Browsing by Author "Kumar, Sandeep"

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Advanced membrane technology for the removal of pesticides from water and wastewater
(Elsevier, 2022-05-21T00:00:00) Yadav, Sangita; Chauhan, Amit Kumar; Kumar, Sandeep; Kataria, Navish
Agricultural runoff is one of the main factors that introduces pesticide residue into water. Common pesticides such as DEET(N,N-diethyl-meta-toluamide), DDT(dichloro diphenyl trichloroethane), metolachlor, malathion, etc., have continuously contaminated water systems. These pesticides are toxic and can cause detrimental effects on living organisms, even at trace amounts. Most pesticides are grouped into chemical families and persist the environment for long periods. Therefore, specific water treatment is required to clean the waterbodies contaminated with pesticides. Several conventional treatment methods have been introduced in the past to decontaminate the waterbodies. However, there are many advantages and disadvantages associated with these processes. Nowadays, membrane technology is one of the best and preferred method available to treat contaminated water because of its high efficiency, cost effectiveness, easy applicability, stability, and low footprint. Membrane filtration includes reverse osmosis, nanofiltration, ultrafiltration, nanofiber filtration, and biomembrane filtration processes for pollution separation. Membrane materials and filtration processes can be modified depending on the chemical structure and properties of the pesticides. Recent advances in nanotechnology offer energy-efficient, low cost, and eco-friendly approaches in water treatment technologies. Membrane materials can be modified to obtain better results and increase its effectiveness for treatment process. Recently, researchers have started working to introduce new nanomaterials including carbon nanotubes, nanopolymers, metal-organic nanomembrane, graphene, quantum and nanoshells development of membrane filters for water purification. Recently, membrane materials progress has allowed filtration to become more effective over other conventional treatment methods and popularized globally. � 2022 Elsevier Inc. All rights reserved.
EFFECT OF DIFFERENT JAB TECHNIQUES ON PEAK ACTIVATION OF UPPER-BODY MUSCLES IN YOUTH BOXERS
(OVS LLC, 2022-12-23T00:00:00) Kumar, Sandeep; Ramirez-Campillo, Rodrigo; Singh, Joseph; Kumar, Sanjeev; Gogoi, Hemantajit
The study purpose was to analyse the peak EMG at five upper-body muscles during four different jab techniques in youth boxers. Materials and methods. Male youth national-level boxers (n=7) were assessed for peak electromyography (EMG) of anterior deltoid (AD), biceps brachii (BB), triceps brachii (TB), flexor carpi radialis (FCR), and upper trapezius (UT) while performing four jab techniques: long-range targeting head (LRH), long-range targeting body (LRB), medium-range targeting head (MRH), and medium-range targeting body (MRB). Results. The LRH induced the highest EMG for AD (2092.9�411.9) and BB (1392.0�687.3). The MRB induced the highest EMG for the FCR (1337.16�538.28), TB (1589.3�600.3), and UT (1221.2�507.5). However, between jab techniques, only the AD showed a significant (p<0.001) different EMG. Specifically, the LRH induced greater AD EMG compared to LRB (157.5 [p<0.001]), MRH (411.0 [p=0.003]), and MRB (398.3 [p=0.010]). Further, the LRB induced greater AD EMG compared to MRH (253.5 [p=0.024]) and MRB (240.8 [p=0.049]). The MRH and MRB (-12.7 [p=0.911]) induced similar AD EMG. Conclusions. Peak EMG at five upper-body muscles varies between jab techniques. However, the differences seem relatively small, except for the AD muscle, with a descending pattern of peak EMG for the LRH > LRB > MRH and MRB jab techniques. � Kumar, S., Ramirez-Campillo, R., Singh, J., Kumar, S., & Gogoi, H., 2022.
Effect of imidazolium based ionic liquids on CO-association dynamics and thermodynamic stability of Ferrocytochrome c
(Elsevier B.V., 2020-11-05T00:00:00) Garg, Mansi; Kumar, Sandeep; Kaur, Anupamjeet; Goyal, Bhupesh; Kumar, Rajesh
Analysis of kinetic and thermodynamic parameters measured for CO-association reaction of Ferrocytochrome c (Ferrocyt c) under variable concentrations of 1-butyl-3-methylimidazolium with varying anion ([Bmim]X) (X = Cl?, I?, Br?, HSO4?) at pH 7 revealed that the low concentration of [Bmim]X (?0.5 M) constrains the CO-association dynamics of Ferrocyt c and typically follows the order: [Bmim]HSO4 > [Bmim]Cl > [Bmim]Br > [Bmim]I. At relatively higher concentrations (>0.5), the chaotropic action of [Bmim]+ dominates which consequently increases the thermal-fluctuations responsible to denature the protein and thus accelerates the speed of CO-association reaction. Analysis of thermal denaturation curves of Ferrocyt c measured at different concentrations of [Bmim]X revealed that the [Bmim]X decreases the thermodynamic stability of protein and typically follows the order: [Bmim]I > [Bmim]Br > [Bmim]Cl > [Bmim]CH3COO > [Bmim]HSO4, demonstrating that the effect of [Bmim]X on thermodynamic stability of protein is not in accordance to Hofmeister series effect of anions because instead of increasing the kosmotropic anion carrying [Bmim]X ([Bmim]CH3COO and [Bmim]HSO4) also decreases the thermodynamic stability of protein. � 2020 Elsevier B.V.
Evaluation of synergistic adsorption approach for terbinafine removal by cotton shell powder immobilized zerovalent copper: Adsorption kinetics and DFT simulation
(Elsevier B.V., 2023-08-30T00:00:00) Kaur, Parminder; Hussain, Khadim; Kumar, Atul; Singh, Janpreet; Nagendra Babu, J.; Kumar, Sandeep
Cotton shell powder (CS), nano zerovalent copper (nZVC) and cotton shell powder immobilized zerovalent copper (ZVC@CS) were evaluated for their adsorption efficiencies towards terbinafine hydrochloride (TBH), an antifungal drug. The nZVC and ZVC@CS synthesized via one pot redox precipitation method were characterized by FTIR, XRD, BET, FESEM and TGA analysis. The TGA and AAS analysis confirmed the loading of nearly 10% of nZVC on cotton shell powder in ZVC@CS. The effect of operational parameters (pH, adsorbent dose, initial drug concentration, time, etc.) determining the extent of terbinafine hydrochloride adsorption on ZVC@CS were investigated to ascertain the optimal experimental conditions to achieve maximum adsorption efficiencies. To investigate the adsorption behavior of TBH on ZVC@CS, the experimental data were fitted for five different adsorption models viz. Langmuir, Freundlich, Temkin, Redlich-Peterson and Hill isotherms. The TBH adsorption data was best fit with Hill isotherm model indicating cooperative sorption of TBH molecules on ZVC@CS surface. Among the five kinetic equations namely the pseudo-first-order (PFO), the pseudo-second-order (PSO), Elovich model, the intraparticle diffusion model, and Boyd kinetic model used to estimate the adsorption mechanism, the PFO kinetic model give best fit with a good correlation for the physisorption of TBH on ZVC@CS composite. The mechanism of the adsorption process was observed to be complex, consisting of both surface adsorption and pore diffusion. However, the Boyd plot confirms external mass transport as the rate limiting step for the adsorption of TBH on ZVC@CS. The synergistic adsorption of TBH on ZVC@CS was hypothesized, and the idea was supported by structure optimization results from DFT studies. The ZVC@CS exhibits equilibrium TBH adsorption efficiency (qmax) of 285.3 mg.g?1, significantly higher than adsorbents used in literature for the TBH removal. It is suggested that ZVC@CS may serve as sustainable adsorbents for the removal of cationic contaminants from acidic medium. � 2023 Elsevier B.V.
Fabrication of energy storage EDLC device based on self-synthesized TiO2 nanowire dispersed polymer nanocomposite films
(Springer Science and Business Media Deutschland GmbH, 2021-05-24T00:00:00) Devi, Chandni; Swaroop, Ram; Arya, Anil; Tanwar, Shweta; Sharma, A.L.; Kumar, Sandeep
In this work, a systematic study of titanium oxide (TiO2) nanowires incorporated polymer nanocomposite (PNC) films prepared by a standard solution cast technique is reported. The structural, morphological, dielectric, and electrochemical properties were investigated thoroughly. The polymer nanocomposite films demonstrated improved electrical and electrochemical properties as compared to polymer�salt complex film. The morphological and structural properties have been examined by the field emission scanning electron microscope, Fourier transform infrared spectroscopy, and X-ray diffraction. It is observed that the maximum ionic conductivity is of the order of 10�5 S cm?1 exhibited by 0.5 wt% nanowire added polymer nanocomposite film. The ion transference number was close to unity for optimized film and stability window of about ~ 5�V. The shift of loss tangent peak toward the high-frequency window with nanowire addition indicates a decrease of the relaxation time. The optimized TiO2 nanowire dispersed polymer nanocomposite film has been used to fabricate the electric double-layer capacitor cells. The fabricated cell demonstrates the specific capacitance of about 57.5 F/g (at 10�mV/s). The calculated energy density and power density are 1.38 Wh kg?1 and 0.709�kW�kg?1, respectively. The Coulombic efficiency is 97.7% up to the 500 cycles for the fabricated cell. The prepared polymer nanocomposite has the potential to use it as electrolyte cum separator for solid-state electric double-layer capacitor applications. � 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Methods to Detect Nitric Oxide and Reactive Nitrogen Species in Biological Sample
(Humana Press Inc., 2022-01-19T00:00:00) Kaur, Sharanjot; Gupta, Kunj Bihari; Kumar, Sandeep; Upadhyay, Shishir; Mantha, Anil Kumar; Dhiman, Monisha
Oxidative stress has been implicated in various human diseases, including cancer, mainly through the generation of reactive nitrogen species (RNS), such as nitric oxide (NO), nitrite, nitroxyl, s-nitrosothiols, and reactive oxygen species (ROS) such as peroxides, superoxide, and hydroxyl radicals. NO being the main player among RNS induced altered cellular molecules and metabolisms, thus making it important to understand and detect the generation of NO in biological samples. There are many methods for direct and indirect detection of NO; out of these most commonly used are spectrophotometric-based Griess assay and fluorescence probe-based assays. In this chapter, we summarize these routinely used methods to detect NO and various challenges associated with these methods. � 2022, Springer Science+Business Media, LLC, part of Springer Nature.
Nanoscale zerovalent copper (nZVC) catalyzed environmental remediation of organic and inorganic contaminants: A review
(Elsevier Ltd, 2022-08-08T00:00:00) Kumar, Sandeep; Kaur, Parminder; Brar, Ravinderdeep Singh; Babu, J Nagendra
Over the past decade, the nano zerovalent copper has emerged as an effective nano-catalyst for the environment remediation processes due to its ease of synthesis, low cost, controllable particle size and high reactivity despite its release during the remediation process and related concentration dependent toxicities. However, the improvised techniques involving the use of supports or immobilizer for the synthesis of Cu0 has significantly increased its stability and motivated the researchers to explore the applicability of Cu0 for the environment remediation processes, which is evident from access to numerous reports on nano zerovalent copper mediated remediation of contaminants. Initially, this review allows the understanding of the various resources used to synthesize zerovalent copper nanomaterial and the structure of Cu0 nanoparticles, followed by focus on the reaction mechanism and the species involved in the contaminant remediation process. The studies comprehensively presented the application of nano zerovalent copper for remediation of organic/inorganic contaminants in combination with various oxidizing and reducing agents under oxic and anoxic conditions. Further, it was evaluated that the immobilizers or support combined with various irradiation sources originates a synergistic effect and have a significant effect on the stability and the redox properties of nZVC in the remediation process. Therefore, the review proposed that the future scope of research should include rigorous focus on deriving an exact mechanism for synergistic effect for the removal of contaminants by supported nZVC. � 2022 The Author(s)
Nanoscale zerovalent iron (nZVI): An efficient heterogeneous catalyst for environment remediation
(De Gruyter, 2022-05-09T00:00:00) Kumar, Sandeep; Brar, Ravinderdeep Singh; Nagendra Babu, J.; Hussain, Khadim
[No abstract available]
Poverty in Multidimensional Perspective: Policy Insights from Selected North Indian Districts
(SAGE Publications Ltd, 2020-11-21T00:00:00) Mishra, P.K.; Kumar, Sandeep; Arif, Mohd.; Niyazi, Atta-Ula; Kaur, Kiranpreet
This article examined the multidimensional aspects of poverty in selected North Indian districts using the Alkire�Foster counting method of estimating poverty incidence and intensity. Whereas more than half of the sample households are found to be vulnerable to poverty, about a quarter of households are observed to be in the grip of poverty in these districts. Among the dimensions of deprivations, education, standard of living and economic and social security are critical in contributing to multidimensional poverty and vulnerability. In these dimensions, people are mostly deprived of fuel for cooking, sanitation, ownership assets, informal jobs and social security measures. Therefore, the policymakers ought to be proactive in understanding the socio-economic structure of these districts to formulate inclusive distributive policies as appropriate area wise. However, policies such as urbanization, promotion of technical/vocational education, initiation of micro and small entrepreneurial activities completing and supplementing to farm activities and introducing measures of social protection can help people come out of the tragedies of poverty. � 2022 Association of Asia Scholars.
Recent Advancement in Nanotechnology for the Treatment of Pharmaceutical Wastewater: Sources, Toxicity, and Remediation Technology
(Springer Science and Business Media Deutschland GmbH, 2023-03-11T00:00:00) Kumar, Sandeep; Yadav, Sangita; Kataria, Navish; Chauhan, Amit Kumar; Joshi, Seema; Gupta, Renuka; Kumar, Parmod; Chong, Jun Wei Roy; Khoo, Kuan Shiong; Show, Pau Loke
The textile, paper and pulp, distillery, and pharmaceutical industries are only a few of the many sectors that contribute significantly to the contamination of water bodies and their unsuitability for human use. Pharmaceuticals, which are credited with saving millions of lives in recent decades, have emerged as a new category of environmental hazard. Their prolonged presence in the environment has a number of negative effects, including gene toxicity, hormone interference, antibiotic resistance, the imposition of sex organs, and many others. To ensure that everyone in the world can access to uncontaminated and safe drinking water, it is important to treat pharmaceutical laden wastewater before discharge in fresh water body. Nanotechnology is getting significant attention due to enormous properties such as the high surface area to volume ratio, new optical properties, and desired shape. Nanomaterials might be a strong option for purifying water of a variety of environmental pollutants. This review also touches on several environmental aspects of pharmaceuticals, including (i) the current status of pharmaceuticals production and their use pattern, (ii) sources, occurrence, and transport behaviour of pharmaceuticals, (iii) analysis techniques and potential toxicity of pharmaceuticals and (iv) various conventional and advanced nanotechnology for water remediation. The present review is predominately designed to highlight the progress and major update in advantaged nanotechnology for remediation of pharmaceutical contaminated wastewater. The literature study (2015�2022) critically illustrated the recent pharmaceutical contaminations concerns and remediation efforts emphasizing nanotechnology like nanoadsorption, AOPs, nano-catalyst, electrochemical degradation and nanomembrane/nanofiltration technology. � 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Role of Macromolecular Crowding on Stability and Iron Release Kinetics of Serum Transferrin
(American Chemical Society, 2017) Kumar, Sandeep; Sharma, Deepak; Kumar, Rajesh
The macromolecular crowding influences the structural stability and functional properties of transferrin (Tf). The equilibrium as well as kinetic studies of Tf at different concentrations of crowding agents (dextran 40, dextran 70, and ficoll 70) and at a fixed concentration of dextran 40 under different concentrations of NaCl at pH 7.4 and 5.6 (?1) revealed that (i) the crowder environment increases the diferric-Tf (Fe2Tf) stability against iron loss and overall denaturation of the protein, (ii) both in the absence and presence of crowder, the presence of salt promotes the loss of iron and overall denaturation of Fe2Tf which is due to ionic screening of electrostatic interactions, (iii) the crowder environment retards iron release from monoferric N-lobe of Tf (FeNTf) by increasing enthalpic barrier, (iv) the retardation of iron release by crowding is enthalpically dominated than the entropic one, (v) both in the absence and presence of crowder, the presence of salt accelerates the iron release from FeNTf due to ionic screening of electrostatic interactions and anion binding to KISAB sites, and (vi) the crowders environment is unable to diminish (a) the salt-induced destabilization of Fe2Tf against the loss of iron and overall denaturation and (b) the anion effect and ionic screening of diffusive counterions responsible to promote iron release from FeNTf. ? 2017 American Chemical Society.
Synergistic effect of pistachio shell powder and nano-zerovalent copper for chromium remediation from aqueous solution
(Springer Science and Business Media Deutschland GmbH, 2021-07-06T00:00:00) Kumar, Sandeep; Brar, Ravinderdeep Singh; Babu, J. Nagendra; Dahiya, Amarjeet; Saha, Sandip; Kumar, Avneesh
Pistachio shell powder supported nano-zerovalent copper (ZVC@PS) material prepared by borohydride reduction was characterized using SEM, FTIR, XRD, TGA/DTA, BET, and XPS. SEM, XRD, and XPS revealed the nano-zerovalent copper to consist of a core-shell structure with CuO shell and Cu(0) core with a particle size of 40�100 nm and spherical morphology aggregated on PS biomass. ZVC@PS was found to contain 39% (w/w %) Cu onto the pistachio shell biomass. Batch sorption of Cr(VI) from the aqueous using ZVC@PS was studied and was optimized for dose (0.1�0.5 g/L), initial Cr(VI) concentration(1�20 mg/L), and pH (2�12). Optimized conditions were 0.1 g/L doses of sorbent and pH=3 for Cr(VI) adsorption. Langmuir and Freundlich adsorption isotherm models fitted well to the adsorption behavior of ZVC@PS for Cr(VI) with a pseudo-second-order kinetic behavior. ZVC@PS (0.1g/L) exhibits qmax for Cr(VI) removal up to 110.9 mg/g. XPS and other spectroscopic evidence suggest the adsorption of Cr(VI) by pistachio shell powder, coupled with reductive conversion of Cr(VI) to Cr(III) by ZVC particles to produce a synergistic effect for the efficient remediation of Cr(VI) from aqueous medium. Graphical abstract: [Figure not available: see fulltext.] � 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Tetracycline removal via three-way synergy between pistachio shell powder, zerovalent copper or iron, and peroxymonosulfate activation
(Elsevier B.V., 2023-10-20T00:00:00) Kaur, Parminder; Kumar, Atul; Babu, J. Nagendra; Kumar, Sandeep
Pistachio shell powder (PS) immobilized zerovalent iron and zerovalent copper (ZVI@PS and ZVC@PS) were investigated for the tetracycline (TCH) removal via sulfate radical based advanced oxidation process (S-AOP's). Eco-efficient ZVI@PS and ZVC@PS nanocomposite prepared by one-pot redox precipitation method were characterized by using FTIR, XRD, SEM, BET, TGA/DTA, and XPS techniques. The EDX, TGA, and AAS analysis techniques confirmed the loading of 44 % Fe and 40 % Cu (w/w %) onto the pistachio shell biomass in ZVI@PS and ZVC@PS nanocomposites, respectively. This report comprehensively discusses the effect of various contributing factors for the TCH removal via advanced oxidation processes such as catalytic dosage, initial pH, PMS dosage and initial TCH concentrations, etc. Besides that, the role of reactive oxygen species (SO4?,.OH, O2?, and 1O2) in the TCH degradation process was investigated using radical scavenging experiments. A three-way synergistic approach was established between adsorption efficiencies of pistachio shell powder, heterogeneous ZVI or ZVC mediated Fenton-process and enhanced PMS activation process, for the observed enhanced TCH degradations. The observed rate constant (kobs.) values of ZVI@PS-PMS (0.34 min?1) and ZVC@PS-PMS (0.16 min?1) processes for TCH removal suggests that the ZVI@PS was more efficient in TCH removal compared to ZVC@PS. � 2023 The Author(s)
Trans-cinnamaldehyde mitigates rotenone-induced neurotoxicity via inhibiting oxidative stress in rats
(Elsevier B.V., 2022-12-21T00:00:00) Kumar, Sandeep; Kumar, Sachin; Arthur, Richmond; Kumar, Puneet
Background: The second most prevalent age-related brain condition, Parkinson's disease (PD) is characterised by the loss of neurons in the substantia nigra pars compacta (SNpc). It is associated with symptoms like bradykinesia, stiffness, tremor, and impaired postural responses. Motor dysfunction, and neurochemical imbalance, are involved in the pathophysiology of PD. It has been hypothesised that trans cinnamaldehyde (TCA) a component of Traditional Chinese Medicine (TCM) can ameliorate Parkinson-like symptoms by altering the levels of different biochemical markers and reverse motor impairments. This research sought to determine the neuroprotective effect of TCA against the neurotoxicity caused by rotenone. Basic Procedure: Rotenone (1.5 mg/kg/day; s.c. for 35 days) was given to rats to induce Parkinson-like symptoms. TCA (5, 10, and 20 mg/kg) and concomitant treatment of TCA (5 mg/kg) with L-NAME (10 mg/kg) were given one hour prior to rotenone administration. Every week until the 35th day, behavioral parameters (muscle coordination, spontaneous motor movement and gait abnormalities) were assessed using rotarod, actophotometer, and narrow beam apparatus respectfully. Rats were decapitated on the 35th day, the striatum and cortex were isolated for biochemical tests. Main findings: Rotenone treatment reduced body weight, altered motor coordination and reduced the oxidative defense system. Treatment with TCA significantly improved the alterations in antioxidant levels as well as behavioral parameters. Furthermore, L-NAME (nitric oxide synthase inhibitor) in combination with TCA had a more significant effect as compared to TCA alone, signifying a possible drug interaction. Principal conclusion: TCA could be employed as an adjuvant in PD management. � 2022 The Authors