Mathematics And Statistics - Research Publications

Permanent URI for this collectionhttps://kr.cup.edu.in/handle/32116/47

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    Fractional time-delay mathematical modeling of Oncolytic Virotherapy
    (Elsevier Ltd, 2021-06-19T00:00:00) Kumar, Pushpendra; Erturk, Vedat Suat; Yusuf, Abdullahi; Kumar, Sunil
    An emerging treatment tool which uses replication-competent viruses to dissipate cancers without causing deficit to normal tissues, named as oncolytic virotherapy, is discussed in the article. We analysed a fractional delay dynamical model on the oncolytic virotherapy compositing viral lytic cycle and virus-specific cytotoxic T lymphocyte (CTL) response. We used a well known Caputo fractional derivative to analyse the structure of the given dynamical model. Using the literature of fixed-point theory, the given time-delay model is specified to have existence of a unique solution. We established different types of graphical simulations for the various values of R0 and R1. We observed a different behaviour of the given fractional model as compare to the integer order model. The given algorithm is smooth in use and reliable to apply on different delay dynamical models. � 2021 Elsevier Ltd
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    A study on canine distemper virus (CDV) and rabies epidemics in the red fox population via fractional derivatives
    (Elsevier B.V., 2021-05-05T00:00:00) Kumar, Pushpendra; Erturk, Vedat Suat; Yusuf, Abdullahi; Nisar, Kottakkaran Sooppy; Abdelwahab, Sayed F.
    Several deadly epidemics that have recognized as serious problems all over the world in the last few decades. Lassa hemorrhagic fever, coronavirus, dengue fever, malaria, and HIV are well-known deadly diseases in humans. In this research, we analysed the dynamics of the canine distemper virus (CDV) and rabies epidemics in the red fox population of the northern region of Italy with the help of time-fractional models. We performed our analysis in the new generalized Caputo non-classical derivative sense with the application of the Predictor�Corrector algorithm. We used the data of northern Italy for simulations and estimated the endemic equilibrium points for both CDV and rabies models. Also, we presented the local stability of disease-free equilibrium points. Some theorems are mentioned for the purpose of existence and uniqueness analysis. Our results are perfect for giving an idea of the dynamics of the CDV and rabies epidemic in northern Italy. The dynamics of the given solutions are specified with the help of necessary graphical simulations. The projected algorithm is so effective in finding the solutions of complex dynamical systems. By this study, we give an idea of how applied mathematics is directly connected to biological studies. The major scientific aim of this study is to understand the outbreaks of CDV and rabies on the population of the red foxes by using the texture of fractional mathematical models. � 2021 The Authors