Naturally available nitrogen-containing fused heterocyclics as prospective lead molecules in medicinal chemistry

Abstract

Heterocyclic compounds constitute one of the largest and most versatile families of organic compounds. There are many heterocyclic compounds that are being isolated from natural sources and day by day the number is increasing rapidly due to their enormous utili-ty. Nitrogen containing heterocyclic compounds have a prominent role in medicinal chemis-try, biochemistry and other streams of science. In this review, we have covered most of the biologically active nitrogen containing heterocyclic compounds obtained from the natural sources including indole, carbazole, quinoline, isoquinoline and benzothiazole ring system. These isolated nitrogen containing heterocyclic compounds render wide spectrum of biological activities including antifungal, anti-inflammatory, antibacterial, antioxidants, anticonvul-sant, anti-allergic, herbicidal and anticancer activities. � 2021 Bentham Science Publishers.