Association of CYP2C19*2 and ALDH1A1*1/*2 variants with disease outcome in breast cancer patients: results of a global screening array.

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dc.contributor.authorKalra, Sourav
dc.contributor.authorLudhiadch Abhilash
dc.contributor.authorShafi, Gowhar
dc.contributor.authorVashista, Rajesh
dc.contributor.authorKumar, Raj
dc.contributor.authorMunshi, Anjana
dc.date.accessioned2019-03-26T09:06:58Z
dc.date.accessioned2024-08-13T12:06:33Z
dc.date.available2019-03-26T09:06:58Z
dc.date.available2024-08-13T12:06:33Z
dc.date.issued2018
dc.description.abstractCyclophosphamide and doxorubicin (adjuvant chemotherapy) are commonly used to treat breast cancer patients. Variation in the genes involved in pharmacodynamics and pharmacokinetics of these drugs plays an important role in prediction of drug response and survival. The present study was carried out with an aim to evaluate the variation in all the genes involved in pharmacokinetic and pharmacodynamics pathways of cyclophosphamide and doxorubicin, and correlate specific variants with disease outcome in breast cancer patients from the Malwa region of Punjab.en_US
dc.identifier.citationKalra, Sourav., Ludhiadch Abhilash., Shafi, Gowhar and et. al. (2018) Association of CYP2C19*2 and ALDH1A1*1/*2 variants with disease outcome in breast cancer patients: results of a global screening array. European Journal of Clinical Pharmacology. Vol. 74 (10), PP. 1291-1298. https://doi.org/10.1007/s00228-018-2505-6en_US
dc.identifier.doi10.1007/s00228-018-2505-6
dc.identifier.issnPrint- 0031-6970
dc.identifier.issnOnline- 1432-1041
dc.identifier.urihttp://10.2.3.109/handle/32116/2242
dc.identifier.urlhttps://link.springer.com/article/10.1007/s00228-018-2505-6
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.subjectPharmacogeneticsen_US
dc.subjectGene variantsen_US
dc.subjectGlobal screening arrayen_US
dc.subjectDisease outcomeen_US
dc.subjectYP2C19*2en_US
dc.subjectALDH1A1*1/*2en_US
dc.titleAssociation of CYP2C19*2 and ALDH1A1*1/*2 variants with disease outcome in breast cancer patients: results of a global screening array.en_US
dc.title.journalEuropean Journal of Clinical Pharmacologyen_US
dc.typeArticleen_US
dc.type.accesstypeOpen Accessen_US

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