Host-Guest Interaction of calix[4]arene derivatives with MetforminAC
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Date
2018
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Central University of Punjab
Abstract
Calix[4]arene was lower rim functionalized to furnish receptor 2-3 and 4-6, containing propyl and cyanomethoxy moieties, respectively. The receptors were characterized by FTIR, 1H and EI-MS. UV-visible studies were performed with receptor 2-6 cone (1'10-4M) upon addition of metformin (1'10-5 - 1'10-3M). Upon addition of metformin the UV-Visible absorption showed a hyperchromic shift.The 1:1 Host-Guest complexation studied by Benesi-Hildebrand equation showed a stability constant in the range 2'104 -10'104 M-1 .
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Keywords
Calix 4 arene, Host-guest complex, Metformin, Benesi-Hildebrand equation
Citation
Gupta, Harshita (2018) Host-Guest Interaction of calix[4]arene derivatives with MetforminAC