Department Of Pharmaceutical Sciences and Natural Products

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Author: search.filters.author.Jaitak, VikasSubject: search.filters.subject.Asparagus racemosus

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    SHATAVARI (ASPARAGUS RACEMOSUS WILD): A REVIEW ON ITS CULTIVATION, MORPHOLOGY, PHYTOCHEMISTRY AND PHARMACOLOGICAL IMPORTANCE
    (web of Science (Thomson Reuters), 2014) Singla, Ramit; Jaitak, Vikas
    Asparagus racemosus, a climbing Ayurvedic plant, is known for its numerous activities such as hyperlipidemia, hypertension, angina, dysmenorrhea, anxiety disorders, benign prostatic hyperplasia (BPH), leucorrhoea and urinary tract infections. This plant possesses a wide range of secondary metabolites inclusive of steroids, alkaloids, dihydrophenanthrene derivatives, flavonoids, furan derivatives and essential oils. Information from the literature suggests that, the major constituents of A. racemosus are steroidal saponins which are mainly responsible for different biological activities of A. racemosus. The review summarizes the information concerning the cultivation, morphology, phytochemistry, biological activities, safety profile, marketing status and conservation techniques of A. racemosus .
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    In-vitro anti-mutagenic activity of Asparagus racemosus: An ayurvedic medicinal plant
    (Academic Journals Inc., 2013) Singh, Ramit; Kaur, Rajbir; Arora, Saroj; Jaitak, Vikas
    Asparagus racemosus is a plant traditionaly used in epilepsy, as a brain tonic, cardiac disorders, hypertension, habitual abortions, weakness of the uterus, excessive bleeding during menstruation. The current study evaluated the antimutagenic pottential of methanolic (RME) and aqueous methanolic extract (RAE) extracted from A. racemosus. Ames assay was used to acess the antimutagenic potential of RME and RAE (2.5x103, 1.0x103, 0.5x103, 0.25x103, 0.10x103 and 0.01x103 ?g 0.1 mL plate-1) that was added with mutagenic activation of TA98 and TA100 strain of Salmonella typhimurium. A. racemosus extract RME and RAE have been found to have effective in the inhibition of mutation induced by NPD and sodium azide. Among the two extracts, RAE showed maximum inhibition of 49.2% followed by RME having inhibition of 40.63% in Co-incubation mode. Current study indicated that A. racemosus can be used as a new source of anti-mutagenic. ? 2013 Academic Journals Inc.