Role of nanoparticles in the treatment of human disease: a comprehensive review
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Date
2022-12-09T00:00:00
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Publisher
Elsevier
Abstract
Nanoparticles (NPs) are nanosize particles which can be employed to treat human diseases and enhance the potential of existing drugs. The NPs can overcome biological barriers and enhance the drug delivery to the target site and thus increase efficiency of the drug. NPs are classified into various types, including polymeric, inorganic, and lipid-based NPs. In addition different types of NPs are used in medical fields, such as chitosan, alginate, cellulose, and liposome-based. The NPs have offered many advantages in disease diagnostic and therapeutic with the safe delivery of the various drugs into the tissue. In the past few years, the usage of nanotechnology in medicine has led to the improvement of vaccine efficiency, immunity strategies, and targeted delivery to attain a positive immune response at the cellular level and to advance vaccine efficiency. The NP carriers should defend the antigens from premature proteolytic degradation, ease antigen uptake and processing by antigen-presenting cells, control release, and be harmless for human consumption. This review chapter presents a summary of the current research and future trends in the use of NPs in the treatment of diseases with an emphasis on drug delivery. � 2023 Elsevier Inc. All rights reserved.
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Keywords
nanocrystal, nanodevices, nanomaterials, Nanoparticles, nanotechnology, polymeric micelles