Potassium tert-Butoxide-Mediated Synthesis of 2-Aminoquinolines from Alkylnitriles and 2-Aminobenzaldehyde Derivatives

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dc.contributor.authorKishore, Pendyala Satya
dc.contributor.authorGujjarappa, Raghuram
dc.contributor.authorPutta, V. P. Rama Kishore
dc.contributor.authorPolina, Saibabu
dc.contributor.authorSingh, Virender
dc.contributor.authorMalakar, Chandi C.
dc.contributor.authorPujar, Prasad Pralhad
dc.date.accessioned2024-01-21T10:33:05Z
dc.date.accessioned2024-08-13T11:16:18Z
dc.date.available2024-01-21T10:33:05Z
dc.date.available2024-08-13T11:16:18Z
dc.date.issued2022-12-08T00:00:00
dc.description.abstractKOtBu mediates the reaction between 2-amino arylcarbaldehydes and benzyl/alkyl cyanides toward the expeditious formation of 2-aminoquinolines under transition-metal-free conditions. The described transformation proceeds through in-situ generated enimine intermediate from benzyl/alkyl cyanides under KOtBu-mediated reaction conditions. The substituted 2-aminoquinolines were realized in excellent yields at room temperature and shorter reaction time. The designed process exhibits operational simplicity and broad functional group tolerance in delivering the products of high significance. � 2022 Wiley-VCH GmbH.en_US
dc.identifier.doi10.1002/slct.202204238
dc.identifier.issn23656549
dc.identifier.urihttp://10.2.3.109/handle/32116/3261
dc.identifier.urlhttps://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202204238
dc.language.isoen_USen_US
dc.publisherJohn Wiley and Sons Incen_US
dc.subject2-Amino arylcarbaldehydesen_US
dc.subject2-Aminoquinolinesen_US
dc.subjectAlkyl cyanidesen_US
dc.subjectKO<sup>t</sup>Buen_US
dc.subjectTransition-metal-freeen_US
dc.titlePotassium tert-Butoxide-Mediated Synthesis of 2-Aminoquinolines from Alkylnitriles and 2-Aminobenzaldehyde Derivativesen_US
dc.title.journalChemistrySelecten_US
dc.typeArticleen_US
dc.type.accesstypeClosed Accessen_US

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