Nanosilica: Recent Progress in Synthesis, Functionalization, Biocompatibility, and Biomedical Applications

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dc.contributor.authorSingh P.
dc.contributor.authorSrivastava S.
dc.contributor.authorSingh S.K.
dc.date.accessioned2020-01-31T11:33:54Z
dc.date.accessioned2024-08-13T13:22:14Z
dc.date.available2020-01-31T11:33:54Z
dc.date.available2024-08-13T13:22:14Z
dc.date.issued2019
dc.description.abstractSilica nanoparticles (Si-NPs) are widely explored in biomedical applications due to their high surface area, excellent biocompatibility, and tunable pore size. The silica surface can be readily functionalized for wide range of applications such as cellular imaging, biosensing, and targeted drug delivery. This comprehensive review discusses different synthesis methodologies of Si-NPs and their surface functionalization with various functional groups. Nanosilica functionalization methods are discussed in detail, emphasizing their suitability for targeted drug delivery, cancer therapy, bioimaging, and biosensing. The toxicity assessment of nanosilica is also critically reviewed to get a clear focus before employing them for nanomedicine.en_US
dc.identifier.doi10.1021/acsbiomaterials.9b00464
dc.identifier.issn23739878
dc.identifier.urihttp://10.2.3.109/handle/32116/2505
dc.identifier.urlhttps://pubs.acs.org/doi/10.1021/acsbiomaterials.9b00464
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.subjectbiosensingen_US
dc.subjectdrug deliveryen_US
dc.subjectfunctionalizationen_US
dc.subjectmesoporousen_US
dc.subjectsilica nanoparticlesen_US
dc.titleNanosilica: Recent Progress in Synthesis, Functionalization, Biocompatibility, and Biomedical Applicationsen_US
dc.title.journalACS Biomaterials Science and Engineeringen_US
dc.typeArticleen_US
dc.type.accesstypeClosed Accessen_US

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