School Of Basic And Applied Sciences

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Subject: search.filters.subject.C-reactive protein

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    Role of plant-based bioactive nutritional or dietary supplements in the metabolic syndrome of women and children during Covid-19
    (Apple Academic Press, 2023-08-04T00:00:00) Yashi, Srivastava; Awasthi, Ankit
    Metabolic syndrome includes obesity, type 2 diabetes (T2D) mellitus, hypertension, dyslipidemia, and inflammation showing detrimental result in women and children on the immune response to COVID-19. The plants are the best sources for the production of bioactive compounds like polyphenol, flavonoids, etc. (Keservani and Sharma, 2014). These compounds have properties to improve the functionality of many receptors (insulin IR, AMPK, TNF, and TNFR, cytokine receptor, IL-1, ILR, TNF, TNFR, and PPARG) that can control internal factors (LDL, VLDL, HDL, triglycerides, glucose level, C-reactive protein (CRP), erythrocytes, heart rate and blood pressure) which eventually reduces the risk of metabolic syndrome. The processing, digestibility, and functionality of bioactive constituents from plants helps in the consumption of nutraceutical supplements through many government schemes and decreases the cases of metabolic syndrome in many countries. � 2023 Apple Academic Press, Inc.
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    Role of plant-based bioactive nutritional or dietary supplements in the metabolic syndrome of women and children during Covid-19
    (Apple Academic Press, 2023-08-04T00:00:00) Yashi, Srivastava; Awasthi, Ankit
    Metabolic syndrome includes obesity, type 2 diabetes (T2D) mellitus, hypertension, dyslipidemia, and inflammation showing detrimental result in women and children on the immune response to COVID-19. The plants are the best sources for the production of bioactive compounds like polyphenol, flavonoids, etc. (Keservani and Sharma, 2014). These compounds have properties to improve the functionality of many receptors (insulin IR, AMPK, TNF, and TNFR, cytokine receptor, IL-1, ILR, TNF, TNFR, and PPARG) that can control internal factors (LDL, VLDL, HDL, triglycerides, glucose level, C-reactive protein (CRP), erythrocytes, heart rate and blood pressure) which eventually reduces the risk of metabolic syndrome. The processing, digestibility, and functionality of bioactive constituents from plants helps in the consumption of nutraceutical supplements through many government schemes and decreases the cases of metabolic syndrome in many countries. � 2023 Apple Academic Press, Inc.
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    Association of elevated levels of C-reactive protein with breast cancer, breast cancer subtypes, and poor outcome
    (Mosby Inc., 2019) Kaur R.P.; Rubal; Banipal R.P.S.; Vashistha R.; Dhiman M.; Munshi A.
    Background and Purpose: Inflammation and caner are linked in a bidirectional manner. C-reactive protein (CRP) is an important inflammatory marker. The aim of the study was to test whether the inflammatory marker, CRP at the time of diagnosis of breast cancer is associated with metastasis, recurrence, and death in breast cancer patients from Malwa region of Punjab where breast cancer is widely feared. Material and Methods: Two hundred and forty-two breast cancer patients and 242 age and sex matched controls were included in the study. CRP levels were estimated using fully automated bio analyzer Erba200. Follow up interviews were conducted at an interval of 3, 6, 9, 12, 15, 18, 21, 24, and 27 months to determine the outcome among breast cancer patients. Results: Elevated levels of CRP were found among the diseased in comparison with controls (P < 0.0001). Higher CRP levels associated significantly with poor outcome including metastasis and recurrence among breast cancer patients [P = 0.03; 95% confidence interval; odds ratio: 2.954 (0.9125-9.561)]. Conclusion: Elevated levels of CRP associated significantly with increased risk of breast cancer and poor outcome. CRP estimation may be a simple and inexpensive tool for the risk assessment and outcome of the disease in Malwa region of Punjab where incidence of breast cancer is reported to be very high.