Mechanisms of Anti-Tumor Activity of Withania somnifera (Ashwagandha)

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dc.contributor.authorMehta, V
dc.contributor.authorChander, H
dc.contributor.authorMunshi, A.
dc.date.accessioned2020-07-16T07:41:59Z
dc.date.accessioned2024-08-14T07:40:39Z
dc.date.available2020-07-16T07:41:59Z
dc.date.available2024-08-14T07:40:39Z
dc.date.issued2020
dc.description.abstractIncreasing herbal formulations have been used to treat several diseases including cancer. W. somnifera (Ashwagandha) is one such plant the extracts of which have been tested against a number of ailments including cancer, which remains as one of the most dreadful diseases on the globe. The ever-increasing number of cancer related mortality demands the development of novel chemopreventive agents with minimum side effects. Different compounds isolated from various parts of the plant like root, stem, and leaves have been reported to display significant anti-cancerous and immunomodulating properties and thus can be used alone or in combination with other chemotherapeutic drugs for cancer treatment. Through this review, we highlight the importance of W. somnifera in countering the potential oncogenic signaling mediators that are modulated by active constituents of W. somnifera in a variety of cancer types. Further, we hope that active constituents of W. somnifera will be tested in clinical trials so that they can be used as an important adjuvant in the near future for the effective treatment of cancer. � 2020, � 2020 Taylor & Francis Group, LLC.en_US
dc.identifier.doi10.1080/01635581.2020.1778746
dc.identifier.issn1635581
dc.identifier.urihttp://10.2.3.109/handle/32116/2690
dc.identifier.urlhttps://www.tandfonline.com/doi/full/10.1080/01635581.2020.1778746
dc.language.isoenen_US
dc.publisherRoutledgeen_US
dc.titleMechanisms of Anti-Tumor Activity of Withania somnifera (Ashwagandha)en_US
dc.title.journalNutrition and Canceren_US
dc.typeReviewen_US
dc.type.accesstypeClosed Accessen_US

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