Traditional Drugs Originating from Selected Medicinal Plants: An Intervention for Anaemia

dc.contributor.authorChalotra, Rishabh
dc.contributor.authorDhanawat, Meenakshi
dc.contributor.authorMaivagna, Chamasse Homary
dc.contributor.authorGupta, Sumeet
dc.date.accessioned2024-01-21T10:55:09Z
dc.date.accessioned2024-08-14T07:44:23Z
dc.date.available2024-01-21T10:55:09Z
dc.date.available2024-08-14T07:44:23Z
dc.date.issued2023-01-06T00:00:00
dc.description.abstractBackground: Anaemia is the most common disease that affects mostly females and children and is most prevalent in developing countries. Among various causes sickle cell anaemia is one of them, which is a cause of concern. Sickle Cell Disease (SCD) causes problems like blockage of blood flow, causing pain, and fatigue and also leads to death. Objective: With the advancement in science, diseases that were once considered unable to cure can be stopped or prevented and, in some cases, also be cured. As current therapies for the treatment of sickle cell anaemia are limited, like blood transfusions, bone marrow transfusions, etc., a non-surgical method where plant extracts or compounds were found effective in stopping, preventing, and in some cases rever-sal of SCD. In this review, we tried to gather information about those plants and compounds. Methods: Numerous surveys in the literature were performed to determine the plants which have shown their potential against SCD. Relevant peer-reviewed publications were searched through various databases such as ScienceDirect, PubMed, Google Scholar, Research Gate, etc. Results: A total of more than 50 medicinal plants such as Acacia catechu, Alchornea cordifolia, Anchomanes difformis, Khayase negalensis, Terminalia catappa, etc., have been identified based on their potential against SCD, and 15 compounds such as Butylurea, Glyceraldehyde, Potassium cya-nate, urea, etc., have also been identified which could work against SCD. These plants acting on sickle cell anemia on various pathways are also discussed. Conclusion: In this review, an approach was made to study those plants which have an effect against SCD, with proper mechanisms and compounds that show potency against this disease. So that better treatment options could be available for future generations. � 2023 Bentham Science Publishers.en_US
dc.identifier.doi10.2174/2215083809666230105161143
dc.identifier.issn22150838
dc.identifier.urihttps://kr.cup.edu.in/handle/32116/4354
dc.identifier.urlhttps://www.eurekaselect.com/212400/article
dc.language.isoen_USen_US
dc.publisherBentham Science Publishersen_US
dc.subjectanaemiaen_US
dc.subjectanti-sicklingen_US
dc.subjectherbal medicinesen_US
dc.subjectSickle cellen_US
dc.subjectsickle cell diseaseen_US
dc.subjectVOCsen_US
dc.titleTraditional Drugs Originating from Selected Medicinal Plants: An Intervention for Anaemiaen_US
dc.title.journalCurrent Traditional Medicineen_US
dc.typeShort surveyen_US
dc.type.accesstypeClosed Accessen_US

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