Browsing by Author "Polina, Saibabu"

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    P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds
    (Wiley-VCH Verlag, 2020-11-20T00:00:00) Polina, Saibabu; Putta, V. P. Rama Kishore; Gujjarappa, Raghuram; Singh, Virender; Pujar, Prasad Pralhad; Malakar, Chandi C.
    A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.). � 2020 Wiley-VCH GmbH
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    Potassium tert-Butoxide-Mediated Synthesis of 2-Aminoquinolines from Alkylnitriles and 2-Aminobenzaldehyde Derivatives
    (John Wiley and Sons Inc, 2022-12-08T00:00:00) Kishore, Pendyala Satya; Gujjarappa, Raghuram; Putta, V. P. Rama Kishore; Polina, Saibabu; Singh, Virender; Malakar, Chandi C.; Pujar, Prasad Pralhad
    KOtBu mediates the reaction between 2-amino arylcarbaldehydes and benzyl/alkyl cyanides toward the expeditious formation of 2-aminoquinolines under transition-metal-free conditions. The described transformation proceeds through in-situ generated enimine intermediate from benzyl/alkyl cyanides under KOtBu-mediated reaction conditions. The substituted 2-aminoquinolines were realized in excellent yields at room temperature and shorter reaction time. The designed process exhibits operational simplicity and broad functional group tolerance in delivering the products of high significance. � 2022 Wiley-VCH GmbH.