An Overview on Biological Evaluation of Tetrazole Derivatives

dc.contributor.authorKabi, Arup K.
dc.contributor.authorSravani, Sattu
dc.contributor.authorGujjarappa, Raghuram
dc.contributor.authorGarg, Aakriti
dc.contributor.authorVodnala, Nagaraju
dc.contributor.authorTyagi, Ujjawal
dc.contributor.authorKaldhi, Dhananjaya
dc.contributor.authorVelayutham, Ravichandiran
dc.contributor.authorSingh, Virender
dc.contributor.authorGupta, Sreya
dc.contributor.authorMalakar, Chandi C.
dc.date.accessioned2024-01-21T10:33:00Z
dc.date.accessioned2024-08-13T11:16:43Z
dc.date.available2024-01-21T10:33:00Z
dc.date.available2024-08-13T11:16:43Z
dc.date.issued2022-03-07T00:00:00
dc.description.abstractTetrazoles are distinguished by a five-membered, doubly unsaturated ring which consists of four nitrogen and one carbon atom with a molecular formula CN4H2, which have a wide range of medicinal activity and potential role in biosciences. Interest in tetrazole chemistry in recent decades has been increasing rapidly because of diverse biological and pharmaceutical applications, mostly due to the diversity of this N-heterocyclic moiety in medicinal chemistry. This moiety offers a more appreciative pharmacokinetic profile and plays the role of metabolically stable substitute for carboxylic acid functional group as well as exhibits a broad range of biological effects such as analgesic, antibacterial, anticancer, anti-inflammatory, antidiabetic, antifungal, antitubercular and antihyperlipidemic activities. This chapter highlights the unique features of the potential possible role of tetrazole derivatives and summarizes biological and pharmacological activities. � 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.en_US
dc.identifier.doi10.1007/978-981-16-8399-2_8
dc.identifier.issn25245384
dc.identifier.urihttp://10.2.3.109/handle/32116/3236
dc.identifier.urlhttps://link.springer.com/10.1007/978-981-16-8399-2_8
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.subjectAngiotensinogenen_US
dc.subjectDrug discoveryen_US
dc.subjectN-heterocyclesen_US
dc.subjectPharmacophoreen_US
dc.subjectTetrazolesen_US
dc.titleAn Overview on Biological Evaluation of Tetrazole Derivativesen_US
dc.title.journalMaterials Horizons: From Nature to Nanomaterialsen_US
dc.typeBook chapteren_US
dc.type.accesstypeClosed Accessen_US

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