Browsing by Author "Chauhan, Gaurav"

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    Distribution of neotectonic variability between the Kachchh Mainland Fault and Vigodi Fault, Northwestern Mainland Kachchh, Western India
    (Elsevier Ltd, 2022-01-13T00:00:00) Kothyari, Girish Ch; Mishra, Sneha; Taloor, Ajay Kumar; Kandregula, Raj Sunil; Pathak, Vamdev; Chauhan, Gaurav
    As per the Bureau of Indian Standards (BIS), the Kachchh region of the western peninsular India falls under seismically active region, where the faults experienced existence of several moderate to high magnitude earthquakes in the historic past. The present-day seismicity is mainly concentrated toward the eastern part of Kachchh Mainland Fault (KMF). Even though, the western segment of the KMF does not exhibit seismicity at present, but the tectono-geomorphology of this segment reveals various active geomorphic features which indicates its active nature. In this study, we are focusing on the distribution of neotectonic variability between the western segment of the KMF and the Vigodi Fault (VF), as the detailed geomorphometric studies is lacking in this region, believing that the area is not promising for such studies because the lack of seismicity. Therefore, we applied the conventional morphometric parameters to assess the neotectonic behaviour of the study area. The computed morphometric parameters had been grouped and mixed to create the Relative Index of Active Tectonics (RIAT), Furthermore, we used DInSAR results to estimate the active vertical displacement in between the fault zones which ranges from 0.15 to 0.28 cm. The results of each geomorphic indices indicates active deformation within the central portion of the western KMF and VF zone. This study would be certainly beneficial for seismic hazard assessment and future infrastructure planning of the region. � 2022 The Authors
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    Is highly expressed ACE 2 in pregnant women �a curse� in times of COVID-19 pandemic?
    (Elsevier Inc., 2020-10-28T00:00:00) Dhaundiyal, Ankit; Kumari, Puja; Jawalekar, Snehal Sainath; Chauhan, Gaurav; Kalra, Sourav; Navik, Umashanker
    Angiotensin-converting enzyme 2 (ACE 2) is a membrane-bound enzyme that cleaves angiotensin II (Ang II) into angiotensin (1�7). It also serves as an important binding site for SARS-CoV-2, thereby, facilitating viral entry into target host cells. ACE 2 is abundantly present in the intestine, kidney, heart, lungs, and fetal tissues. Fetal ACE 2 is involved in myocardium growth, lungs and brain development. ACE 2 is highly expressed in pregnant women to compensate preeclampsia by modulating angiotensin (1�7) which binds to the Mas receptor, having vasodilator action and maintain fluid homeostasis. There are reports available on Zika, H1N1 and SARS-CoV where these viruses have shown to produce fetal defects but very little is known about SARS-CoV-2 involvement in pregnancy, but it might have the potential to interact with fetal ACE 2 and enhance COVID-19 transmission to the fetus, leading to fetal morbidity and mortality. This review sheds light on a path of SARS-CoV-2 transmission risk in pregnancy and its possible link with fetal ACE 2. � 2020 Elsevier Inc.