Kishore, Pendyala SatyaGujjarappa, RaghuramPutta, V. P. Rama KishorePolina, SaibabuSingh, VirenderMalakar, Chandi C.Pujar, Prasad Pralhad2024-01-212024-08-132024-01-212024-08-132022-12-082365654910.1002/slct.202204238https://kr.cup.edu.in/handle/32116/3261KOtBu mediates the reaction between 2-amino arylcarbaldehydes and benzyl/alkyl cyanides toward the expeditious formation of 2-aminoquinolines under transition-metal-free conditions. The described transformation proceeds through in-situ generated enimine intermediate from benzyl/alkyl cyanides under KOtBu-mediated reaction conditions. The substituted 2-aminoquinolines were realized in excellent yields at room temperature and shorter reaction time. The designed process exhibits operational simplicity and broad functional group tolerance in delivering the products of high significance. � 2022 Wiley-VCH GmbH.en-US2-Amino arylcarbaldehydes2-AminoquinolinesAlkyl cyanidesKO^tBuTransition-metal-freeArticlehttps://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202204238