Naturally occurring fused pyrimidine derivatives and their medicinal attributes

Abstract

A wide variety of fused pyrimidine derivatives, mainly occurring as alkaloids, are obtained from different natural sources worldwide. These have been documented to exert some important biological activities including anticancer, antimicrobial, anti-inflammatory, etc. Based on the natural source, these fused pyrimidine derivatives are categorized and discussed further in the subsequent sections highlighting their medicinal attributes. � 2023 Elsevier Ltd. All rights reserved.