Overview of extraction of astaxanthin from Haematococcus pluvialis using CO2 supercritical fluid extraction technology vis-a-vis quality demands

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dc.contributor.authorSaini, Khem Chand
dc.contributor.authorYadav, Digvijay Singh
dc.contributor.authorMehariya, Sanjeet
dc.contributor.authorRathore, Parikshita
dc.contributor.authorKumar, Bikash
dc.contributor.authorMarino, Tiziana
dc.contributor.authorLeone, Gian Paolo
dc.contributor.authorVerma, Pradeep
dc.contributor.authorMusmarra, Dino
dc.contributor.authorMolino, Antonio
dc.date.accessioned2024-01-16T14:23:08Z
dc.date.accessioned2024-08-13T10:34:06Z
dc.date.available2024-01-16T14:23:08Z
dc.date.available2024-08-13T10:34:06Z
dc.date.issued2021-04-19T00:00:00
dc.description.abstractMicroalgae biomass have been used as a source of nutrient-rich food, feed, and health-promoting compounds. Among the several commercially available microalgae, Haematococcus pluvialis is the most abundant source of natural astaxanthin (3, 3'-dihydroxy-?, ?-carotene-4, 4'-dione), which is considered as �super antioxidant.� Therefore natural astaxanthin produced by H. pluvialis has a higher antioxidant capacity than the synthetic sources, which reduces oxidative stress and free radicals and helps the human body to maintain a healthy state. However, H. pluvialis contains astaxanthin inside the cells, which need to be extracted using nontoxic extraction technologies for different application. Among the different available extraction technologies, supercritical fluid extraction (SFE) is a modern technology with increasing applications in pharmaceutical and nutraceutical sector. The most frequently employed supercritical solvent in food and natural product processing is carbon dioxide (CO2) due to its low critical temperature and pressure while considered as nontoxic extraction solvent. Therefore, nowadays, supercritical carbon dioxide (SC-CO2) is considered as a new substitute for complete extraction of natural compounds from different matrices. However, the extraction efficiency and purity of astaxanthin in the extract are influenced by different operative conditions such as the extraction pressure, temperature, time, and use of cosolvent. Hence the optimum operative condition of SC-CO2 extraction could enhance the extraction yields of astaxanthin and of its purity the extract. Therefore present chapter summarizes the effects of several extraction parameters on SC-CO2 extraction of astaxanthin from H. pluvialis, which could serve as benchmark for future development of SC-CO2 extraction technology and its commercial implementation in pharmaceutical and nutraceutical sector. � 2021 Elsevier Inc.en_US
dc.identifier.doi10.1016/B978-0-12-823304-7.00032-5
dc.identifier.isbn9.78013E+12
dc.identifier.urihttps://doi.org/10.1016/B978-0-12-823304-7.00032-5
dc.identifier.urihttp://10.2.3.109/handle/32116/2848
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.subjectAstaxanthinen_US
dc.subjectCosolventen_US
dc.subjectHaematococcus pluvialisen_US
dc.subjectNatural antioxidanten_US
dc.subjectPharmaceuticalen_US
dc.subjectSupercritical carbon dioxide extractionen_US
dc.titleOverview of extraction of astaxanthin from Haematococcus pluvialis using CO2 supercritical fluid extraction technology vis-a-vis quality demandsen_US
dc.title.journalGlobal Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applicationsen_US
dc.typeBook chapteren_US
dc.type.accesstypeClosed Accessen_US

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