Prevalence of soil-transmitted helminth infections in HIV patients: a systematic review and meta-analysis

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dc.contributor.authorAkanksha, Kumari
dc.contributor.authorKumari, Ashu
dc.contributor.authorDutta, Omprokash
dc.contributor.authorPrasanth, Ajay
dc.contributor.authorDeeba, Farah
dc.contributor.authorSalam, Nasir
dc.date.accessioned2024-01-21T10:26:45Z
dc.date.accessioned2024-08-13T11:19:33Z
dc.date.available2024-01-21T10:26:45Z
dc.date.available2024-08-13T11:19:33Z
dc.date.issued2023-07-08T00:00:00
dc.description.abstractSoil-transmitted Helminth (STH) infections have been found associated with people living with human immunodeficiency virus (HIV) but little is known about the overall burden of STH coinfection in HIV patients. We aimed to assess the burden of STH infections among HIV patients. Relevant databases were systematically searched for studies reporting the prevalence of soil-transmitted helminthic pathogens in HIV patients. Pooled estimates of each helminthic infection were calculated. The odds ratio was also determined as a measure of the association between STH infection and the HIV status of the patients. Sixty-one studies were finally included in the meta-analysis, consisting of 16,203 human subjects from all over the world. The prevalence of Ascaris lumbricoides infection in HIV patients was found to be 8% (95% CI 0.06, 0.09), the prevalence of Trichuris trichiura infection in HIV patients was found to be 5% (95% CI 0.04, 0.06), the prevalence of hookworm infection in HIV patients was found to be 5% (95% CI 0.04, 0.06), and prevalence of Strongyloides stercoralis infection in HIV patients was found to be 5% (95% CI 0.04, 0.05). Countries from Sub-Saharan Africa, Latin America & Caribbean and Asia were identified with the highest burden of STH-HIV coinfection. Our analysis indicated that people living with HIV have a higher chance of developing Strongyloides stercoralis infections and decreased odds of developing hookworm infections. Our findings suggest a moderate level of prevalence of STH infections among people living with HIV. The endemicity of STH infections and HIV status both are partially responsible for the burden of STH-HIV coinfections. � 2023, The Author(s).en_US
dc.identifier.doi10.1038/s41598-023-38030-y
dc.identifier.issn20452322
dc.identifier.urihttp://10.2.3.109/handle/32116/3122
dc.identifier.urlhttps://www.nature.com/articles/s41598-023-38030-y
dc.language.isoen_USen_US
dc.publisherNature Researchen_US
dc.subjectAnimalsen_US
dc.subjectAscariasisen_US
dc.subjectAscaris lumbricoidesen_US
dc.subjectCoinfectionen_US
dc.subjectFecesen_US
dc.subjectHelminthiasisen_US
dc.subjectHelminthsen_US
dc.subjectHIVen_US
dc.subjectHIV Infectionsen_US
dc.subjectHookworm Infectionsen_US
dc.subjectHumansen_US
dc.subjectPrevalenceen_US
dc.subjectSoilen_US
dc.subjectStrongyloidiasisen_US
dc.subjectanimalen_US
dc.subjectascariasisen_US
dc.subjectAscaris lumbricoidesen_US
dc.subjectcoinfectionen_US
dc.subjectcomplicationen_US
dc.subjectfecesen_US
dc.subjecthelminthen_US
dc.subjecthelminthiasisen_US
dc.subjecthookworm infectionen_US
dc.subjecthumanen_US
dc.subjectHuman immunodeficiency virusen_US
dc.subjectHuman immunodeficiency virus infectionen_US
dc.subjectmeta analysisen_US
dc.subjectprevalenceen_US
dc.subjectsoilen_US
dc.subjectstrongyloidiasisen_US
dc.titlePrevalence of soil-transmitted helminth infections in HIV patients: a systematic review and meta-analysisen_US
dc.title.journalScientific Reportsen_US
dc.typeArticleen_US
dc.type.accesstypeOpen Accessen_US

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