Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents

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dc.contributor.authorSingh, Harshwardhan
dc.contributor.authorAnila, Kumari V. S.
dc.contributor.authorSingh, Ankit Kumar
dc.contributor.authorKumar, Adarsh
dc.contributor.authorKumar, Pradeep
dc.date.accessioned2024-01-21T10:38:38Z
dc.date.accessioned2024-08-13T12:05:34Z
dc.date.available2024-01-21T10:38:38Z
dc.date.available2024-08-13T12:05:34Z
dc.date.issued2023-10-11T00:00:00
dc.description.abstractTuberculosis (TB) is the major cause of mortality around the world and one of the most common diseases linked to AIDS. Due to the emergence of multi-drug resistance, extensive drug resistance, and total drug resistance strains, TB has become a difficult disease to treat. Isoxazole scaffold shows a wide range of biological activities, including anticancer, antibacterial, anti-tubercular, antiviral, and anti-inflammatory activities etc. Several isoxazole derivatives have been produced and few of them have shown comparable anti-tubercular activity with standard drugs. In this review, we have focused on reported isoxazole derivatives having anti-tubercular activity and summarized their structure-activity relationship. � 2023 Bentham Science Publishers.en_US
dc.identifier.doi10.2174/0113852728264519231006055100
dc.identifier.issn13852728
dc.identifier.urihttp://10.2.3.109/handle/32116/3621
dc.identifier.urlhttps://www.eurekaselect.com/221932/article
dc.language.isoen_USen_US
dc.publisherBentham Science Publishersen_US
dc.subjectanti-tubercular agentsen_US
dc.subjectinflammatoryen_US
dc.subjectIsoxazoleen_US
dc.subjectmedicinal chemistryen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjecttuberculosisen_US
dc.titleMedicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agentsen_US
dc.title.journalCurrent Organic Chemistryen_US
dc.typeShort surveyen_US
dc.type.accesstypeClosed Accessen_US

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