School Of Basic And Applied Sciences

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Subject: search.filters.subject.Encapsulation

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    Encapsulation for efficient spray drying of fruit juices with bioactive retention
    (Springer, 2022-06-17T00:00:00) Srivastava, Soma; Bansal, Mrigya; Jain, Dilip; Srivastava, Yashi
    Higher moisture content and inefficient post-harvest handling result in huge losses and scanty availability of the fruits. Spray drying is one such technique to handle the problem of post-harvest losses as powder production not only cuts the storage and transportation cost but also provides higher shelf stability. This review provides a detailed description of the process of spray drying and the effect of each parameter on powder characteristics. It also summarizes that addition of different wall materials resulted in the production of high-quality fruit juice powders.There are two major approaches material based i.e., encapsulation and process-based which aim to improve the economic value of spray drying by controlling the problems of stickiness, hygroscopicity, and thermal degradation of heat-sensitive compounds. Stickiness is majorly due to the low glass transition temperature of fruit juices (sugars and acids) which is elevated with the addition of encapsulating agents. Control over operational parameters is essential to deliver fruit powders within acceptable quantity and quality, both in terms of organoleptic and nutritional parameters. Various studies revealed that encapsulation act as protective shield for bioactive and probiotics retention. Maltodextrin (Dextrose equivalence 10�20) is reported as the most efficient drying aid. Prebiotics like nutriose and skimmed milk powder can also be used as drying aids. Most suitable conditions for spray drying of fruit juices like pomegranate, ber, and jamun are 25% maltodextrin at 124��C, 8�10% maltodextrin at 160�190��C, and 10% maltodextrin at 185��C, respectively. � 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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    Encapsulation for efficient spray drying of fruit juices with bioactive retention
    (Springer, 2022-06-17T00:00:00) Srivastava, Soma; Bansal, Mrigya; Jain, Dilip; Srivastava, Yashi
    Higher moisture content and inefficient post-harvest handling result in huge losses and scanty availability of the fruits. Spray drying is one such technique to handle the problem of post-harvest losses as powder production not only cuts the storage and transportation cost but also provides higher shelf stability. This review provides a detailed description of the process of spray drying and the effect of each parameter on powder characteristics. It also summarizes that addition of different wall materials resulted in the production of high-quality fruit juice powders.There are two major approaches material based i.e., encapsulation and process-based which aim to improve the economic value of spray drying by controlling the problems of stickiness, hygroscopicity, and thermal degradation of heat-sensitive compounds. Stickiness is majorly due to the low glass transition temperature of fruit juices (sugars and acids) which is elevated with the addition of encapsulating agents. Control over operational parameters is essential to deliver fruit powders within acceptable quantity and quality, both in terms of organoleptic and nutritional parameters. Various studies revealed that encapsulation act as protective shield for bioactive and probiotics retention. Maltodextrin (Dextrose equivalence 10�20) is reported as the most efficient drying aid. Prebiotics like nutriose and skimmed milk powder can also be used as drying aids. Most suitable conditions for spray drying of fruit juices like pomegranate, ber, and jamun are 25% maltodextrin at 124��C, 8�10% maltodextrin at 160�190��C, and 10% maltodextrin at 185��C, respectively. � 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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    Polymeric Encapsulates of Essential Oils and Their Constituents: A Review of Preparation Techniques, Characterization, and Sustainable Release Mechanisms
    (Taylor and Francis Inc., 2016) Vishwakarma, G.S.; Gautam, N.; Babu, J.N.; Mittal, S.; Jaitak, Vikas
    Natural polymer based encapsulation of essential oil (EO) is one of the emerging and challenging area of research in perfumery, cosmetics, flavoring agents, preservatives, therapeutics, etc. The knowledge of formulation techniques and physico-chemical properties of the polymers are the basic requirements for the successful encapsulations of essential oils (EOs). This current review article is focused on a comparative account of various formulation techniques based on their applicability. For the first time, it also reviews various physico-chemical techniques used in the analysis of EO encapsulates to determine their stability, structure, surface morphology, and encapsulation efficiency. Further, the mechanisms involved in the release of EOs from encapsulates, along with various factors affecting their release, have also been discussed. ? 2016 Taylor & Francis Group, LLC.
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    Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes
    (2012) Malhi, Sarandeep Singh; Budhiraja, Abhishek; Arora, Sumit; Chaudhari, Kiran R.; Nepali, Kunal; Kumar, Raj; Sohi, Harmik; Murthy, Rayasa S.R.
    Cancer cells reflect higher level of ROS in comparison to the normal cell, so they become more vulnerable to further oxidative stress induced by exogenous ROS-generating agents. Through this a novel therapeutic strategy has evolved, which involves the delivery of redox cycler-doxorubicin (DOX) to the mitochondria of cancer cell where it acts as a source of exogenous ROS production. The purpose of this study is to develop a liposomal preparation which exhibits a propensity to selectively target cancer cell along with the potential of delivering drug to mitochondria of cell. We have rendered liposomes mitocancerotropic (FA-MTLs) by their surface modification with dual ligands, folic acid (FA) for cancer cell targeting and triphenylphosphonium (TPP) cations for mitochondria targeting. The cytotoxicity, ROS production and cell uptake of doxorubicin loaded liposomes were evaluated in FR (+) KB cells and found to be increased considerably with FA-MTLs in comparison to folic acid appended, mitochondria targeted and non-targeted liposomes. As confirmed by confocal microscopy, the STPP appended liposomes delivered DOX to mitochondria of cancer cell and also showed higher ROS production and cytotoxicity in comparison to folic acid appended and non-targeted liposomes. Most importantly, mitocancerotropic liposomes showed superior activity over mitochondria targeted liposomes which confirm the synergistic effect imparted by the presence of dual ligands - folic acid and TPP on the enhancement of cellular and mitochondrial delivery of doxorubicin in KB cells. ? 2012 Elsevier B.V. All rights reserved.