Trehalose and its Diverse Biological Potential

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dc.contributor.authorSharma, Eva
dc.contributor.authorShruti, P.S.
dc.contributor.authorSingh, Shagun
dc.contributor.authorSingh, Tashvinder
dc.contributor.authorKaur, Prabhsimran
dc.contributor.authorJodha, Bhavana
dc.contributor.authorSrivastava, Yashi
dc.contributor.authorMunshi, Anjana
dc.contributor.authorSingh, Sandeep
dc.date.accessioned2024-01-16T14:22:46Z
dc.date.accessioned2024-08-13T10:13:36Z
dc.date.available2024-01-16T14:22:46Z
dc.date.available2024-08-13T10:13:36Z
dc.date.issued2023-06-07T00:00:00
dc.description.abstractTrehalose, a disaccharide molecule of natural origin, is known for its diverse biological ap-plications, like in drug development, research application, natural scaffold, stem cell preservation, food, and various other industries. This review has discussed one such diverse molecule �trehalose aka mycose�, and its diverse biological applications with respect to therapeutics. Due to its inertness and higher stability at variable temperatures, it has been developed as a preservative to store stem cells, and later, it has been found to have anticancer properties. Trehalose has recently been associated with modulating cancer cell metabolism, diverse molecular processes, neuroprotective effect, and so on. This article describes the development of trehalose as a cryoprotectant and protein stabilizer as well as a dietary component and therapeutic agent against various diseases. The article discusses its role in diseases via modulation of autophagy, various anticancer pathways, metabolism, inflammation, aging and oxidative stress, cancer metastasis and apoptosis, thus highlighting its diverse biological potential. � 2023 Bentham Science Publishers.en_US
dc.identifier.doi10.2174/1389203724666230606154719
dc.identifier.issn13892037
dc.identifier.urihttps://doi.org/10.2174/1389203724666230606154719
dc.identifier.urihttp://10.2.3.109/handle/32116/2828
dc.language.isoen_USen_US
dc.publisherBentham Science Publishersen_US
dc.subjectanti-inflammatoryen_US
dc.subjectbiological potentialen_US
dc.subjectParkinson's and Huntington's diseasesen_US
dc.subjectpolymorphsen_US
dc.subjectPrPSc aggregatesen_US
dc.subjectTrehalose'sen_US
dc.titleTrehalose and its Diverse Biological Potentialen_US
dc.title.journalCurrent Protein and Peptide Scienceen_US
dc.typeReviewen_US
dc.type.accesstypeClosed Accessen_US

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