AnjuKumar, AmitYadav, PoonamNavik, UmashankerJaitak, Vikas2024-01-212024-08-142024-01-212024-08-142022-08-081478641910.1080/14786419.2022.2107642http://10.2.3.109/handle/32116/4331Chemical composition of the essential oil (EO) of Eucalyptus tereticornis leaves was studied by gas chromatography�mass spectrometry. Forty-five constituents were identified in the oil hydrodistilled from the sample collected from Ghudda Village, Bathinda (Pb), India of which eucalyptol (34.39%) and ledol (9.92%) were the major constituents. In vitro antioxidant and anticancer potential of EO was analysed by DPPH 2,2-diphenylpicrylhydrazyl (DPPH) and MTT assay. The percentage free radical scavenging activity was found to be 63.77%. The antiproliferative activity was analysed using MTT assay in adenocarcinomic human alveolar basal epithelial A549 cancer cell line and showed IC50 value of 47.14 �g/ml. In silico study of EO, constituents were performed using Maestro 12.9 against EGFR (PDB ID-2RGP). Five constituents from EO showed high dockscore as compared to standard Mobicertinib which indicated the effectiveness of oil constituents against lung cancer. � 2022 Informa UK Limited, trading as Taylor & Francis Group.en-USantioxidantantiproliferationessential oilEucalyptus tereticornisGC�MSin silicolung cancerArticlehttps://www.tandfonline.com/doi/full/10.1080/14786419.2022.2107642