Browsing by Author "Kumar, Vikas"

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    Preparation of a Pt(II)-3-Hydroxy-2-tolyl-4H-chromen-4-one Complex Having Antimicrobial, Anticancerous, and Radical Scavenging Activities with Related Computational Studies
    (American Chemical Society, 2023-08-22T00:00:00) Mohmad, Masrat; Agnihotri, Nivedita; Kumar, Vikas; Azam, Mohammad; Kamal, Raj; Kumar, Ashish; Sharma, Ujjawal; Javed, Saleem; Muthu, Sambantham; Min, Kim
    A novel benzopyran-based platinum (II)-3-hydroxy-2-tolyl-4H-chromen-4-one (HToC) complex has been prepared and studied by UV-visible spectrophotometry. The study is based on the colored complexation between Pt(II) and HToC in the pH range of 8.92-9.21, resulting in the formation of a stable binary yellow complex exhibiting ?max at 509-525 nm. The formed complex maintains linearity between 0.0 and 1.8 ?g Pt(II) mL-1. The well-known qualitative analytical methods, including Job�s method of continuous variations and the mole ratio approach, have both proven that the stoichiometry of the complex is 1:2 [Pt(II)/HToC]. Hence, the analytical results suggest that the formed platinum complex exhibits a square planar geometry. The values of various attributes corresponding to spectrophotometric studies and statistical calculations, such as the molar extinction coefficient (6.790 � 104 L mol-1 cm-1), Sandell�s sensitivity (0.0029 ?g Pt(II) cm-2), standard deviation (� 0.0011), RSD (0.317%), limit of detection (0.0147 ?g mL-1) and correlation coefficient (0.9999), show that the performed study satisfies all of the criteria for good sensitivity, versatility, and cost-effectiveness. In order to have an apprehension of the molecular geometry and other structural specifics of the complex, DFT studies have been carried out. The in vitro anticancer potential of the ligand and its platinum complex in the human breast cancer cell line (T-27D), as determined by the MTT assay, reveals that the complex has better antiproliferative potential than the ligand. The antimicrobial potential of the complex has been successfully tested against both Gram-positive and -negative bacteria. Antioxidant capacity results suggest the better radical scavenging capacity of the complex than that of the ligand. � 2023 The Authors. Published by American Chemical Society
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    Quantitative assessment of vegetation layers in tropical evergreen forests of Arunachal Pradesh, Eastern Himalaya, India
    (Indian Academy of Sciences, 2021-07-17T00:00:00) Dash, Sudhansu Sekhar; Panday, Samiran; Rawat, Dinesh Singh; Kumar, Vikas; Lahiri, Subhajit; Sinha, Bipin Kumar; Singh, Paramjit
    The present study deals with first-hand information on quantitative assessments of different vegetation layers (viz. trees, saplings, seedlings, shrubs and herbs) collected from 57 permanent plots (size 400 m2), established for long-term monitoring of biodiversity and study of functional aspects in Namdapha National Park (NPP), Arunachal Pradesh, Eastern Himalaya, India during 2017. We grouped all the plots into six clusters as study sites. A total of 60 taxa of trees, 67 shrubs and 81 herbs were recorded within 57 plots during the study. The average species richness per site for trees was 20.83 � 1.62, saplings 16.0 � 1.15, seedlings 15.83 � 1.35, shrubs 23.83 � 1.58 and herbs 32.67 � 0.92. Total stem density varied from 117.5 to and 181 ha?1 (152.58 � 10.04 ha?1) for trees (circumference ?31.5 cm), 881 to 3000 ha?1 (1652.17 � 317.61 ha?1) for shrubs and from 76750 to 98545 ha?1 (92032.17 � 3246.60 ha?1) for herbs. Tree regeneration status at all the six study sites was �good� (i.e. density of seedlings > saplings > trees). The distribution of tree stems (circumference ?31.5 cm) into different size classes showed highest relative density in the lowest stem size class (10�20 cm diameter) which also indicates good tree regeneration in the study area. Dipterocarpus retusus Blume was the most dominant tree species in the core zone area of NNP with �good� regeneration status. � 2021. All Rights Reserved.
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    Quantitative assessment of vegetation layers in tropical evergreen forests of Arunachal Pradesh, Eastern Himalaya, India
    (Indian Academy of Sciences, 2021-07-17T00:00:00) Dash, Sudhansu Sekhar; Panday, Samiran; Rawat, Dinesh Singh; Kumar, Vikas; Lahiri, Subhajit; Sinha, Bipin Kumar; Singh, Paramjit
    The present study deals with first-hand information on quantitative assessments of different vegetation layers (viz. trees, saplings, seedlings, shrubs and herbs) collected from 57 permanent plots (size 400 m2), established for long-term monitoring of biodiversity and study of functional aspects in Namdapha National Park (NPP), Arunachal Pradesh, Eastern Himalaya, India during 2017. We grouped all the plots into six clusters as study sites. A total of 60 taxa of trees, 67 shrubs and 81 herbs were recorded within 57 plots during the study. The average species richness per site for trees was 20.83 � 1.62, saplings 16.0 � 1.15, seedlings 15.83 � 1.35, shrubs 23.83 � 1.58 and herbs 32.67 � 0.92. Total stem density varied from 117.5 to and 181 ha?1 (152.58 � 10.04 ha?1) for trees (circumference ?31.5 cm), 881 to 3000 ha?1 (1652.17 � 317.61 ha?1) for shrubs and from 76750 to 98545 ha?1 (92032.17 � 3246.60 ha?1) for herbs. Tree regeneration status at all the six study sites was �good� (i.e. density of seedlings > saplings > trees). The distribution of tree stems (circumference ?31.5 cm) into different size classes showed highest relative density in the lowest stem size class (10�20 cm diameter) which also indicates good tree regeneration in the study area. Dipterocarpus retusus Blume was the most dominant tree species in the core zone area of NNP with �good� regeneration status. � 2021. All Rights Reserved.