Identification of novel translocation between short arm of chromosome 4 and long arm of chromosome 6 in an infertile man using Interphase Chromosome Profiling (ICP)
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Blackwell Publishing Ltd
Abstract
Conventional cytogenetics has always been a favourite to detect chromosomal aberrations. Carriers of chromosomal translocation are often phenotypically normal but are infertile. Couples are often advised to go for karyotyping, but culture failure or improper metaphase spread with poor banding often makes the analysis difficult. We report here a novel translocation between short arm of chromosome 4 and long arm of chromosome 6 in an infertile man using an advanced molecular cytogenetic technique of Interphase Chromosome Profiling (ICP). ? 2018 Blackwell Verlag GmbH
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Keywords
Article, Case Report, Chromosome 4, Chromosome 6, Chromosome Analysis, Chromosome Translocation, Clinical Article, Cytogenetics, Human, Hybridization, Interphase Chromosome Profiling, Lymphocyte Culture, Male, Male Infertility, Molecular Genetics, Spontaneous Abortion
Citation
Kaul, S., Kaur, H., Vats, S. K. S., Chawla, J., Jindal, R., & Khetarpal, P. (2018). Identification of novel translocation between short arm of chromosome 4 and long arm of chromosome 6 in an infertile man using Interphase Chromosome Profiling (ICP). Andrologia, 50(4). doi: 10.1111/and.12954