Recent advances in the C(1)-functionalization of tetrahydroisoquinolines via multicomponent reactions
| dc.contributor.author | Kaur, P | |
| dc.contributor.author | Kumar, R. | |
| dc.date.accessioned | 2020-07-16T07:41:56Z | |
| dc.date.accessioned | 2024-08-13T11:16:35Z | |
| dc.date.available | 2020-07-16T07:41:56Z | |
| dc.date.available | 2024-08-13T11:16:35Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | (Figure presented.) 1,2,3,4-Tetrahydroisoquinoline is an important structural motif of various natural products and therapeutic lead compounds. In recent years, considerable research interest has been witnessed toward synthesis of its C(1)-substituted derivatives, since they can act as precursors for various alkaloids displaying multifarious biological activities. This minireview offers short and non-exhaustive epitome of various multicomponent reactions for the C(1)-functionalization of 1,2,3,4-tetrahydroisoquinolines. In particular, reactions involving isomerization of iminium intermediate (exo/endo isomerization) are highlighted for the period of 2013-2019. - 2020, Springer Science+Business Media, LLC, part of Springer Nature. | en_US |
| dc.identifier.doi | 10.1007/s10593-020-02677-6 | |
| dc.identifier.issn | 93122 | |
| dc.identifier.uri | https://kr.cup.edu.in/handle/32116/2663 | |
| dc.identifier.url | https://link.springer.com/article/10.1007%2Fs10593-020-02677-6 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Springer | en_US |
| dc.subject | C(1)-functionalization | en_US |
| dc.subject | heterocyclic compounds | en_US |
| dc.subject | iminium ion | en_US |
| dc.subject | multicomponent reactions | en_US |
| dc.subject | tetrahydroisoquinoline | en_US |
| dc.title | Recent advances in the C(1)-functionalization of tetrahydroisoquinolines via multicomponent reactions | en_US |
| dc.title.journal | Chemistry of Heterocyclic Compounds | en_US |
| dc.type | Article | en_US |
| dc.type.accesstype | Closed Access | en_US |
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