Browsing by Author "Wong, L.S."

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    High-Resolution Scanning Probe Nanolithography of 2D Materials: Novel Nanostructures
    (Wiley, 2019) Rani, E; Wong, L.S.
    2D materials have attracted tremendous research interest since the isolation of graphene. Their remarkable optical, electronic, and mechanical properties show that they hold great potential across a range of technological applications. As a result, there is a growing demand for low-cost, low-energy, and high-resolution lithography methods that will enable the integration of 2D materials into complex integrated circuitry, biomedical devices, and in the generation of quantum-confined nanostructures. Recent advances in scanning probe nanolithography (SPL) techniques for the lithography of 2D materials such as graphene, black phosphorus, molybdenum disulfide, and tungsten diselenide are discussed, including the various physiochemical aspects of subtractive and additive lithography of these materials. Examples of 2D-material-based devices fabricated by SPL and their properties are also described. The comparative advantages of the individual SPL techniques are discussed along with the future outlook of SPL for 2D materials. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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    Polymer pen lithography-fabricated DNA arrays for highly sensitive and selective detection of unamplified Ganoderma boninense DNA
    (MDPI AG, 2019) Rani, Ekta; Mohshim, S.A; Ahmad, M.Z; Goodacre, R; Ahmad ,S.A.A; Wong, L.S.
    There is an increasing demand for lithography methods to enable the fabrication of diagnostic devices for the biomedical and agri-food sectors. In this regard, scanning probe lithography methods have emerged as a possible approach for this purpose, as they are not only convenient, robust and accessible, but also enable the deposition of "soft" materials such as complex organic molecules and biomolecules. In this report, the use of polymer pen lithography for the fabrication of DNA oligonucleotide arrays is described, together with the application of the arrays for the sensitive and selective detection of Ganoderma boninense, a fungal pathogen of the oil palm. When used in a sandwich assay format with DNA-conjugated gold nanoparticles, this system is able to generate a visually observable result in the presence of the target DNA. This assay is able to detect as little as 30 ng of Ganoderma-derived DNA without any pre-amplification and without the need for specialist laboratory equipment or training. © 2019 by the authors.