School Of Basic And Applied Sciences

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    Mandelic acid catalyzed one-pot pseudo three-component synthesis of various trisubstituted methane derivatives at room temperature
    (Arkat, 2022-11-03T00:00:00) Banerjee, Bubun; Singh, Arvind; Sharma, Aditi; Priya, Anu; Kaur, Manmeet; Kaur, Gurpreet; Gupta, Vivek Kumar; Jaitak, Vikas
    A simple, mild, eco-friendly, general and convenient approach has been developed for the synthesis of various trisubstituted methane derivatives via one-pot pseudo three-component reactions between one equivalent of aromatic aldehydes and two equivalents of 6-amino-uracils or dimedone respectively using a catalytic amount of mandelic acid as a low cost, commercially available, efficient organo-catalyst in aqueous ethanol at room temperature. � 2022 Arkat. All rights reserved.