School Of Basic And Applied Sciences

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    Iron content titanium dioxide nanoparticles as exogenous contrast agent for tissue imaging using swept-source optical coherence tomography
    (American Institute of Physics Inc., 2021-01-08T00:00:00) Barkhade, Tejal; Indoliya, Abhishek; Poddar, Raju; Mahapatra, Santosh Kumar; Banerjee, Indrani
    Ex vivo tissue imaging was performed by swept-source optical coherence tomography (SS-OCT) using titanium dioxide (TiO2) and Fe content TiO2 nanoparticles (NPs). The comparative effects of TiO2 and Fe content TiO2 NPs in terms of contrast enhancement, penetration, scattering, and accumulation in the chicken breast tissue have been monitored at different exposure times. Powder NP samples were synthesized using the sol-gel method, and characterization was carried out via transmission electron microscopy, x-ray photoelectron spectroscopy, and diffuse reflectance spectroscopy techniques. Fe incorporation in the TiO2 matrix reduces its toxic effect on tissue skin and produces a safe exogenous contrast agent, which is analyzed by SS-OCT. The scattering coefficients and contrast to noise ratio of the tissues with and without NPs were determined to study the imaging efficacy. The improvement in the coefficient was observed with an increase in the exposure time of NPs. Nano-TiO2 has shown the ability to penetrate within the tissue layer up to 780 ?m while Fe content TiO2 NPs samples showed the lowest rate of penetration up to 210 ?m after a 30 min time interval. � 2021 Author(s).
  • Item
    Cellulose: A multifaceted biopolymer
    (Nova Science Publishers, Inc., 2016) Majeed, A.; Najar, R.A.; Ul Rehman, W.; Choudhary, S.; Thakur, S.; Singh, A.; Sharma, G.; Bhardwaj, P.
    Cellulose is a common natural polymer with a wide range of industrial, medical, bio fuel, agricultural, textile and paper applications. It exhibits various levels of structural organizations, from individual glucose chains through microfibrils, macrofibrils to cellulose fibers. The synthesizing machinery of cellulose consists of a six subunit plasmamembrane protein complex, cellulose synthase, organized into a rosette structure. Plant cellulose synthases possess additional plant specific motifs that are absent in bacteria. Among the different solvent systems developed for cellulose dissolution, ionic liquids stand at the forefront. Microorganism mediated energy release from cellulose facilitates its use in fuel cells as a source of energy. The nanocomposites of cellulose have revolutionized the medical field and are being chiefly used in tissue engineering, ligament engineering and wound healing. The chemical structure of cellulose make it suitable to form hydrogels which are used in tissue engineering, cartilage modelling, bone implantation, cell culture scaffolds, enhanced drug delivery, heavy metal absorbance, and in retaining soil water and efficient fertilizer release for agricultural efficiency. Besides, cellulose based ethanol production help to reduce the pressure on conventional sources of energy. This chapter focuses on cellulose structure, its synthesizing machinery, trafficking, genes and proteins involved, solubility and solvent systems, its derivatives, composites, hydrogels, fuel cells, ethanol production and degradation. ? 2016 Nova Science Publishers, Inc.