Cytotoxic activity of saragassum wightii on pc-3 cancer cell-line

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dc.contributor.authorJahid, Mohd.
dc.contributor.supervisorBast, Felix
dc.date.accessioned2018-08-30T05:10:36Z
dc.date.accessioned2018-08-30T06:09:22Z
dc.date.accessioned2024-08-13T10:50:41Z
dc.date.available2018-08-30T05:10:36Z
dc.date.available2018-08-30T06:09:22Z
dc.date.available2024-08-13T10:50:41Z
dc.date.issued2012
dc.description.abstractFinding novel antitumor compounds with low side effects could be an interesting proposal. Antioxidant and anticancer potentials of seaweed extracts can possibly be explored for developing the new anticancer drugs. Polyphenols are extensively distributed in seaweeds and these are reported to be free radical scavengers. This study was designed to check the cytotoxic potential of the methanolic and hydromethanolic extracts from the brown algae S. wightii. The total phenolic content in the hydromethanolic extract and the methanolic extract of S. wightii was determined by the Folin-Ciocalteu method. The total phenolic content in methanolic extract was found to be greater than hydromethanolic extract. The percentage inhibition or scavenging activity of both the extracts was calculated by using the DPPH assay and was more for the methanolic extract. PC-3 cancer cell-line was used as an experimental model. The methanolic crude extract is significantly cytotoxic against the PC-3 cancer cells. On the other hand the hydromethanolic crude extract was not found to be the significantly cytotoxic against the PC-3 cancer cells.en_US
dc.identifier.accessionnoT00013
dc.identifier.citationJahid, Mohd (2012) Cytotoxic activity of saragassum wightii on pc-3 cancer cell-line.en_US
dc.identifier.urihttp://10.2.3.109/handle/32116/1727
dc.language.isoen_USen_US
dc.publisherCentral University of Punjaben_US
dc.subjectSargassum wightiien_US
dc.subjectMethanolic extracten_US
dc.subjectHydromethanolic extracten_US
dc.subjectCytotoxicityen_US
dc.subjectPC-3 cell-lineen_US
dc.titleCytotoxic activity of saragassum wightii on pc-3 cancer cell-lineen_US
dc.typeMphil Dissertationen_US

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