Advances in arsenic biosensor development - a comprehensive review
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Ltd
Abstract
Biosensors are analytical devices having high sensitivity, portability, small sample requirement and ease of use for qualitative and quantitative monitoring of various analytes of human importance. Arsenic (As), owing to its widespread presence in nature and high toxicity to living creatures, requires frequent determination in water, soil, agricultural and food samples. The present review is an effort to highlight the various advancements made so far in the development of arsenic biosensors based either on recombinant whole cells or on certain arsenic-binding oligonucleotides or proteins. The role of futuristic approaches like surface plasmon resonance (SPR) and aptamer technology has also been discussed. The biomethods employed and their general mechanisms, advantages and limitations in relevance to arsenic biosensors developed so far are intended to be discussed in this review.
Description
Keywords
Aptamer, Ars operon, Arsenic toxicity, Biosensor, Recombinant whole cell, Reporter proteins
Citation
Kaur H., Kumar R., Babu J.N. et.al. (2015) Advances in arsenic biosensor development - a comprehensive review