P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds
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Date
2020-11-20T00:00:00
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Publisher
Wiley-VCH Verlag
Abstract
A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.). � 2020 Wiley-VCH GmbH
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Keywords
Benzothiazin-4-ones, Cascade reaction, N,S-heterocycles, P(NMe<sub>2</sub>)<sub>3</sub>, Spiro compounds