Saini, Geetika2018-08-312024-08-132018-08-312024-08-132018Saini, Geetika (2018) Synthesis, Characterization and Biological Evaluation of 5-(2- Nitrophenyl)-1H-Pyrazole Derivatives as Putative Antiproliferative Agentshttp://10.2.3.109/handle/32116/1931Pyrazoles are known to exhibit various biological activities like antibacterial, antiprotozoal, anticonvulsant, analgesic, anti-inflammatory, antiviral and antiproliferative. An attempt has been made to synthesize substituted pyrazoles. Their antiproliferative activity was determined by performing MTT assay on MDA-MB 231 cell line (breast cancer). The compounds were further docked into topoisomerase 1 and 2en-USCancerTopoisomerasePyrazoleAntiproliferativeSynthesisMaster DissertationT00630