Synthesis and characterization of 2-aminothiophene derivatives by Gewald reaction

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dc.contributor.authorPratibha, Agarwala
dc.contributor.supervisorVenkata Rao, Kaki
dc.date.accessioned2018-08-31T04:13:48Z
dc.date.accessioned2024-08-13T11:24:39Z
dc.date.available2018-08-31T04:13:48Z
dc.date.available2024-08-13T11:24:39Z
dc.date.issued2018
dc.description.abstractSubstituted thiophene derivatives are very important heterocycles found in many biologically active and natural compounds. The Gewald multicomponent reaction was a remarkable discovery for the synthesis of wide variety of thiophene derivatives. Also the synthesis of the thieno pyrimidine derivatives as potential surrogates for this quinazoline core structure has, therefore, became a routine strategy in modern drug design and development. So we want do some multistep reaction to prepare thienopyrimidine derivative from thiophene which are very important core intermediates with various biological applications like anti-tumor, anti-bacterial, anti-microbial, anti-cancer agents.en_US
dc.identifier.accessionnoT00632
dc.identifier.citationPratibha, Agarwala (2018) Synthesis and characterization of 2-aminothiophene derivatives by Gewald reaction.en_US
dc.identifier.urihttp://10.2.3.109/handle/32116/1933
dc.language.isoen_USen_US
dc.publisherCentral University of Punjaben_US
dc.subjectMulticomponent Reactionsen_US
dc.subject2-minothiophenesen_US
dc.subjectthieno[2en_US
dc.subject3-d]pyrimidinesen_US
dc.subjectGewald Reactionen_US
dc.titleSynthesis and characterization of 2-aminothiophene derivatives by Gewald reactionen_US
dc.typeMaster Dissertationen_US

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