaspal; Jakovljevic, MihajloIn light of the devastation caused by COVID-19, the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) and vaccine research and development (R&D) have been occupying a prominent position in the field of global health diplomacy (GHD). Most countries, international organizations, and charitable organizations have been engaged in the R&D of COVID-19 vaccines to ensure timely affordability and accessibility to all countries. Concomitantly, the World Trade Organization (WTO) provides some provisions and enforcements regarding copyrights, patents, trademarks, geographical indications, and industrial designs. Given these safeguards, it is considered that intellectual property rights (IPRs) have become major barriers to the affordability and accessibility of vaccines/medicines/technology, particularly to the developing/least developed countries. Realizing the gravity of the pandemic impact, as well as its huge population and size, India has elevated this issue in its global health diplomacy by submitting a joint proposal with South Africa to the World Trade Organization (WTO) for a temporary waiver of IPRs to ensure timely affordability and accessibility of COVID-19 medical products to all countries. However, the issue of the temporary waive off had become a geopolitical issue. Countries that used to claim per se as strong advocates of human rights, egalitarianism, and healthy democracy have opposed this proposal. In this contrasting milieu, this paper is aimed at examining how the TRIPS has become a barrier for developing countries' development and distribution of vaccines/technology; secondly, how India strategizes its role in the WTO in pursuant of its global health diplomacy? We conclude that the IPRs regime should not become a barrier to the accessibility/affordability of essential drugs and vaccines. To ensure access, India needs to get more engaged in GHD with all the involved global stakeholders to get strong support for their joint proposal. The developed countries that rejected/resisted the proposal can rethink their full support. � 2021 Vijay Kumar Chattu et al.Item Crop insurance policies in india: An empirical analysis of pradhan mantri fasal bima yojana(MDPI, 2021-10-27T00:00:00) Kaur, Sandeep; Raj, Hem; Singh, Harpreet; Chattu, Vijay KumarIndia is home to over one-third of all undernourished children worldwide, and it ranks 94th out of 107 nations in the Global Hunger Index 2020. Instability in production and market risks make agriculture a risky business and directly affect farmers� income levels, thereby impacting food security. This review aimed to understand various features of different crop insurance policies in India and to analyze the Pradhan Mantri Fasal Bima Yojana�s (PMFBY) impacts on Indian farmers. A literature search was performed in all popular databases, including Scopus, Web of Science, ProQuest, AGRICOLA, AGRIS, and Google search engines, as well as annual Indian government reports. The keywords �Crop Insurance� OR �Pradhan Mantri Fasal Bima Yojana� OR �National Agriculture Schemes� AND �India� were searched to obtain relevant articles. By using cumulative data, we conducted a multiple regression analysis and a model was developed to estimate the effects of insurance characteristics on farmer coverage for the years 2017�2018 and 2018�2019. Agricultural insurance coverage under PMFBY remained low in terms of the number of farmers insured, the area insured, claims paid, and total farmers benefited. Compared to other schemes, the beneficiary and claim premium ratios were substantially lower under the PMFBY. The multiple regression analysis showed that farmers� premiums have a significant effect on the number of farmers insured over time, although the subsidies do not have a significant influence in farmers� insurance participation. Delays in claim settlement, the complexity of the system, and a lack of awareness among farmers are the major weaknesses of the PMFBY. Greater use of digital media could help spread awareness of these schemes among farmers. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.Item The double whammy of pandemic and war: A systematic review of india�s education diplomacy to address educational inequities in afghanistan(MDPI, 2021-10-18T00:00:00) Singh, Bawa; Kaur, Jaspal; Sen, Rajinder Kumar; Singh, Balinder; Chattu, Vijay KumarHigher education is considered an important tool for the overall development of any country, and it holds true in the context of Afghanistan as well. At the same time, a good eco-environment in terms of political will, leaders� farsighted vision, a fair budget, good infrastructure, and a good teaching community are some of the basic requirements for higher education to move in the direction of new and higher horizons. However, due to the ongoing war during the last couple of decades, the country�s education system has become out of reach for a substantial part of the population due to poverty, lack of infrastructure, refugees and internally displaced, digital division, etc., critically affecting the education equity. This systematic review examines India�s education diplomacy in addressing the inequities in Afghanistan�s education system and making them more equitable. Education was further dilapidated with the outbreak of the COVID-19 pandemic. Afghanistan is caught between a war and a pandemic and suffers from a double whammy in losses. Subsequently, given their chilling effects, higher education becomes devoid of multiples equities, including education. However, because of their historical and geo-civilizational ties, India has focused on development diplomacy in general and education diplomacy (E.D) in particular to improve educational infrastructures. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.Item Global vaccine inequities and multilateralism amid COVID-19: Reconnaissance of Global Health Diplomacy as a panacea?(Tabriz University of Medical Sciences, 2023-02-20T00:00:00) Singh, Bawa; Kaur, Jaspal; Chattu, Vijay KumarBackground: The ongoing COVID-19 pandemic has shown a crystal-clear warning that nobody will be safe until everybody is safe against the pandemic. However, how everyone is safe when the pandemic�s fat tail risks have broken every nerve of the global economy and healthcare facilities, including vaccine equity. Vaccine inequity has become one of the critical factors for millions of new infections and deaths during this pandemic. Against the backdrop of exponentially growing infected cases of COVID-19 along with vaccine in-equity, this paper will examine how multilateralism could play its role in mitigating vaccine equity through Global Health Diplomacy (GHD). Second, given the most affected developing countries� lack of participation in multilateralism, could GHD be left as an option in the worst-case scenario?. Methods: In this narrative review, a literature search was conducted in all the popular databases, such as Scopus, Web of Science, PubMed and Google search engines for the keywords in the context of developing countries and the findings are discussed in detail. Results: In this multilateral world, the global governance institutions in health have been monopolized by the global North, leading to COVID-19 vaccine inequities. GHD aids health protection and public health and improves international relations. Besides, GHD facilitates a broad range of stakeholders� commitment to collaborate in improving healthcare, achieving fair outcomes, achieving equity, and reducing poverty. Conclusion: Vaccine inequity is a major challenge of the present scenario, and GHD has been partly successful in being a panacea for many countries in the global south. � 2022 The Author(s).Item Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021(Elsevier B.V., 2023-06-23T00:00:00) Ong, Kanyin Liane; Stafford, Lauryn K.; McLaughlin, Susan A.; Boyko, Edward J.; Vollset, Stein Emil; Smith, Amanda E.; Dalton, Bronte E.; Duprey, Joe; Cruz, Jessica A.; Hagins, Hailey; Lindstedt, Paulina A.; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abate, Melsew Dagne; Abbasian, Mohammadreza; Abbasi-Kangevari, Zeinab; Abbasi-Kangevari, Mohsen; ElHafeez, Samar Abd; Abd-Rabu, Rami; Abdulah, Deldar Morad; Abdullah, Abu Yousuf Md; Abedi, Vida; Abidi, Hassan; Aboagye, Richard Gyan; Abolhassani, Hassan; Abu-Gharbieh, Eman; Abu-Zaid, Ahmed; Adane, Tigist Demssew; Adane, Denberu Eshetie; Addo, Isaac Yeboah; Adegboye, Oyelola A.; Adekanmbi, Victor; Adepoju, Abiola Victor; Adnani, Qorinah Estiningtyas Sakilah; Afolabi, Rotimi Felix; Agarwal, Gina; Aghdam, Zahra Babaei; Agudelo-Botero, Marcela; Arriagada, Constanza Elizabeth Aguilera; Agyemang-Duah, Williams; Ahinkorah, Bright Opoku; Ahmad, Danish; Ahmad, Rizwan; Ahmad, Sajjad; Ahmad, Aqeel; Ahmadi, Ali; Ahmadi, Keivan; Ahmed, Ayman; Ahmed, Ali; Ahmed, Luai A.; Ahmed, Syed Anees; Ajami, Marjan; Akinyemi, Rufus Olusola; Al Hamad, Hanadi; Al Hasan, Syed Mahfuz; AL-Ahdal, Tareq Mohammed Ali; Alalwan, Tariq A.; Al-Aly, Ziyad; AlBataineh, Mohammad T.; Alcalde-Rabanal, Jacqueline Elizabeth; Alemi, Sharifullah; Ali, Hassam; Alinia, Tahereh; Aljunid, Syed Mohamed; Almustanyir, Sami; Al-Raddadi, Rajaa M.; Alvis-Guzman, Nelson; Amare, Firehiwot; Ameyaw, Edward Kwabena; Amiri, Sohrab; Amusa, Ganiyu Adeniyi; Andrei, Catalina Liliana; Anjana, Ranjit Mohan; Ansar, Adnan; Ansari, Golnoosh; Ansari-Moghaddam, Alireza; Anyasodor, Anayochukwu Edward; Arabloo, Jalal; Aravkin, Aleksandr Y.; Areda, Demelash; Arifin, Hidayat; Arkew, Mesay; Armocida, Benedetta; Arnlov, Johan; Artamonov, Anton A.; Arulappan, Judie; Aruleba, Raphael Taiwo; Arumugam, Ashokan; Aryan, Zahra; Asemu, Mulu Tiruneh; Asghari-Jafarabadi, Mohammad; Askari, Elaheh; Asmelash, Daniel; Astell-Burt, Thomas; Athar, Mohammad; Athari, Seyyed Shamsadin; Atout, Maha Moh'd Wahbi; Avila-Burgos, Leticia; Awaisu, Ahmed; Azadnajafabad, Sina; Darshan, B.B.; Babamohamadi, Hassan; Badar, Muhammad; Badawi, Alaa; Badiye, Ashish D.; Baghcheghi, Nayereh; Bagheri, Nasser; Bagherieh, Sara; Bah, Sulaiman; Bahadory, Saeed; Bai, Ruhai; Baig, Atif Amin; Baltatu, Ovidiu Constantin; Baradaran, Hamid Reza; Barchitta, Martina; Bardhan, Mainak; Barengo, Noel C.; Barnighausen, Till Winfried; Barone, Mark Thomaz Ugliara; Barone-Adesi, Francesco; Barrow, Amadou; Bashiri, Hamideh; Basiru, Afisu; Basu, Sanjay; Basu, Saurav; Batiha, Abdul-Monim Mohammad; Batra, Kavita; Bayih, Mulat Tirfie; Bayileyegn, Nebiyou Simegnew; Behnoush, Amir Hossein; Bekele, Alehegn Bekele; Belete, Melaku Ashagrie; Belgaumi, Uzma Iqbal; Belo, Luis; Bennett, Derrick A.; Bensenor, Isabela M.; Berhe, Kidanemaryam; Berhie, Alemshet Yirga; Bhaskar, Sonu; Bhat, Ajay Nagesh; Bhatti, Jasvinder Singh; Bikbov, Boris; Bilal, Faiq; Bintoro, Bagas Suryo; Bitaraf, Saeid; Bitra, Veera R.; Bjegovic-Mikanovic, Vesna; Bodolica, Virginia; Boloor, Archith; Brauer, Michael; Brazo-Sayavera, Javier; Brenner, Hermann; Butt, Zahid A.; Calina, Daniela; Campos, Luciana Aparecida; Campos-Nonato, Ismael R.; Cao, Yin; Cao, Chao; Car, Josip; Carvalho, Marcia; Castaneda-Orjuela, Carlos A.; Catala-Lopez, Ferran; Cerin, Ester; Chadwick, Joshua; Chandrasekar, Eeshwar K.; Chanie, Gashaw Sisay; Charan, Jaykaran; Chattu, Vijay Kumar; Chauhan, Kirti; Cheema, Huzaifa Ahmad; Abebe, Endeshaw Chekol; Chen, Simiao; Cherbuin, Nicolas; Chichagi, Fatemeh; Chidambaram, Saravana Babu; Cho, William C. S.; Choudhari, Sonali Gajanan; Chowdhury, Rajiv; Chowdhury, Enayet Karim; Chu, Dinh-Toi; Chukwu, Isaac Sunday; Chung, Sheng-Chia; Coberly, Kaleb; Columbus, Alyssa; Contreras, Daniela; Cousin, Ewerton; Criqui, Michael H.; Cruz-Martins, Natalia; Cuschieri, Sarah; Dabo, Bashir; Dadras, Omid; Dai, Xiaochen; Damasceno, Albertino Antonio Moura; Dandona, Rakhi; Dandona, Lalit; Das, Saswati; Dascalu, Ana Maria; Dash, Nihar Ranjan; Dashti, Mohsen; Davila-Cervantes, Claudio Alberto; De la Cruz-Gongora, Vanessa; Debele, Gebiso Roba; Delpasand, Kourosh; Demisse, Fitsum Wolde; Demissie, Getu Debalkie; Deng, Xinlei; Denova-Gutierrez, Edgar; Deo, Salil V.; Dervi�evi?, Emina; Desai, Hardik Dineshbhai; Desale, Aragaw Tesfaw; Dessie, Anteneh Mengist; Desta, Fikreab; Dewan, Syed Masudur Rahman; Dey, Sourav; Dhama, Kuldeep; Dhimal, Meghnath; Diao, Nancy; Diaz, Daniel; Dinu, Monica; Diress, Mengistie; Djalalinia, Shirin; Doan, Linh Phuong; Dongarwar, Deepa; dos Santos Figueiredo, Francisco Winter; Duncan, Bruce B.; Dutta, Siddhartha; Dziedzic, Arkadiusz Marian; Edinur, Hisham Atan; Ekholuenetale, Michael; Ekundayo, Temitope Cyrus; Elgendy, Islam Y.; Elhadi, Muhammed; El-Huneidi, Waseem; Elmeligy, Omar Abdelsadek Abdou; Elmonem, Mohamed A.; Endeshaw, Destaw; Esayas, Hawi Leul; Eshetu, Habitu Birhan; Etaee, Farshid; Fadhil, Ibtihal; Fagbamigbe, Adeniyi Francis; Fahim, Ayesha; Falahi, Shahab; Faris, MoezAlIslam Ezzat Mahmoud; Farrokhpour, Hossein; Farzadfar, Farshad; Fatehizadeh, Ali; Fazli, Ghazal; Feng, Xiaoqi; Ferede, Tomas Y.; Fischer, Florian; Flood, David; Forouhari, Ali; Foroumadi, Roham; Koudehi, Masoumeh Foroutan; Gaidhane, Abhay Motiramji; Gaihre, Santosh; Gaipov, Abduzhappar; Galali, Yaseen; Ganesan, Balasankar; Garcia-Gordillo, M.A.; Gautam, Rupesh K.; Gebrehiwot, Mesfin; Gebrekidan, Kahsu Gebrekirstos; Gebremeskel, Teferi Gebru; Getacher, Lemma; Ghadirian, Fataneh; Ghamari, Seyyed-Hadi; Nour, Mohammad Ghasemi; Ghassemi, Fariba; Golechha, Mahaveer; Goleij, Pouya; Golinelli, Davide; Gopalani, Sameer Vali; Guadie, Habtamu Alganeh; Guan, Shi-Yang; Gudayu, Temesgen Worku; Guimaraes, Rafael Alves; Guled, Rashid Abdi; Gupta, Rajeev; Gupta, Kartik; Gupta, Veer Bala; Gupta, Vivek Kumar; Gyawali, Bishal; Haddadi, Rasool; Hadi, Najah R.; Haile, Teklehaimanot Gereziher; Hajibeygi, Ramtin; Haj-Mirzaian, Arvin; Halwani, Rabih; Hamidi, Samer; Hankey, Graeme J.; Hannan, Md Abdul; Haque, Shafiul; Harandi, Hamid; Harlianto, Netanja I.; Mahmudul Hasan, S.M.; Hasan, Syed Shahzad; Hasani, Hamidreza; Hassanipour, Soheil; Hassen, Mohammed Bheser; Haubold, Johannes; Hayat, Khezar; Heidari, Golnaz; Heidari, Mohammad; Hessami, Kamran; Hiraike, Yuta; Holla, Ramesh; Hossain, Sahadat; Hossain, Md Shakhaoat; Hosseini, Mohammad-Salar; Hosseinzadeh, Mehdi; Hosseinzadeh, Hassan; Huang, Junjie; Huda, Md Nazmul; Hussain, Salman; Huynh, Hong-Han; Hwang, Bing-Fang; Ibitoye, Segun Emmanuel; Ikeda, Nayu; Ilic, Irena M.; Ilic, Milena D.; Inbaraj, Leeberk Raja; Iqbal, Afrin; Islam, Sheikh Mohammed Shariful; Islam, Rakibul M.; Ismail, Nahlah Elkudssiah; Iso, Hiroyasu; Isola, Gaetano; Itumalla, Ramaiah; Iwagami, Masao; Iwu, Chidozie C. D.; Iyamu, Ihoghosa Osamuyi; Iyasu, Assefa N.; Jacob, Louis; Jafarzadeh, Abdollah; Jahrami, Haitham; Jain, Rajesh; Jaja, Chinwe; Jamalpoor, Zahra; Jamshidi, Elham; Janakiraman, Balamurugan; Jayanna, Krishnamurthy; Jayapal, Sathish Kumar; Jayaram, Shubha; Jayawardena, Ranil; Jebai, Rime; Jeong, Wonjeong; Jin, Yinzi; Jokar, Mohammad; Jonas, Jost B.; Joseph, Nitin; Joseph, Abel; Joshua, Charity Ehimwenma; Joukar, Farahnaz; Jozwiak, Jacek Jerzy; Kaambwa, Billingsley; Kabir, Ali; Kabthymer, Robel Hussen; Kadashetti, Vidya; Kahe, Farima; Kalhor, Rohollah; Kandel, Himal; Karanth, Shama D.; Karaye, Ibraheem M.; Karkhah, Samad; Katoto, Patrick D. M. C.; Kaur, Navjot; Kazemian, Sina; Kebede, Sewnet Adem; Khader, Yousef Saleh; Khajuria, Himanshu; Khalaji, Amirmohammad; Khan, Moien A. B.; Khan, Maseer; Khan, Ajmal; Khanal, Saval; Khatatbeh, Moawiah Mohammad; Khater, Amir M.; Khateri, Sorour; Khorashadizadeh, Fatemeh; Khubchandani, Jagdish; Kibret, Biruk Getahun; Kim, Min Seo; Kimokoti, Ruth W.; Kisa, Adnan; Kivimaki, Mika; Kolahi, Ali-Asghar; Komaki, Somayeh; Kompani, Farzad; Koohestani, Hamid Reza; Korzh, Oleksii; Kostev, Karel; Kothari, Nikhil; Koyanagi, Ai; Krishan, Kewal; Krishnamoorthy, Yuvaraj; Defo, Barthelemy Kuate; Kuddus, Mohammed; Kuddus, Md Abdul; Kumar, Rakesh; Kumar, Harish; Kundu, Satyajit; Kurniasari, Maria Dyah; Kuttikkattu, Ambily; Vecchia, Carlo La; Lallukka, Tea; Larijani, Bagher; Larsson, Anders O.; Latief, Kamaluddin; Lawal, Basira Kankia; Le, Thao Thi Thu; Le, Trang Thi Bich; Lee, Shaun Wen Huey; Lee, Munjae; Lee, Wei-Chen; Lee, Paul H.; Lee, Sang-Woong; Lee, Seung Won; Legesse, Samson Mideksa; Lenzi, Jacopo; Li, Yongze; Li, Ming-Chieh; Lim, Stephen S.; Lim, Lee-Ling; Liu, Xuefeng; Liu, Chaojie; Lo, Chun-Han; Lopes, Graciliana; Lorkowski, Stefan; Lozano, Rafael; Lucchetti, Giancarlo; Maghazachi, Azzam A.; Mahasha, Phetole Walter; Mahjoub, Soleiman; Mahmoud, Mansour Adam; Mahmoudi, Razzagh; Mahmoudimanesh, Marzieh; Mai, Anh Tuan; Majeed, Azeem; Sanaye, Pantea Majma; Makris, Konstantinos Christos; Malhotra, Kashish; Malik, Ahmad Azam; Malik, Iram; Mallhi, Tauqeer Hussain; Malta, Deborah Carvalho; Mamun, Abdullah A.; Mansouri, Borhan; Marateb, Hamid Reza; Mardi, Parham; Martini, Santi; Martorell, Miquel; Marzo, Roy Rillera; Masoudi, Reza; Masoudi, Sahar; Mathews, Elezebeth; Maugeri, Andrea; Mazzaglia, Giampiero; Mekonnen, Teferi; Meshkat, Mahboobeh; Mestrovic, Tomislav; Jonasson, Junmei Miao; Miazgowski, Tomasz; Michalek, Irmina Maria; Minh, Le Huu Nhat; Mini, G.K.; Miranda, J. Jaime; Mirfakhraie, Reza; Mirrakhimov, Erkin M.; Mirza-Aghazadeh-Attari, Mohammad; Misganaw, Awoke; Misgina, Kebede Haile; Mishra, Manish; Moazen, Babak; Mohamed, Nouh Saad; Mohammadi, Esmaeil; Mohammadi, Mohsen; Mohammadian-Hafshejani, Abdollah; Mohammadshahi, Marita; Mohseni, Alireza; Mojiri-Forushani, Hoda; Mokdad, Ali H.; Momtazmanesh, Sara; Monasta, Lorenzo; Moniruzzaman, Md; Mons, Ute; Montazeri, Fateme; Ghalibaf, AmirAli Moodi; Moradi, Yousef; Moradi, Maryam; Sarabi, Mostafa Moradi; Morovatdar, Negar; Morrison, Shane Douglas; Morze, Jakub; Mossialos, Elias; Mostafavi, Ebrahim; Mueller, Ulrich Otto; Mulita, Francesk; Mulita, Admir; Murillo-Zamora, Efren; Musa, Kamarul Imran; Mwita, Julius C.; Nagaraju, Shankar Prasad; Naghavi, Mohsen; Nainu, Firzan; Nair, Tapas Sadasivan; Najmuldeen, Hastyar Hama Rashid; Nangia, Vinay; Nargus, Shumaila; Naser, Abdallah Y.; Nassereldine, Hasan; Natto, Zuhair S.; Nauman, Javaid; Nayak, Biswa Prakash; Ndejjo, Rawlance; Negash, Hadush; Negoi, Ruxandra Irina; Nguyen, Hau Thi Hien; Nguyen, Dang H.; Nguyen, Phat Tuan; Nguyen, Van Thanh; Nguyen, Hien Quang; Niazi, Robina Khan; Nigatu, Yeshambel T.; Ningrum, Dina Nur Anggraini; Nizam, Muhammad A.; Nnyanzi, Lawrence Achilles; Noreen, Mamoona; Noubiap, Jean Jacques; Nzoputam, Ogochukwu Janet; Nzoputam, Chimezie Igwegbe; Oancea, Bogdan; Odogwu, Nkechi Martina; Odukoya, Oluwakemi Ololade; Ojha, Vivek Anand; Okati-Aliabad, Hassan; Okekunle, Akinkunmi Paul; Okonji, Osaretin Christabel; Okwute, Patrick Godwin; Olufadewa, Isaac Iyinoluwa; Onwujekwe, Obinna E.; Ordak, Michal; Ortiz, Alberto; Osuagwu, Uchechukwu Levi; Oulhaj, Abderrahim; Owolabi, Mayowa O.; Padron-Monedero, Alicia; Padubidri, Jagadish Rao; Palladino, Raffaele; Panagiotakos, Demosthenes; Panda-Jonas, Songhomitra; Pandey, Ashok; Pandey, Anamika; Pandi-Perumal, Seithikurippu R.; Stoian, Anca Mihaela Pantea; Pardhan, Shahina; Parekh, Tarang; Parekh, Utsav; Pasovic, Maja; Patel, Jay; Patel, Jenil R.; Paudel, Uttam; Pepito, Veincent Christian Filipino; Pereira, Marcos; Perico, Norberto; Perna, Simone; Petcu, Ionela-Roxana; Petermann-Rocha, Fanny Emily; Podder, Vivek; Postma, Maarten J.; Pourali, Ghazaleh; Pourtaheri, Naeimeh; Prates, Elton Junio Sady; Qadir, Mirza Muhammad Fahd; Qattea, Ibrahim; Raee, Pourya; Rafique, Ibrar; Rahimi, Mehran; Rahimifard, Mahban; Rahimi-Movaghar, Vafa; Rahman, Md Obaidur; Rahman, Muhammad Aziz; Rahman, Mohammad Hifz Ur; Rahman, Mosiur; Rahman, Md Mosfequr; Rahmani, Mohamed; Rahmani, Shayan; Rahmanian, Vahid; Rahmawaty, Setyaningrum; Rahnavard, Niloufar; Rajbhandari, Bibek; Ram, Pradhum; Ramazanu, Sheena; Rana, Juwel; Rancic, Nemanja; Ranjha, Muhammad Modassar Ali Nawaz; Rao, Chythra R.; Rapaka, Deepthi; Rasali, Drona Prakash; Rashedi, Sina; Rashedi, Vahid; Rashid, Ahmed Mustafa; Rashidi, Mohammad-Mahdi; Ratan, Zubair Ahmed; Rawaf, Salman; Rawal, Lal; Redwan, Elrashdy Moustafa Mohamed; Remuzzi, Giuseppe; Rengasamy, Kannan R. R.; Renzaho, Andre M. N.; Reyes, Luis Felipe; Rezaei, Nima; Rezaei, Nazila; Rezaeian, Mohsen; Rezazadeh, Hossein; Riahi, Seyed Mohammad; Rias, Yohanes Andy; Riaz, Muhammad; Ribeiro, Daniela; Rodrigues, Monica; Rodriguez, Jefferson Antonio Buendia; Roever, Leonardo; Rohloff, Peter; Roshandel, Gholamreza; Roustazadeh, Abazar; Rwegerera, Godfrey M.; Saad, Aly M. A.; Saber-Ayad, Maha Mohamed; Sabour, Siamak; Sabzmakan, Leila; Saddik, Basema; Sadeghi, Erfan; Saeed, Umar; Moghaddam, Sahar Saeedi; Safi, Sare; Safi, Sher Zaman; Saghazadeh, Amene; Sharif-Askari, Narjes Saheb; Sharif-Askari, Fatemeh Saheb; Sahebkar, Amirhossein; Sahoo, Soumya Swaroop; Sahoo, Harihar; Saif-Ur-Rahman, K.M.; Sajid, Mirza Rizwan; Salahi, Sarvenaz; Salahi, Saina; Saleh, Mohamed A.; Salehi, Mohammad Amin; Salomon, Joshua A.; Sanabria, Juan; Sanjeev, Rama Krishna; Sanmarchi, Francesco; Santric-Milicevic, Milena M.; Sarasmita, Made Ary; Sargazi, Saman; Sathian, Brijesh; Sathish, Thirunavukkarasu; Sawhney, Monika; Schlaich, Markus P.; Schmidt, Maria Ines; Schuermans, Art; Seidu, Abdul-Aziz; Kumar, Nachimuthu Senthil; Sepanlou, Sadaf G.; Sethi, Yashendra; Seylani, Allen; Shabany, Maryam; Shafaghat, Tahereh; Shafeghat, Melika; Shafie, Mahan; Shah, Nilay S.; Shahid, Samiah; Shaikh, Masood Ali; Shanawaz, Mohd; Shannawaz, Mohammed; Sharfaei, Sadaf; Shashamo, Bereket Beyene; Shiri, Rahman; Shittu, Aminu; Shivakumar, K.M.; Shivalli, Siddharudha; Shobeiri, Parnian; Shokri, Fereshteh; Shuval, Kerem; Sibhat, Migbar Mekonnen; Silva, Luis Manuel Lopes Rodrigues; Simpson, Colin R.; Singh, Jasvinder A.; Singh, Paramdeep; Singh, Surjit; Siraj, Md Shahjahan; Skryabina, Anna Aleksandrovna; Sohag, Abdullah Al Mamun; Soleimani, Hamidreza; Solikhah, Solikhah; Soltani-Zangbar, Mohammad Sadegh; Somayaji, Ranjani; Sorensen, Reed J. D.; Starodubova, Antonina V.; Sujata, Sujata; Suleman, Muhammad; Sun, Jing; Sundstr�m, Johan; Tabar�s-Seisdedos, Rafael; Tabatabaei, Seyyed Mohammad; Tabatabaeizadeh, Seyed-Amir; Tabish, Mohammad; Taheri, Majid; Taheri, Ensiyeh; Taki, Elahe; Tamuzi, Jacques J. L. Lukenze; Tan, Ker-Kan; Tat, Nathan Y.; Taye, Birhan Tsegaw; Temesgen, Worku Animaw; Temsah, Mohamad-Hani; Tesler, Riki; Thangaraju, Pugazhenthan; Thankappan, Kavumpurathu Raman; Thapa, Rajshree; Tharwat, Samar; Thomas, Nihal; Ticoalu, Jansje Henny Vera; Tiyuri, Amir; Tonelli, Marcello; Tovani-Palone, Marcos Roberto; Trico, Domenico; Trihandini, Indang; Tripathy, Jaya Prasad; Tromans, Samuel Joseph; Tsegay, Guesh Mebrahtom; Tualeka, Abdul Rohim; Tufa, Derara Girma; Tyrovolas, Stefanos; Ullah, Sana; Upadhyay, Era; Vahabi, Seyed Mohammad; Vaithinathan, Asokan Govindaraj; Valizadeh, Rohollah; van Daalen, Kim Robin; Vart, Priya; Varthya, Shoban Babu; Vasankari, Tommi Juhani; Vaziri, Siavash; Verma, Madhur Verma; Verras, Georgios-Ioannis; Vo, Danh Cao; Wagaye, Birhanu; Waheed, Yasir; Wang, Ziyue; Wang, Yanqing; Wang, Cong; Wang, Fang; Wassie, Gizachew Tadesse; Wei, Melissa Y. Wei; Weldemariam, Abrha Hailay; Westerman, Ronny; Wickramasinghe, Nuwan Darshana; Wu, YiFan; Wulandari, Ratna D. W. I.; Xia, Juan; Xiao, Hong; Xu, Suowen; Xu, Xiaoyue; Yada, Dereje Y.; Yang, Lin; Yatsuya, Hiroshi; Yesiltepe, Metin; Yi, Siyan; Yohannis, Hunachew Kibret; Yonemoto, Naohiro; You, Yuyi; Zaman, Sojib Bin; Zamora, Nelson; Zare, Iman; Zarea, Kourosh; Zarrintan, Armin; Zastrozhin, Mikhail Sergeevich; Zeru, Naod Gebrekrstos; Zhang, Zhi-Jiang; Zhong, Chenwen; Zhou, Jingjing; Zieli?ska, Magdalena; Zikarg, Yossef Teshome; Zodpey, Sanjay; Zoladl, Mohammad; Zou, Zhiyong; Zumla, Alimuddin; Zuniga, Yves Miel H.; Magliano, Dianna J.; Murray, Christopher J. L.; Hay, Simon I.; Vos, TheoBackground: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims; type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative risk assessment framework to estimate the risk-attributable type 2 diabetes burden for 16 risk factors falling under risk categories including environmental and occupational factors, tobacco use, high alcohol use, high body-mass index (BMI), dietary factors, and low physical activity. Using a regression framework, we forecast type 1 and type 2 diabetes prevalence through 2050 with Socio-demographic Index (SDI) and high BMI as predictors, respectively. Findings: In 2021, there were 529 million (95% uncertainty interval [UI] 500�564) people living with diabetes worldwide, and the global age-standardised total diabetes prevalence was 6�1% (5�8�6�5). At the super-region level, the highest age-standardised rates were observed in north Africa and the Middle East (9�3% [8�7�9�9]) and, at the regional level, in Oceania (12�3% [11�5�13�0]). Nationally, Qatar had the world's highest age-specific prevalence of diabetes, at 76�1% (73�1�79�5) in individuals aged 75�79 years. Total diabetes prevalence�especially among older adults�primarily reflects type 2 diabetes, which in 2021 accounted for 96�0% (95�1�96�8) of diabetes cases and 95�4% (94�9�95�9) of diabetes DALYs worldwide. In 2021, 52�2% (25�5�71�8) of global type 2 diabetes DALYs were attributable to high BMI. The contribution of high BMI to type 2 diabetes DALYs rose by 24�3% (18�5�30�4) worldwide between 1990 and 2021. By 2050, more than 1�31 billion (1�22�1�39) people are projected to have diabetes, with expected age-standardised total diabetes prevalence rates greater than 10% in two super-regions: 16�8% (16�1�17�6) in north Africa and the Middle East and 11�3% (10�8�11�9) in Latin America and Caribbean. By 2050, 89 (43�6%) of 204 countries and territories will have an age-standardised rate greater than 10%. Interpretation: Diabetes remains a substantial public health issue. Type 2 diabetes, which makes up the bulk of diabetes cases, is largely preventable and, in some cases, potentially reversible if identified and managed early in the disease course. However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. Preventing and controlling type 2 diabetes remains an ongoing challenge. It is essential to better understand disparities in risk factor profiles and diabetes burden across populations, to inform strategies to successfully control diabetes risk factors within the context of multiple and complex drivers. Funding: Bill & Melinda Gates Foundation. � 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseItem Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990�2019: results from the Global Burden of Disease Study 2019(Elsevier Ltd, 2021-09-23T00:00:00) Ledesma, Jorge R.; Ma, Jianing; Vongpradith, Avina; Maddison, Emilie R.; Novotney, Amanda; Biehl, Molly H.; Legrand, Kate E.; Ross, Jennifer M.; Jahagirdar, Deepa; Bryazka, Dana; Feldman, Rachel; Abolhassani, Hassan; Abosetugn, Akine Eshete; Abu-Gharbieh, Eman; Adebayo, Oladimeji M.; Adnani, Qorinah Estiningtyas Sakilah; Afzal, Saira; Ahinkorah, Bright Opoku; Ahmad, Sajjad Ahmad; Ahmadi, Sepideh; Rashid, Tarik Ahmed; Salih, Yusra Ahmed; Aklilu, Addis; Akunna, Chisom Joyqueenet; Al Hamad, Hanadi; Alahdab, Fares; Alemayehu, Yosef; Alene, Kefyalew Addis; Ali, Beriwan Abdulqadir; Ali, Liaqat; Alipour, Vahid; Alizade, Hesam; Al-Raddadi, Rajaa M.; Alvis-Guzman, Nelson; Amini, Saeed; Amit, Arianna Maever L.; Anderson, Jason A.; Androudi, Sofa; Antonio, Carl Abelardo T.; Antony, Catherine M.; Anwer, Razique; Arabloo, Jalal; Arja, Asrat; Asemahagn, Mulusew A.; Atre, Sachin R.; Azhar, Gulrez Shah; Darshan, B.B.; Babar, Zaheer-Ud-Din; Baig, Atif Amin; Banach, Maciej; Barqawi, Hiba Jawdat; Barra, Fabio; Barrow, Amadou; Basu, Sanjay; Belgaumi, Uzma Iqbal; Bhagavathula, Akshaya Srikanth; Bhardwaj, Nikha; Bhardwaj, Pankaj; Bhattacharjee, Natalia V.; Bhattacharyya, Krittika; Bijani, Ali; Bikbov, Boris; Boloor, Archith; Briko, Nikolay Ivanovich; Buonsenso, Danilo; Nagaraja, Sharath Burugina; Butt, Zahid A.; Carter, Austin; Carvalho, Felix; Charan, Jaykaran; Chatterjee, Souranshu; Chattu, Soosanna Kumary; Chattu, Vijay Kumar; Christopher, Devasahayam J.; Chu, Dinh-Toi; Claassens, Mareli M.; Dadras, Omid; Dagnew, Amare Belachew; Dai, Xiaochen; Dandona, Lalit; Dandona, Rakhi; Daneshpajouhnejad, Parnaz; Darwesh, Aso Mohammad; Dhamnetiya, Deepak; Dianatinasab, Mostafa; Diaz, Daniel; Doan, Linh Phuong; Eftekharzadeh, Sahar; Elhadi, Muhammed; Emami, Amir; Enany, Shymaa; Faraon, Emerito Jose A.; Farzadfar, Farshad; Fernandes, Eduarda; Desideri, Lorenzo Ferro; Filip, Irina; Fischer, Florian; Foroutan, Masoud; Frank, Tahvi D.; Garcia-Basteiro, Alberto L.; Garcia-Calavaro, Christian; Garg, Tushar; Geberemariyam, Biniyam Sahiledengle; Ghadiri, Keyghobad; Ghashghaee, Ahmad; Golechha, Mahaveer; Goodridge, Amador; Gupta, Bhawna; Gupta, Sapna; Gupta, Veer Bala; Gupta, Vivek Kumar; Haider, Mohammad Rifat; Hamidi, Samer; Hanif, Asif; Haque, Shaful; Harapan, Harapan; Hargono, Arief; Hasaballah, Ahmed I.; Hashi, Abdiwahab; Hassan, Shoaib; Hassankhani, Hadi; Hayat, Khezar; Hezam, Kamal; Holla, Ramesh; Hosseinzadeh, Mehdi; Hostiuc, Mihaela; Househ, Mowafa; Hussain, Rabia; Ibitoye, Segun Emmanuel; Ilic, Irena M.; Ilic, Milena D.; Irvani, Seyed Sina Naghibi; Ismail, Nahlah Elkudssiah; Itumalla, Ramaiah; Jaafari, Jalil; Jacobsen, Kathryn H.; Jain, Vardhmaan; Javanmardi, Fatemeh; Jayapal, Sathish Kumar; Jayaram, Shubha; Jha, Ravi Prakash; Jonas, Jost B.; Joseph, Nitin; Joukar, Farahnaz; Kabir, Zubair; Kamath, Ashwin; Kanchan, Tanuj; Kandel, Himal; Katoto, Patrick D.M.C.; Kayode, Gbenga A.; Kendrick, Parkes J.; Kerbo, Amene Abebe; Khajuria, Himanshu; Khalilov, Rovshan; Khatab, Khaled; Khoja, Abdullah T.; Khubchandani, Jagdish; Kim, Min Seo; Kim, Yun Jin; Kisa, Adnan; Kisa, Sezer; Kosen, Soewarta; Koul, Parvaiz A.; Laxminarayana, Sindhura Lakshmi Koulmane; Koyanagi, Ai; Krishan, Kewal; Bicer, Burcu Kucuk; Kumar, Avinash; Kumar, G. Anil; Kumar, Narinder; Kumar, Nithin; Kwarteng, Alexander; Lak, Hassan Mehmood; Lal, Dharmesh Kumar; Landires, Iv�n; Lasrado, Savita; Lee, Shaun Wen Huey; Lee, Wei-Chen; Lin, Christine; Liu, Xuefeng; Lopukhov, Platon D.; Lozano, Rafael; Machado, Daiane Borges; Kunjathur, Shilpashree Madhava; Madi, Deepak; Mahajan, Preetam Bhalchandra; Majeed, Azeem; Malik, Ahmad Azam; Martins-Melo, Francisco Rogerl�ndio; Mehta, Saurabh; Memish, Ziad A.; Mendoza, Walter; Menezes, Ritesh G.; Merie, Hayimro Edemealem; Mersha, Amanual Getnet; Mesregah, Mohamed Kamal; Mestrovic, Tomislav; Mheidly, Nour Mheidly; Misra, Sanjeev; Mithra, Prasanna; Moghadaszadeh, Masoud; Mohammadi, Mokhtar; Mohammadian-Hafshejani, Abdollah; Mohammed, Shafu; Molokhia, Mariam; Moni, Mohammad Ali; Al Montasir, Ahmed; Moore, Catrin E.; Nagarajan, Ahamarshan Jayaraman; Nair, Sanjeev; Nair, Suma; Naqvi, Atta Abbas; Swamy, Sreenivas Narasimha; Nayak, Biswa Prakash; Nazari, Javad; Kandel, Sandhya Neupane; Nguyen, Trang Huyen; Nixon, Molly R.; Nnaji, Chukwudi A.; Ntsekhe, Mpiko; Nu�ez-Samudio, Virginia; Oancea, Bogdan; Odukoya, Oluwakemi Ololade; Olagunju, Andrew T.; Oren, Eyal; Mahesh, P.A.; Parthasarathi, Ramakrishnan; Kan, Fatemeh Pashazadeh; Pattanshetty, Sanjay M.; Paudel, Rajan; Paul, Pintu; Pawar, Shrikant; Pepito, Veincent Christian Filipino; Perico, Norberto; Pirestani, Majid; Polibin, Roman V.; Postma, Maarten J.; Pourshams, Akram; Prashant, Akila; Pribadi, Dimas Ria Angga; Radfar, Amir; Rafei, Alireza; Rahim, Fakher; Rahimi-Movaghar, Vafa; Rahman, Mahfuzar; Rahman, Mosiur; Rahmani, Amir Masoud; Ranasinghe, Priyanga; Rao, Chythra R.; Rawaf, David Laith; Rawaf, Salman; Reitsma, Marissa B.; Remuzzi, Giuseppe; Renzaho, Andre M. N.; Reta, Melese Abate; Rezaei, Nima; Rezahosseini, Omid; Rezai, Mohammad Sadegh; Rezapour, Aziz; Roshandel, Gholamreza; Roshchin, Denis O.; Sabour, Siamak; Saif-Ur-rahman, K.M.; Salam, Nasir; Kafl, Hossein Samadi; Samaei, Mehrnoosh; Samy, Abdallah M.; Saroshe, Satish; Sartorius, Benn; Sathian, Brijesh; Sawyer, Susan M.; Senthilkumaran, Subramanian; Seylani, Allen; Shafaat, Omid; Shaikh, Masood Ali; Sharaf, Kiomars; Shetty, Ranjitha S.; Shigematsu, Mika; Shin, Jae Il; Silva, Jo�o Pedro; Singh, Jitendra Kumar; Sinha, Smriti; Skryabin, Valentin Yurievich; Skryabina, Anna Aleksandrovna; Spurlock, Emma Elizabeth; Sreeramareddy, Chandrashekhar T.; Steiropoulos, Paschalis; Sufyan, Mu'awiyyah Babale; Tabuchi, Takahiro; Tadesse, Eyayou Girma; Tamir, Zemenu; Tarkang, Elvis Enowbeyang; Tekalegn, Yohannes; Tesfay, Fisaha Haile; Tessema, Belay; Thapar, Rekha; Tleyjeh, Imad I.; Tobe-Gai, Ruoyan; Tran, Bach Xuan; Tsegaye, Berhan; Tsegaye, Gebiyaw Wudie; Ullah, Anayat; Umeokonkwo, Chukwuma David; Tahbaz, Sahel Valadan; Vo, Bay; Vu, Giang Thu; Waheed, Yasir; Walters, Magdalene K.; Whisnant, Joanna L.; Woldekidan, Mesfn Agachew; Wubishet, Befkadu Legesse; Jabbari, Seyed Hossein Yahyazadeh; Yazie, Taklo Simeneh Yazie; Yeshaw, Yigizie; Yi, Siyan; Yigit, Vahit; Yonemoto, Naohiro; Yu, Chuanhua; Yunusa, Ismaeel; Zastrozhin, Mikhail Sergeevich; Zastrozhina, Anasthasia; Zhang, Zhi-Jiang; Zumla, Alimuddin; Mokdad, Ali H.; Salomon, Joshua A.; Reiner, Robert C.; Lim, Stephen S.; Naghavi, Mohsen; Vos, Theo; Hay, Simon I.; Murray, Christopher J. L.; Kyu, Hmwe HmweBackground: Tuberculosis is a major contributor to the global burden of disease, causing more than a million deaths annually. Given an emphasis on equity in access to diagnosis and treatment of tuberculosis in global health targets, evaluations of differences in tuberculosis burden by sex are crucial. We aimed to assess the levels and trends of the global burden of tuberculosis, with an emphasis on investigating differences in sex by HIV status for 204 countries and territories from 1990 to 2019. Methods: We used a Bayesian hierarchical Cause of Death Ensemble model (CODEm) platform to analyse 21 505 site-years of vital registration data, 705 site-years of verbal autopsy data, 825 site-years of sample-based vital registration data, and 680 site-years of mortality surveillance data to estimate mortality due to tuberculosis among HIV-negative individuals. We used a population attributable fraction approach to estimate mortality related to HIV and tuberculosis coinfection. A compartmental meta-regression tool (DisMod-MR 2.1) was then used to synthesise all available data sources, including prevalence surveys, annual case notifications, population-based tuberculin surveys, and tuberculosis cause-specific mortality, to produce estimates of incidence, prevalence, and mortality that were internally consistent. We further estimated the fraction of tuberculosis mortality that is attributable to independent effects of risk factors, including smoking, alcohol use, and diabetes, for HIV-negative individuals. For individuals with HIV and tuberculosis coinfection, we assessed mortality attributable to HIV risk factors including unsafe sex, intimate partner violence (only estimated among females), and injection drug use. We present 95% uncertainty intervals for all estimates. Findings: Globally, in 2019, among HIV-negative individuals, there were 1�18 million (95% uncertainty interval 1�08�1�29) deaths due to tuberculosis and 8�50 million (7�45�9�73) incident cases of tuberculosis. Among HIV-positive individuals, there were 217 000 (153 000�279 000) deaths due to tuberculosis and 1�15 million (1�01�1�32) incident cases in 2019. More deaths and incident cases occurred in males than in females among HIV-negative individuals globally in 2019, with 342 000 (234 000�425 000) more deaths and 1�01 million (0�82�1�23) more incident cases in males than in females. Among HIV-positive individuals, 6250 (1820�11 400) more deaths and 81 100 (63 300�100 000) more incident cases occurred among females than among males in 2019. Age-standardised mortality rates among HIV-negative males were more than two times greater in 105 countries and age-standardised incidence rates were more than 1�5 times greater in 74 countries than among HIV-negative females in 2019. The fraction of global tuberculosis deaths among HIV-negative individuals attributable to alcohol use, smoking, and diabetes was 4�27 (3�69�5�02), 6�17 (5�48�7�02), and 1�17 (1�07�1�28) times higher, respectively, among males than among females in 2019. Among individuals with HIV and tuberculosis coinfection, the fraction of mortality attributable to injection drug use was 2�23 (2�03�2�44) times greater among males than females, whereas the fraction due to unsafe sex was 1�06 (1�05�1�08) times greater among females than males. Interpretation: As countries refine national tuberculosis programmes and strategies to end the tuberculosis epidemic, the excess burden experienced by males is important. Interventions are needed to actively communicate, especially to men, the importance of early diagnosis and treatment. These interventions should occur in parallel with efforts to minimise excess HIV burden among women in the highest HIV burden countries that are contributing to excess HIV and tuberculosis coinfection burden for females. Placing a focus on tuberculosis burden among HIV-negative males and HIV and tuberculosis coinfection among females might help to diminish the overall burden of tuberculosis. This strategy will be crucial in reaching both equity and burden targets outlined by global health milestones. Funding: Bill & Melinda Gates Foundation. � 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseItem Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990�2019: results from the Global Burden of Disease Study 2019(Elsevier Ltd, 2021-09-23T00:00:00) Ledesma, Jorge R.; Ma, Jianing; Vongpradith, Avina; Maddison, Emilie R.; Novotney, Amanda; Biehl, Molly H.; Legrand, Kate E.; Ross, Jennifer M.; Jahagirdar, Deepa; Bryazka, Dana; Feldman, Rachel; Abolhassani, Hassan; Abosetugn, Akine Eshete; Abu-Gharbieh, Eman; Adebayo, Oladimeji M.; Adnani, Qorinah Estiningtyas Sakilah; Afzal, Saira; Ahinkorah, Bright Opoku; Ahmad, Sajjad Ahmad; Ahmadi, Sepideh; Rashid, Tarik Ahmed; Salih, Yusra Ahmed; Aklilu, Addis; Akunna, Chisom Joyqueenet; Al Hamad, Hanadi; Alahdab, Fares; Alemayehu, Yosef; Alene, Kefyalew Addis; Ali, Beriwan Abdulqadir; Ali, Liaqat; Alipour, Vahid; Alizade, Hesam; Al-Raddadi, Rajaa M.; Alvis-Guzman, Nelson; Amini, Saeed; Amit, Arianna Maever L.; Anderson, Jason A.; Androudi, Sofa; Antonio, Carl Abelardo T.; Antony, Catherine M.; Anwer, Razique; Arabloo, Jalal; Arja, Asrat; Asemahagn, Mulusew A.; Atre, Sachin R.; Azhar, Gulrez Shah; Darshan, B.B.; Babar, Zaheer-Ud-Din; Baig, Atif Amin; Banach, Maciej; Barqawi, Hiba Jawdat; Barra, Fabio; Barrow, Amadou; Basu, Sanjay; Belgaumi, Uzma Iqbal; Bhagavathula, Akshaya Srikanth; Bhardwaj, Nikha; Bhardwaj, Pankaj; Bhattacharjee, Natalia V.; Bhattacharyya, Krittika; Bijani, Ali; Bikbov, Boris; Boloor, Archith; Briko, Nikolay Ivanovich; Buonsenso, Danilo; Nagaraja, Sharath Burugina; Butt, Zahid A.; Carter, Austin; Carvalho, Felix; Charan, Jaykaran; Chatterjee, Souranshu; Chattu, Soosanna Kumary; Chattu, Vijay Kumar; Christopher, Devasahayam J.; Chu, Dinh-Toi; Claassens, Mareli M.; Dadras, Omid; Dagnew, Amare Belachew; Dai, Xiaochen; Dandona, Lalit; Dandona, Rakhi; Daneshpajouhnejad, Parnaz; Darwesh, Aso Mohammad; Dhamnetiya, Deepak; Dianatinasab, Mostafa; Diaz, Daniel; Doan, Linh Phuong; Eftekharzadeh, Sahar; Elhadi, Muhammed; Emami, Amir; Enany, Shymaa; Faraon, Emerito Jose A.; Farzadfar, Farshad; Fernandes, Eduarda; Desideri, Lorenzo Ferro; Filip, Irina; Fischer, Florian; Foroutan, Masoud; Frank, Tahvi D.; Garcia-Basteiro, Alberto L.; Garcia-Calavaro, Christian; Garg, Tushar; Geberemariyam, Biniyam Sahiledengle; Ghadiri, Keyghobad; Ghashghaee, Ahmad; Golechha, Mahaveer; Goodridge, Amador; Gupta, Bhawna; Gupta, Sapna; Gupta, Veer Bala; Gupta, Vivek Kumar; Haider, Mohammad Rifat; Hamidi, Samer; Hanif, Asif; Haque, Shaful; Harapan, Harapan; Hargono, Arief; Hasaballah, Ahmed I.; Hashi, Abdiwahab; Hassan, Shoaib; Hassankhani, Hadi; Hayat, Khezar; Hezam, Kamal; Holla, Ramesh; Hosseinzadeh, Mehdi; Hostiuc, Mihaela; Househ, Mowafa; Hussain, Rabia; Ibitoye, Segun Emmanuel; Ilic, Irena M.; Ilic, Milena D.; Irvani, Seyed Sina Naghibi; Ismail, Nahlah Elkudssiah; Itumalla, Ramaiah; Jaafari, Jalil; Jacobsen, Kathryn H.; Jain, Vardhmaan; Javanmardi, Fatemeh; Jayapal, Sathish Kumar; Jayaram, Shubha; Jha, Ravi Prakash; Jonas, Jost B.; Joseph, Nitin; Joukar, Farahnaz; Kabir, Zubair; Kamath, Ashwin; Kanchan, Tanuj; Kandel, Himal; Katoto, Patrick D.M.C.; Kayode, Gbenga A.; Kendrick, Parkes J.; Kerbo, Amene Abebe; Khajuria, Himanshu; Khalilov, Rovshan; Khatab, Khaled; Khoja, Abdullah T.; Khubchandani, Jagdish; Kim, Min Seo; Kim, Yun Jin; Kisa, Adnan; Kisa, Sezer; Kosen, Soewarta; Koul, Parvaiz A.; Laxminarayana, Sindhura Lakshmi Koulmane; Koyanagi, Ai; Krishan, Kewal; Bicer, Burcu Kucuk; Kumar, Avinash; Kumar, G. Anil; Kumar, Narinder; Kumar, Nithin; Kwarteng, Alexander; Lak, Hassan Mehmood; Lal, Dharmesh Kumar; Landires, Iv�n; Lasrado, Savita; Lee, Shaun Wen Huey; Lee, Wei-Chen; Lin, Christine; Liu, Xuefeng; Lopukhov, Platon D.; Lozano, Rafael; Machado, Daiane Borges; Kunjathur, Shilpashree Madhava; Madi, Deepak; Mahajan, Preetam Bhalchandra; Majeed, Azeem; Malik, Ahmad Azam; Martins-Melo, Francisco Rogerl�ndio; Mehta, Saurabh; Memish, Ziad A.; Mendoza, Walter; Menezes, Ritesh G.; Merie, Hayimro Edemealem; Mersha, Amanual Getnet; Mesregah, Mohamed Kamal; Mestrovic, Tomislav; Mheidly, Nour Mheidly; Misra, Sanjeev; Mithra, Prasanna; Moghadaszadeh, Masoud; Mohammadi, Mokhtar; Mohammadian-Hafshejani, Abdollah; Mohammed, Shafu; Molokhia, Mariam; Moni, Mohammad Ali; Al Montasir, Ahmed; Moore, Catrin E.; Nagarajan, Ahamarshan Jayaraman; Nair, Sanjeev; Nair, Suma; Naqvi, Atta Abbas; Swamy, Sreenivas Narasimha; Nayak, Biswa Prakash; Nazari, Javad; Kandel, Sandhya Neupane; Nguyen, Trang Huyen; Nixon, Molly R.; Nnaji, Chukwudi A.; Ntsekhe, Mpiko; Nu�ez-Samudio, Virginia; Oancea, Bogdan; Odukoya, Oluwakemi Ololade; Olagunju, Andrew T.; Oren, Eyal; Mahesh, P.A.; Parthasarathi, Ramakrishnan; Kan, Fatemeh Pashazadeh; Pattanshetty, Sanjay M.; Paudel, Rajan; Paul, Pintu; Pawar, Shrikant; Pepito, Veincent Christian Filipino; Perico, Norberto; Pirestani, Majid; Polibin, Roman V.; Postma, Maarten J.; Pourshams, Akram; Prashant, Akila; Pribadi, Dimas Ria Angga; Radfar, Amir; Rafei, Alireza; Rahim, Fakher; Rahimi-Movaghar, Vafa; Rahman, Mahfuzar; Rahman, Mosiur; Rahmani, Amir Masoud; Ranasinghe, Priyanga; Rao, Chythra R.; Rawaf, David Laith; Rawaf, Salman; Reitsma, Marissa B.; Remuzzi, Giuseppe; Renzaho, Andre M. N.; Reta, Melese Abate; Rezaei, Nima; Rezahosseini, Omid; Rezai, Mohammad Sadegh; Rezapour, Aziz; Roshandel, Gholamreza; Roshchin, Denis O.; Sabour, Siamak; Saif-Ur-rahman, K.M.; Salam, Nasir; Kafl, Hossein Samadi; Samaei, Mehrnoosh; Samy, Abdallah M.; Saroshe, Satish; Sartorius, Benn; Sathian, Brijesh; Sawyer, Susan M.; Senthilkumaran, Subramanian; Seylani, Allen; Shafaat, Omid; Shaikh, Masood Ali; Sharaf, Kiomars; Shetty, Ranjitha S.; Shigematsu, Mika; Shin, Jae Il; Silva, Jo�o Pedro; Singh, Jitendra Kumar; Sinha, Smriti; Skryabin, Valentin Yurievich; Skryabina, Anna Aleksandrovna; Spurlock, Emma Elizabeth; Sreeramareddy, Chandrashekhar T.; Steiropoulos, Paschalis; Sufyan, Mu'awiyyah Babale; Tabuchi, Takahiro; Tadesse, Eyayou Girma; Tamir, Zemenu; Tarkang, Elvis Enowbeyang; Tekalegn, Yohannes; Tesfay, Fisaha Haile; Tessema, Belay; Thapar, Rekha; Tleyjeh, Imad I.; Tobe-Gai, Ruoyan; Tran, Bach Xuan; Tsegaye, Berhan; Tsegaye, Gebiyaw Wudie; Ullah, Anayat; Umeokonkwo, Chukwuma David; Tahbaz, Sahel Valadan; Vo, Bay; Vu, Giang Thu; Waheed, Yasir; Walters, Magdalene K.; Whisnant, Joanna L.; Woldekidan, Mesfn Agachew; Wubishet, Befkadu Legesse; Jabbari, Seyed Hossein Yahyazadeh; Yazie, Taklo Simeneh Yazie; Yeshaw, Yigizie; Yi, Siyan; Yigit, Vahit; Yonemoto, Naohiro; Yu, Chuanhua; Yunusa, Ismaeel; Zastrozhin, Mikhail Sergeevich; Zastrozhina, Anasthasia; Zhang, Zhi-Jiang; Zumla, Alimuddin; Mokdad, Ali H.; Salomon, Joshua A.; Reiner, Robert C.; Lim, Stephen S.; Naghavi, Mohsen; Vos, Theo; Hay, Simon I.; Murray, Christopher J. L.; Kyu, Hmwe HmweBackground: Tuberculosis is a major contributor to the global burden of disease, causing more than a million deaths annually. Given an emphasis on equity in access to diagnosis and treatment of tuberculosis in global health targets, evaluations of differences in tuberculosis burden by sex are crucial. We aimed to assess the levels and trends of the global burden of tuberculosis, with an emphasis on investigating differences in sex by HIV status for 204 countries and territories from 1990 to 2019. Methods: We used a Bayesian hierarchical Cause of Death Ensemble model (CODEm) platform to analyse 21 505 site-years of vital registration data, 705 site-years of verbal autopsy data, 825 site-years of sample-based vital registration data, and 680 site-years of mortality surveillance data to estimate mortality due to tuberculosis among HIV-negative individuals. We used a population attributable fraction approach to estimate mortality related to HIV and tuberculosis coinfection. A compartmental meta-regression tool (DisMod-MR 2.1) was then used to synthesise all available data sources, including prevalence surveys, annual case notifications, population-based tuberculin surveys, and tuberculosis cause-specific mortality, to produce estimates of incidence, prevalence, and mortality that were internally consistent. We further estimated the fraction of tuberculosis mortality that is attributable to independent effects of risk factors, including smoking, alcohol use, and diabetes, for HIV-negative individuals. For individuals with HIV and tuberculosis coinfection, we assessed mortality attributable to HIV risk factors including unsafe sex, intimate partner violence (only estimated among females), and injection drug use. We present 95% uncertainty intervals for all estimates. Findings: Globally, in 2019, among HIV-negative individuals, there were 1�18 million (95% uncertainty interval 1�08�1�29) deaths due to tuberculosis and 8�50 million (7�45�9�73) incident cases of tuberculosis. Among HIV-positive individuals, there were 217 000 (153 000�279 000) deaths due to tuberculosis and 1�15 million (1�01�1�32) incident cases in 2019. More deaths and incident cases occurred in males than in females among HIV-negative individuals globally in 2019, with 342 000 (234 000�425 000) more deaths and 1�01 million (0�82�1�23) more incident cases in males than in females. Among HIV-positive individuals, 6250 (1820�11 400) more deaths and 81 100 (63 300�100 000) more incident cases occurred among females than among males in 2019. Age-standardised mortality rates among HIV-negative males were more than two times greater in 105 countries and age-standardised incidence rates were more than 1�5 times greater in 74 countries than among HIV-negative females in 2019. The fraction of global tuberculosis deaths among HIV-negative individuals attributable to alcohol use, smoking, and diabetes was 4�27 (3�69�5�02), 6�17 (5�48�7�02), and 1�17 (1�07�1�28) times higher, respectively, among males than among females in 2019. Among individuals with HIV and tuberculosis coinfection, the fraction of mortality attributable to injection drug use was 2�23 (2�03�2�44) times greater among males than females, whereas the fraction due to unsafe sex was 1�06 (1�05�1�08) times greater among females than males. Interpretation: As countries refine national tuberculosis programmes and strategies to end the tuberculosis epidemic, the excess burden experienced by males is important. Interventions are needed to actively communicate, especially to men, the importance of early diagnosis and treatment. These interventions should occur in parallel with efforts to minimise excess HIV burden among women in the highest HIV burden countries that are contributing to excess HIV and tuberculosis coinfection burden for females. Placing a focus on tuberculosis burden among HIV-negative males and HIV and tuberculosis coinfection among females might help to diminish the overall burden of tuberculosis. This strategy will be crucial in reaching both equity and burden targets outlined by global health milestones. Funding: Bill & Melinda Gates Foundation. � 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseItem Higher education as a bridge between china and nepal: Mapping education as soft power in chinese foreign policy(MDPI AG, 2021-07-15T00:00:00) Gauttam, Priya; Singh, Bawa; Chattu, Vijay KumarIn this globalized world, education has become an important medium to enhance people-to-people contact. The Delores report of the International Commission on Education for the 21st century highlights the enormous potential of higher education to use globalization as a resource for bridging the knowledge gap and enriching cross-cultural dialogue. As a major contributor to soft power and an important field of public diplomacy, international education can have a wealth of advantages, including the ability to generate commercial value, promote a country�s foreign policy goals and interests, and contribute to economic growth and investment. The People�s Republic of China, well-known for being the world�s most populous nation and the global economic powerhouse, prioritizes the internationalization of the country�s higher education system. China is looking to expand its higher education program and carry out its diplomatic project in South Asia. In this sense, the South Asian zone, especially Nepal, is significant for China, where its educational diplomacy is playing as a �bridge between Sino-Nepal relations.� In this review, we describe the place and priority of �Education� in China�s foreign policy; explore China�s mediums of investment in Nepal�s education sector; and highlight the importance of educational aid in Sino-Nepal relations. Chinese educational aid to Nepal takes many forms, where Nepali students and officials engage with Chinese investment to enhance their career prospects and the education system in Nepal. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.Item India�s Health Diplomacy as a Soft Power Tool towards Africa: Humanitarian and Geopolitical Analysis(SAGE Publications Ltd, 2021-09-17T00:00:00) Mol, Rajani; Singh, Bawa; Chattu, Vijay Kumar; Kaur, Jaspal; Singh, BalinderIndia and Africa have been sharing a multidimensional relationship of cooperation and friendship since the ancient civilizations. The COVID-19 pandemic has brought new possibilities and opportunities for India to leverage its soft power diplomacy towards Africa. The paper�s main focus is to analyze how India has made soft power part of its foreign policy and examine India�s relationship with the African continent through health diplomacy. A literature search was done in major databases, such as Web of Science, Medicine/PubMed, Scopus, OVID, and Google Scholar search engine to gather relevant information. Through humanitarian assistance and geopolitical influence, India had won the support and heart of Africans. Besides, India has become a global healthcare provider in the African continent through its global health diplomacy and vaccine diplomacy. India has achieved impressive gains through its soft power diplomacy and has become a compassionate and benevolent actor in the African continent. � The Author(s) 2021.Item India�s Neighbourhood Vaccine Diplomacy During COVID-19 Pandemic: Humanitarian and Geopolitical Perspectives(SAGE Publications Ltd, 2022-02-18T00:00:00) Singh, Bawa; Singh, Sandeep; Singh, Balinder; Chattu, Vijay KumarIn recent years, India has established itself as the world�s �pharmacy hub�, and this claim was proven once again when it delivered COVID-19 vaccines to its citizens, neighbouring nations and across the globe. Following the philosophy of humanitarianism through the principle of �Vasudhaiva Kutumbakam�, India has decided to provide the COVID-19 health assistance to its immediate neighbouring countries. India�s immediate neighbourhood refers to the countries that are geographically adjacent to it. In addition, India�s vaccine diplomacy has exposed geopolitical fault lines in South Asia as China�s vaccine diplomacy aims to outpace India in the region. Against this background, the main objective of this paper is to explain and examine India�s vaccine diplomacy as an instrument of its �Neighbourhood First� policy during the COVID-19 pandemic. It argues that India�s health-focused approach has proved effective and aligned with its national interests. This review demonstrates that India�s health diplomacy has had an impact on medical and humanitarian assistance reciprocation at the regional and international levels. As a result of this strategy, during the second wave of the pandemic, India received medical devices and vaccines from other countries in dealing with COVID-19. � The Author(s) 2022.Item Measuring routine childhood vaccination coverage in 204 countries and territories, 1980�2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1(Elsevier B.V., 2021-07-21T00:00:00) Galles, Natalie C; Liu, Patrick Y; Updike, Rachel L; Fullman, Nancy; Nguyen, Jason; Rolfe, Sam; Sbarra, Alyssa N; Schipp, Megan F; Marks, Ashley; Abady, Gdiom Gebreheat; Abbas, Kaja M; Abbasi, Sumra Wajid; Abbastabar, Hedayat; Abd-Allah, Foad; Abdoli, Amir; Abolhassani, Hassan; Abosetugn, Akine Eshete; Adabi, Maryam; Adamu, Abdu A; Adetokunboh, Olatunji O; Adnani, Qorinah Estiningtyas Sakilah; Advani, Shailesh M; Afzal, Saira; Aghamir, Seyed Mohammad Kazem; Ahinkorah, Bright Opoku; Ahmad, Sohail; Ahmad, Tauseef; Ahmadi, Sepideh; Ahmed, Haroon; Ahmed, Muktar Beshir; Ahmed Rashid, Tarik; Ahmed Salih, Yusra; Akalu, Yonas; Aklilu, Addis; Akunna, Chisom Joyqueenet; Al Hamad, Hanadi; Alahdab, Fares; Albano, Luciana; Alemayehu, Yosef; Alene, Kefyalew Addis; Al-Eyadhy, Ayman; Alhassan, Robert Kaba; Ali, Liaqat; Aljunid, Syed Mohamed; Almustanyir, Sami; Altirkawi, Khalid A; Alvis-Guzman, Nelson; Amu, Hubert; Andrei, Catalina Liliana; Andrei, Tudorel; Ansar, Adnan; Ansari-Moghaddam, Alireza; Antonazzo, Ippazio Cosimo; Antony, Benny; Arabloo, Jalal; Arab-Zozani, Morteza; Artanti, Kurnia Dwi; Arulappan, Judie; Awan, Asma Tahir; Awoke, Mamaru Ayenew; Ayza, Muluken Altaye; Azarian, Ghasem; Azzam, Ahmed Y; B, Darshan B; Babar, Zaheer-Ud-Din; Balakrishnan, Senthilkumar; Banach, Maciej; Bante, Simachew Animen; B�rnighausen, Till Winfried; Barqawi, Hiba Jawdat; Barrow, Amadou; Bassat, Quique; Bayarmagnai, Narantuya; Bejarano Ramirez, Diana Fernanda; Bekuma, Tariku Tesfaye; Belay, Habtamu Gebrehana; Belgaumi, Uzma Iqbal; Bhagavathula, Akshaya Srikanth; Bhandari, Dinesh; Bhardwaj, Nikha; Bhardwaj, Pankaj; Bhaskar, Sonu; Bhattacharyya, Krittika; Bibi, Sadia; Bijani, Ali; Biondi, Antonio; Boloor, Archith; Braithwaite, Dejana; Buonsenso, Danilo; Butt, Zahid A; Camargos, Paulo; Carreras, Giulia; Carvalho, Felix; Casta�eda-Orjuela, Carlos A; Chakinala, Raja Chandra; Charan, Jaykaran; Chatterjee, Souranshu; Chattu, Soosanna Kumary; Chattu, Vijay Kumar; Chowdhury, Fazle Rabbi; Christopher, Devasahayam J; Chu, Dinh-Toi; Chung, Sheng-Chia; Cortesi, Paolo Angelo; Costa, Vera Marisa; Couto, Rosa A S; Dadras, Omid; Dagnew, Amare Belachew; Dagnew, Baye; Dai, Xiaochen; Dandona, Lalit; Dandona, Rakhi; De Neve, Jan-Walter; Derbew Molla, Meseret; Derseh, Behailu Tariku; Desai, Rupak; Desta, Abebaw Alemayehu; Dhamnetiya, Deepak; Dhimal, Mandira Lamichhane; Dhimal, Meghnath; Dianatinasab, Mostafa; Diaz, Daniel; Djalalinia, Shirin; Dorostkar, Fariba; Edem, Bassey; Edinur, Hisham Atan; Eftekharzadeh, Sahar; El Sayed, Iman; El Sayed Zaki, Maysaa; Elhadi, Muhammed; El-Jaafary, Shaimaa I; Elsharkawy, Aisha; Enany, Shymaa; Erkhembayar, Ryenchindorj; Esezobor, Christopher Imokhuede; Eskandarieh, Sharareh; Ezeonwumelu, Ifeanyi Jude; Ezzikouri, Sayeh; Fares, Jawad; Faris, Pawan Sirwan; Feleke, Berhanu Elfu; Ferede, Tomas Y; Fernandes, Eduarda; Fernandes, Jo�o C; Ferrara, Pietro; Filip, Irina; Fischer, Florian; Francis, Mark Rohit; Fukumoto, Takeshi; Gad, Mohamed M; Gaidhane, Shilpa; Gallus, Silvano; Garg, Tushar; Geberemariyam, Biniyam Sahiledengle; Gebre, Teshome; Gebregiorgis, Birhan Gebresillassie; Gebremedhin, Ketema Bizuwork; Gebremichael, Berhe; Gessner, Bradford D; Ghadiri, Keyghobad; Ghafourifard, Mansour; Ghashghaee, Ahmad; Gilani, Syed Amir; Gl?van, Ionela-Roxana; Glushkova, Ekaterina Vladimirovna; Golechha, Mahaveer; Gonfa, Kebebe Bekele; Gopalani, Sameer Vali; Goudarzi, Houman; Gubari, Mohammed Ibrahim Mohialdeen; Guo, Yuming; Gupta, Veer Bala; Gupta, Vivek Kumar; Guti�rrez, Reyna Alma; Haeuser, Emily; Halwani, Rabih; Hamidi, Samer; Hanif, Asif; Haque, Shafiul; Harapan, Harapan; Hargono, Arief; Hashi, Abdiwahab; Hassan, Shoaib; Hassanein, Mohamed H; Hassanipour, Soheil; Hassankhani, Hadi; Hay, Simon I; Hayat, Khezar; Hegazy, Mohamed I; Heidari, Golnaz; Hezam, Kamal; Holla, Ramesh; Hoque, Mohammad Enamul; Hosseini, Mostafa; Hosseinzadeh, Mehdi; Hostiuc, Mihaela; Househ, Mowafa; Hsieh, Vivian Chia-rong; Huang, Junjie; Humayun, Ayesha; Hussain, Rabia; Hussein, Nawfal R; Ibitoye, Segun Emmanuel; Ilesanmi, Olayinka Stephen; Ilic, Irena M; Ilic, Milena D; Inamdar, Sumant; Iqbal, Usman; Irham, Lalu Muhammad; Irvani, Seyed Sina Naghibi; Islam, Sheikh Mohammed Shariful; Ismail, Nahlah Elkudssiah; Itumalla, Ramaiah; Jha, Ravi Prakash; Joukar, Farahnaz; Kabir, Ali; Kabir, Zubair; Kalhor, Rohollah; Kamal, Zul; Kamande, Stanley M; Kandel, Himal; Karch, Andr�; Kassahun, Getinet; Kassebaum, Nicholas J; Katoto, Patrick DMC; Kelkay, Bayew; Kengne, Andre Pascal; Khader, Yousef Saleh; Khajuria, Himanshu; Khalil, Ibrahim A; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khan, Junaid; Khan, Maseer Adnan; Khan, Moien AB; Khang, Young-Ho; Khoja, Abdullah T; Khubchandani, Jagdish; Kim, Gyu Ri; Kim, Min Seo; Kim, Yun Jin; Kimokoti, Ruth W; Kisa, Adnan; Kisa, Sezer; Korshunov, Vladimir Andreevich; Kosen, Soewarta; Kuate Defo, Barthelemy; Kulkarni, Vaman; Kumar, Avinash; Kumar, G Anil; Kumar, Nithin; Kwarteng, Alexander; La Vecchia, Carlo; Lami, Faris Hasan; Landires, Iv�n; Lasrado, Savita; Lassi, Zohra S; Lee, Hankil; Lee, Yeong Yeh; Levi, Miriam; Lewycka, Sonia; Li, Shanshan; Liu, Xuefeng; Lobo, Stany W; Lopukhov, Platon D; Lozano, Rafael; Lutzky Saute, Ricardo; Magdy Abd El Razek, Muhammed; Makki, Alaa; Malik, Ahmad Azam; Mansour-Ghanaei, Fariborz; Mansournia, Mohammad Ali; Mantovani, Lorenzo Giovanni; Martins-Melo, Francisco Rogerl�ndio; Matthews, Philippa C; Medina, John Robert Carabeo; Mendoza, Walter; Menezes, Ritesh G; Mengesha, Endalkachew Worku; Meretoja, Tuomo J; Mersha, Amanual Getnet; Mesregah, Mohamed Kamal; Mestrovic, Tomislav; Miazgowski, Bartosz; Milne, George J; Mirica, Andreea; Mirrakhimov, Erkin M; Mirzaei, Hamid Reza; Misra, Sanjeev; Mithra, Prasanna; Moghadaszadeh, Masoud; Mohamed, Teroj Abdulrahman; Mohammad, Karzan Abdulmuhsin; Mohammad, Yousef; Mohammadi, Mokhtar; Mohammadian-Hafshejani, Abdollah; Mohammed, Arif; Mohammed, Shafiu; Mohapatra, Archisman; Mokdad, Ali H; Molokhia, Mariam; Monasta, Lorenzo; Moni, Mohammad Ali; Montasir, Ahmed Al; Moore, Catrin E; Moradi, Ghobad; Moradzadeh, Rahmatollah; Moraga, Paula; Mueller, Ulrich Otto; Munro, Sandra B; Naghavi, Mohsen; Naimzada, Mukhammad David; Naveed, Muhammad; Nayak, Biswa Prakash; Negoi, Ionut; Neupane Kandel, Sandhya; Nguyen, Trang Huyen; Nikbakhsh, Rajan; Ningrum, Dina Nur Anggraini; Nixon, Molly R; Nnaji, Chukwudi A; Noubiap, Jean Jacques; Nu�ez-Samudio, Virginia; Nwatah, Vincent Ebuka; Oancea, Bogdan; Ochir, Chimedsuren; Ogbo, Felix Akpojene; Olagunju, Andrew T; Olakunde, Babayemi Oluwaseun; Onwujekwe, Obinna E; Otstavnov, Nikita; Otstavnov, Stanislav S; Owolabi, Mayowa O; Padubidri, Jagadish Rao; Pakshir, Keyvan; Park, Eun-Cheol; Pashazadeh Kan, Fatemeh; Pathak, Mona; Paudel, Rajan; Pawar, Shrikant; Pereira, Jeevan; Peres, Mario F P; Perianayagam, Arokiasamy; Pinheiro, Marina; Pirestani, Majid; Podder, Vivek; Polibin, Roman V; Pollok, Richard Charles G; Postma, Maarten J; Pottoo, Faheem Hyder; Rabiee, Mohammad; Rabiee, Navid; Radfar, Amir; Rafiei, Alireza; Rahimi-Movaghar, Vafa; Rahman, Mosiur; Rahmani, Amir Masoud; Rahmawaty, Setyaningrum; Rajesh, Aashish; Ramshaw, Rebecca E; Ranasinghe, Priyanga; Rao, Chythra R; Rao, Sowmya J; Rathi, Priya; Rawaf, David Laith; Rawaf, Salman; Renzaho, Andre M N; Rezaei, Negar; Rezai, Mohammad Sadegh; Rios-Blancas, Maria; Rogowski, Emma L B; Ronfani, Luca; Rwegerera, Godfrey M; Saad, Anas M; Sabour, Siamak; Saddik, Basema; Saeb, Mohammad Reza; Saeed, Umar; Sahebkar, Amirhossein; Sahraian, Mohammad Ali; Salam, Nasir; Salimzadeh, Hamideh; Samaei, Mehrnoosh; Samy, Abdallah M; Sanabria, Juan; Sanmarchi, Francesco; Santric-Milicevic, Milena M; Sartorius, Benn; Sarveazad, Arash; Sathian, Brijesh; 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Filip, I.; Filip, I.; Fischer, F.; Francis, M.R.; Francis, M.R.; Fukumoto, T.; Gad, M.M.; Hassanein, M.H.; Liu, X.; Saad, A.M.; Gad, M.M.; Garg, T.; Tekalegn, Y.; Mohammed, S.; Gebre, T.; Gebremedhin, K.B.; Gessner, B.D.; Gessner, B.D.; Ghadiri, K.; Ghadiri, K.; Ghafourifard, M.; Moghadaszadeh, M.; Gilani, S.; Malik, A.A.; Gilani, S.; Glushkova, E.V.; Korshunov, V.A.; Lopukhov, P.D.; Golechha, M.; Gopalani, S.V.; Gopalani, S.V.; Goudarzi, H.; Ahmed, M.B.; Goudarzi, H.; Gubari, M.I.M.; Guo, Y.; Li, S.; Guo, Y.; Gupta, V.; Gupta, V.K.; Guti�rrez, R.A.; Hargono Dr, A.; Hassan, S.; Hassan, S.; Hassanipour, S.; Hayat, K.; Hayat, K.; Heidari, G.; Islam, S.; Hsieh, V.; Huang, J.; Zhong, C.; Humayun, A.; Hussain, R.; Hussein, N.R.; Ibitoye, S.E.; Ilesanmi, O.S.; Makki, A.; Noubiap, J.; Santric-Milicevic, M.M.; Santric-Milicevic, M.M.; Inamdar, S.; Iqbal, U.; Irham, L.M.; Ningrum, D.N.A.; Irvani, S.N.; Islam, S.; Kalhor, R.; Kalhor, R.; Kamal, Z.; Kamal, Z.; Karch, A.; Katoto, P.D.; Nnaji, C.A.; Khan, J.; Khoja, A.T.; Khubchandani, J.; Khoja, A.T.; Kim, G.; Kim, M.; Kim, M.; Kim, Y.; Kimokoti, R.W.; Kosen, S.; Kumar, A.; Kwarteng, A.; La Vecchia, C.; Landires, I.; Nu�ez-Samudio, V.; Nu�ez-Samudio, V.; Landires, I.; Lasrado, S.; Levi, M.; Levi, M.; Matthews, P.C.; Moore, C.E.; Liu, X.; Sanabria, J.; Lobo, S.W.; Lobo, S.W.; Malik, A.A.; Mantovani, L.G.; Matthews, P.C.; Medina, J.C.; Medina, J.C.; Mendoza, W.; Menezes, R.G.; Meretoja, T.J.; Meretoja, T.J.; Meretoja, T.J.; Mersha, A.G.; Mesregah, M.K.; Mestrovic, T.; Mestrovic, T.; Milne, G.J.; Mohammad, K.A.; Mohammadi, M.; Mohammed, A.; Mohammed, S.; Mohapatra, A.; Molokhia, M.; Traini, E.; Moradi, G.; Mirzaei, H.; Zamanian, M.; Moraga, P.; Mueller, U.O.; Mueller, U.O.; Munro, S.B.; Naimzada, M.; Naveed, M.; Negoi, I.; Nguyen, T.H.; Vu, L.G.; Nguyen, T.H.; Vu, L.G.; Ningrum, D.N.A.; Ogbo, F.A.; Olagunju, A.T.; Olakunde, B.O.; Onwujekwe, O.E.; Pathak, M.; Pawar, S.; Pereira, J.; Peres, M.F.P.; Peres, M.F.P.; Pirestani, M.; Pollok, R.C.G.; Postma, M.J.; Postma, M.J.; Rabiee, M.; Rezai, M.; Rahman, M.; Rahmawaty, S.; Rajesh, A.; Ranasinghe, P.; Rawaf, D.L.; Rawaf, S.; Rawaf, D.L.; Rawaf, S.; Rwegerera, G.M.; Saeb, M.; Saeed, U.; Saeed, U.; Salam, N.; Samaei, M.; Sanabria, J.; Sanmarchi, F.; Sathian, B.; Sawhney, M.; Seidu, A.; Seidu, A.; Shaikh, M.A.; Shigematsu, M.; Soheili, A.; Tan, K.; Thakur, B.; Traini, E.; Tripathi, M.; Ullah, S.; Ullah, S.; Vo, B.; Vu, G.T.; Winkler, A.S.; Winkler, A.S.; Yu, C.; Yuce, D.Background: Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. Methods: For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. Findings: By 2019, global coverage of third-dose DTP (DTP3; 81�6% [95% uncertainty interval 80�4�82�7]) more than doubled from levels estimated in 1980 (39�9% [37�5�42�1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38�5% [35�4�41�3] in 1980 to 83�6% [82�3�84�8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42�6% (41�4�44�1) in 1980 to 79�8% (78�4�81�1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56�8 million (52�6�60�9) to 14�5 million (13�4�15�9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. Interpretation: After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines. Funding: Bill & Melinda Gates Foundation. � 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseItem Prioritizing 'equity' in COVID-19 vaccine distribution through Global Health Diplomacy(Tabriz University of Medical Sciences, 2021-09-30T00:00:00) Singh, Bawa; Chattu, Vijay KumarWith over 4 million deaths worldwide, the current coronavirus disease 2019 (COVID-19) pandemic is regarded as one of the worst pandemics in history. With its wider devastating consequences, even so-called affluent countries could not provide full coverage for COVID-19 vaccines and medications to all of their citizens. Against this backdrop, the main aim of this article is to examine how Global Health Diplomacy (GHD) can play a role in prioritizing vaccine equity in the global health agenda in the fight against COVID-19. The majority of developed countries' healthcare systems have been exposed and have reached a tipping point. After the completion of eighteen months of the pandemic, only five countries were able to produce vaccines for the treatment of COVID-19. This pandemic has divided the world into two blocs: those with vaccines, such as the United States, the United Kingdom, Russia, China, and India; and those without, such as the rest of the world. The greatest challenges are vaccine inequalities, inequities and distribution, which undermine the global economic recovery. Many poor countries are still waiting for the initial doses to be delivered to their citizens, while some rich nations are planning for booster doses. GHD plays a critical role in establishing successful global collaborations, funding mechanisms and ensuring international cooperation through the combined efforts of all stakeholders. Besides, global solidarity is necessary to lessen the wider gaps between the vaccination status of rich and poor nations. Therefore, through GHD, the vaccine gaps and inequities can be addressed to strengthen global health security and accelerate global economic recovery. � 2021 The Author(s).Item Public health policy of India and COVID-19: Diagnosis and prognosis of the combating response(MDPI AG, 2021-03-22T00:00:00) Gauttam, Priya; Patel, Nitesh; Singh, Bawa; Kaur, Jaspal; Chattu, Vijay Kumar; Jakovljevic, Mihajlo(1) Background: Society and public policy have been remained interwoven since the inception of the modern state. Public health policy has been one of the important elements of the public administration of the Government of India (GOI). In order to universalize healthcare facilities for all, the GOI has formulated and implemented the national health policy (NHP). The latest NHP (2017) has been focused on the �Health in All� approach. On the other hand, the ongoing pandemic COVID-19 had left critical impacts on India�s health, healthcare system, and human security. The paper�s main focus is to critically examine the existing healthcare facilities and the GOI�s response to combat the COVID-19 apropos the NHP 2017. The paper suggests policy options that can be adopted to prevent the further expansion of the pandemic and prepare the country for future health emergency-like situations. (2) Methods: Extensive literature search was done in various databases, such as Scopus, Web of Science, Medline/PubMed, and google scholar search engines to gather relevant information in the Indian context. (3) Results: Notwithstanding the several combatting steps on a war-footing level, COVID-19 has placed an extra burden over the already overstretched healthcare infrastructure. Consequently, infected cases and deaths have been growing exponentially, making India stand in second place among the top ten COVID-19-infected countries. (4) Conclusions: India needs to expand the public healthcare system and enhance the expenditure as per the set goals in NHP-17 and WHO standards. The private healthcare system has not been proved reliable during the emergency. Only the public health system is suitable for the country wherein the population�s substantial size is rural and poor. � 2021 by the authors. Licensee MDPI, Basel, Switzerland.