Invitro anti-mutagenic potential of potentilla fulgens: A western himalayan plant
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Date
2014
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Publisher
Informatics Publishing Limited
Abstract
Invitro anti-mutagenic potential of different extracts/fractions of Potentilla fulgens has been made by an Ames histidine reversion assay using TA98 and TA100 tester strains of Salmonella typhimurium against the direct-acting mutagens, 4-Nitro-O-phenylenediamine (NPD) and Sodium azide. P. fulgens has been used in traditional system of medicine as anti-hyperglycemic, hypoglycemic, anti-hyperlipidemic, anti-oxidant, anti-inflammatory and anti-ulcerogenic agent. Results indicated that n-butanol and water fractions showed strong inhibition activity against the mutagens (NPD, Sodium azide) in both co-incubation as well as pre-incubation treatments in TA98 and TA100 tester strains. ? 2017, Informatics Publishing Limited. All rights reserved.
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Keywords
Antimutagenic agent, Butanol, Phenylenediamine derivative, Plant extract, Sodium azide, Water controlled study, Drug activity, In vitro study, Inhibitory dose, Mutagenicity, Non human, Potentilla, Potentilla fulgens, Revertant, Salmonella enterica serovar Typhimurium
Citation
Monga, P., Kaur, R., & Jaitak, V. (2014). Invitro anti-mutagenic potential of potentilla fulgens: A western himalayan plant. Journal of Natural Remedies, 14(2), 144-152. doi: 10.18311/jnr/2014/76