Natural Compounds as Potential Anti-COVID Agents

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dc.contributor.authorRani, Nidhi
dc.contributor.authorSingh, Randhir
dc.contributor.authorKumar, Praveen
dc.contributor.authorSharma, Prerna
dc.contributor.authorSharma, Vikas
dc.date.accessioned2024-01-21T10:55:02Z
dc.date.accessioned2024-08-14T07:44:19Z
dc.date.available2024-01-21T10:55:02Z
dc.date.available2024-08-14T07:44:19Z
dc.date.issued2022-04-05T00:00:00
dc.description.abstractBackground: Since December 2019, COVID-19 has become a new health crisis in the world and has been declared a public health emergency of international concern by WHO. In search of anti-COVID treatment regimen, we applied molecular docking approach in order to identify the natural compounds that may have potential for anti-COVID treatment with specific target and selective inhibitory mechanism. Our goal is to identify the potential anti-COVID compounds based on virtual screening of the protein of spike glycoprotein as virtual inhibition target. Methods: Molecular docking was carried out by using Molergo Virtual Docker. 35 compounds from different plant sources were selected and docked in the enzyme pocket. Results: The docking result revealed that some of the compounds exhibited good potency against the virus and can be used further for developing new drug regimen. Conclusion: The compounds of natural origin could be a good target and can be used as lead compounds for the treatment of this dreadful disease. � 2023 Bentham Science Publishers.en_US
dc.identifier.doi10.2174/2211352520666220404093338
dc.identifier.issn22113525
dc.identifier.urihttp://10.2.3.109/handle/32116/4315
dc.identifier.urlhttps://www.eurekaselect.com/203043/article
dc.language.isoen_USen_US
dc.publisherBentham Science Publishersen_US
dc.subjectCoronavirusen_US
dc.subjectCOVID19en_US
dc.subjectMERSen_US
dc.subjectnatural plantsen_US
dc.subjectspike glycoproteinen_US
dc.subjectWHOen_US
dc.titleNatural Compounds as Potential Anti-COVID Agentsen_US
dc.title.journalAnti-Infective Agentsen_US
dc.typeArticleen_US
dc.type.accesstypeClosed Accessen_US

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