Pharmaceutical Sciences and Natural Products - Research Publications

Permanent URI for this collectionhttps://kr.cup.edu.in/handle/32116/56

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Author: search.filters.author.Gochev, Velizar K.Subject: search.filters.subject.Biting deterrent activity

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    Chemical composition and biological activity of essential oils of dracocephalum heterophyllum benth And Hyssopus officinalis L Collected wild from Western Himalay
    (Sage, 2015) Stappena, Iris; Wannerb Jürgen; Tabanca, Nurhayat; Wedge, David E.; Ali, Abbas; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar K.; Schmidt, Erich; Jirovetz, Leopold
    The essential oils of two representatives of the Lamiaceae, Dracocephalum heterophyllum Benth. and Hyssopus officinalis L., are described for their antifungal, antibacterial, larvicidal and inect biting deterrent activities. Additionally, the chemical compositions of the essential oils, analyzed by simultaneous GC-MS and GC-FID, and odor descriptions are given. The main components of H. officinalis oil were pinocarvone, cis-pinocamphone, and ?-pinene. Citronellol was found as the main compound of D. heterophyllum essential oil. Antibacterial testing by agar dilution assay revealed greater activity of D. heterophyllum against Staphylococcus aureus compared with H. officinalis. D. heterophyllum essential oil also showed promising antifungal activity against Colletotrichum species and was more toxic to Aedes aegypti larvae in a larvicial bioassay. Both essential oils showed high activity in the biting deterrent bioassay.
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    Chemical Composition and Biological Activity of Essential Oils from Wild Growing Aromatic Plant Species of Skimmia laureola and Juniperusmacropoda from Western Himalaya
    (NPC (Natural Product Communication), 2015) Stappena,Iris; Tabanca, Nurhayat; Ali, Abbas; Wedge, David E.; Wanner, J�rgen; Kaul, Vijay K.; Lal, Brij; Jaitak, Vikas; Gochev, Velizar K.; Schmidt, Erich; Jirovetz, Leopold
    The Himalayan region is very rich in a great variety of medicinal plants. In this investigation the essential oils of two selected species are described for their antimicrobial and larvicidal as well as biting deterrent activities. Additionally, the odors are characterized. Analyzed by simultaneous GC-MS and GC-FID, the essential oils’ chemical compositions are given. The main components of Skimmia laureola oil were linalool and linalyl acetate whereas sabinene was found as the main compound for Juniperus macropoda essential oil. Antibacterial testing by agar dilution assay revealed highest activity of S. laureola oil against all tested bacteria, followed by J. macropoda oil . Antifungal activity was evaluated against the strawberry anthracnose causing plant pathogens Colletotrichum acutatum , C. fragariae and C . gloeosporioides . Juniperus macropoda essential oil indicated higher antifungal activity against all three pathogens than S. laureola oil. Both essential oils showed biting deterrent activity above solvent control but low larvicidal activity.